Polyphenols are plant food microconstituents that are widely distributed in the human diet, with fruits and fruit-derived products as one of the main dietary sources. Epidemiological studies have shown an inverse relationship between the intake of different classes of polyphenols and the risk of myocardial infarction or cardiovascular disease (CVD) mortality. These compounds have been associated with the promotion of cardiovascular health as evidenced by clinical studies reporting beneficial effects of polyphenol-rich fruit consumption on intermediate markers of cardiovascular diseases. Additionally, animal and in vitro studies have indicated positive roles of polyphenols in preventing dysfunctions associated with the development of cardiovascular diseases. However, the mechanisms of action underlying their beneficial effects appear complex and are not fully understood. This review aims to provide an update on the nutrigenomic effects of different groups of polyphenols from fruits and ...especially focuses on their cardiovascular protective effects in cell and animal studies.
Source:
Food & Function, 2016, 7, 9, 3656-3676
Publisher:
Royal Soc Chemistry, Cambridge
Funding / projects:
COST action [FA1403—POSITIVe], Interindividual variation in response to consumption of plant food bioactives and determinants involved
TY - JOUR
AU - Krga, Irena
AU - Milenković, Dragan
AU - Morand, Christine
AU - Monfoulet, Laurent-Emanuel
PY - 2016
UR - http://rimi.imi.bg.ac.rs/handle/123456789/702
AB - Polyphenols are plant food microconstituents that are widely distributed in the human diet, with fruits and fruit-derived products as one of the main dietary sources. Epidemiological studies have shown an inverse relationship between the intake of different classes of polyphenols and the risk of myocardial infarction or cardiovascular disease (CVD) mortality. These compounds have been associated with the promotion of cardiovascular health as evidenced by clinical studies reporting beneficial effects of polyphenol-rich fruit consumption on intermediate markers of cardiovascular diseases. Additionally, animal and in vitro studies have indicated positive roles of polyphenols in preventing dysfunctions associated with the development of cardiovascular diseases. However, the mechanisms of action underlying their beneficial effects appear complex and are not fully understood. This review aims to provide an update on the nutrigenomic effects of different groups of polyphenols from fruits and especially focuses on their cardiovascular protective effects in cell and animal studies.
PB - Royal Soc Chemistry, Cambridge
T2 - Food & Function
T1 - An update on the role of nutrigenomic modulations in mediating the cardiovascular protective effect of fruit polyphenols
EP - 3676
IS - 9
SP - 3656
VL - 7
DO - 10.1039/c6fo00596a
UR - conv_3851
ER -
@article{
author = "Krga, Irena and Milenković, Dragan and Morand, Christine and Monfoulet, Laurent-Emanuel",
year = "2016",
abstract = "Polyphenols are plant food microconstituents that are widely distributed in the human diet, with fruits and fruit-derived products as one of the main dietary sources. Epidemiological studies have shown an inverse relationship between the intake of different classes of polyphenols and the risk of myocardial infarction or cardiovascular disease (CVD) mortality. These compounds have been associated with the promotion of cardiovascular health as evidenced by clinical studies reporting beneficial effects of polyphenol-rich fruit consumption on intermediate markers of cardiovascular diseases. Additionally, animal and in vitro studies have indicated positive roles of polyphenols in preventing dysfunctions associated with the development of cardiovascular diseases. However, the mechanisms of action underlying their beneficial effects appear complex and are not fully understood. This review aims to provide an update on the nutrigenomic effects of different groups of polyphenols from fruits and especially focuses on their cardiovascular protective effects in cell and animal studies.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Food & Function",
title = "An update on the role of nutrigenomic modulations in mediating the cardiovascular protective effect of fruit polyphenols",
pages = "3676-3656",
number = "9",
volume = "7",
doi = "10.1039/c6fo00596a",
url = "conv_3851"
}
Krga, I., Milenković, D., Morand, C.,& Monfoulet, L.. (2016). An update on the role of nutrigenomic modulations in mediating the cardiovascular protective effect of fruit polyphenols. in Food & Function
Royal Soc Chemistry, Cambridge., 7(9), 3656-3676.
https://doi.org/10.1039/c6fo00596a
conv_3851
Krga I, Milenković D, Morand C, Monfoulet L. An update on the role of nutrigenomic modulations in mediating the cardiovascular protective effect of fruit polyphenols. in Food & Function. 2016;7(9):3656-3676.
doi:10.1039/c6fo00596a
conv_3851 .
Krga, Irena, Milenković, Dragan, Morand, Christine, Monfoulet, Laurent-Emanuel, "An update on the role of nutrigenomic modulations in mediating the cardiovascular protective effect of fruit polyphenols" in Food & Function, 7, no. 9 (2016):3656-3676,
https://doi.org/10.1039/c6fo00596a .,
conv_3851 .
