Quantification of biofilm formation on silicone intranasal splints: an in vitro study

2016
Authors
Pavlović, BojanBožić, Dragana D.

Milovanović, Jovica
Jotić, Ana

Đukić, Vojko
Đukić, Slobodanka
Konstantinović, Neda M.

Ćirković, Ivana

Article (Published version)

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Objectives: Biofilms are associated with persistent infections and resistant to conventional therapeutic strategies. The aim of this study was to investigate the quantity of biofilm produced on silicone intranasal splints. Methods: Quantity of biofilm formation on silicone splints (SS) was tested on 15 strains of Staphylococcus aureus and Moraxella catarrhalis, respectively. Antimicrobial susceptibility testing was performed in accordance with European Committee on Antimicrobial Susceptibility Testing recommendations. Results: All tested strains formed different amounts of biofilm on SS: 66.7% S. aureus and 93.3% M. catarrhalis were weak biofilm producers and 33.3% S. aureus and 6.7% M. catarrhalis were moderate biofilm producers. S. aureus formed significantly higher quantity of biofilm compared with M. catarrhalis (p lt 0.05). Multidrug resistant S. aureus produced significantly higher amount of biofilm compared with non-multidrug resistant strains (p lt 0.05). Conclusion: Quanti...ty of biofilm on SS is highly dependent on bacterial species and their resistance patterns. Future studies are needed to ascertain another therapeutic option for prophylaxis prior to SS placement.
Keywords:
silicone intranasal splints / biofilm formation / quantification / Staphylococcus aureus / Moraxella catarrhalisSource:
Acta Microbiologica et Immunologica Hungarica, 2016, 63, 3, 301-311Publisher:
- Akademiai Kiado Rt, Budapest
DOI: 10.1556/030.63.2016.006
ISSN: 1217-8950
PubMed: 27682847
WoS: 000384749200004
Scopus: 2-s2.0-84990181877
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Institut za medicinska istraživanjaTY - JOUR AU - Pavlović, Bojan AU - Božić, Dragana D. AU - Milovanović, Jovica AU - Jotić, Ana AU - Đukić, Vojko AU - Đukić, Slobodanka AU - Konstantinović, Neda M. AU - Ćirković, Ivana PY - 2016 UR - http://rimi.imi.bg.ac.rs/handle/123456789/695 AB - Objectives: Biofilms are associated with persistent infections and resistant to conventional therapeutic strategies. The aim of this study was to investigate the quantity of biofilm produced on silicone intranasal splints. Methods: Quantity of biofilm formation on silicone splints (SS) was tested on 15 strains of Staphylococcus aureus and Moraxella catarrhalis, respectively. Antimicrobial susceptibility testing was performed in accordance with European Committee on Antimicrobial Susceptibility Testing recommendations. Results: All tested strains formed different amounts of biofilm on SS: 66.7% S. aureus and 93.3% M. catarrhalis were weak biofilm producers and 33.3% S. aureus and 6.7% M. catarrhalis were moderate biofilm producers. S. aureus formed significantly higher quantity of biofilm compared with M. catarrhalis (p lt 0.05). Multidrug resistant S. aureus produced significantly higher amount of biofilm compared with non-multidrug resistant strains (p lt 0.05). Conclusion: Quantity of biofilm on SS is highly dependent on bacterial species and their resistance patterns. Future studies are needed to ascertain another therapeutic option for prophylaxis prior to SS placement. PB - Akademiai Kiado Rt, Budapest T2 - Acta Microbiologica et Immunologica Hungarica T1 - Quantification of biofilm formation on silicone intranasal splints: an in vitro study EP - 311 IS - 3 SP - 301 VL - 63 DO - 10.1556/030.63.2016.006 UR - conv_3857 ER -
@article{ author = "Pavlović, Bojan and Božić, Dragana D. and Milovanović, Jovica and Jotić, Ana and Đukić, Vojko and Đukić, Slobodanka and Konstantinović, Neda M. and Ćirković, Ivana", year = "2016", abstract = "Objectives: Biofilms are associated with persistent infections and resistant to conventional therapeutic strategies. The aim of this study was to investigate the quantity of biofilm produced on silicone intranasal splints. Methods: Quantity of biofilm formation on silicone splints (SS) was tested on 15 strains of Staphylococcus aureus and Moraxella catarrhalis, respectively. Antimicrobial susceptibility testing was performed in accordance with European Committee on Antimicrobial Susceptibility Testing recommendations. Results: All tested strains formed different amounts of biofilm on SS: 66.7% S. aureus and 93.3% M. catarrhalis were weak biofilm producers and 33.3% S. aureus and 6.7% M. catarrhalis were moderate biofilm producers. S. aureus formed significantly higher quantity of biofilm compared with M. catarrhalis (p lt 0.05). Multidrug resistant S. aureus produced significantly higher amount of biofilm compared with non-multidrug resistant strains (p lt 0.05). Conclusion: Quantity of biofilm on SS is highly dependent on bacterial species and their resistance patterns. Future studies are needed to ascertain another therapeutic option for prophylaxis prior to SS placement.", publisher = "Akademiai Kiado Rt, Budapest", journal = "Acta Microbiologica et Immunologica Hungarica", title = "Quantification of biofilm formation on silicone intranasal splints: an in vitro study", pages = "311-301", number = "3", volume = "63", doi = "10.1556/030.63.2016.006", url = "conv_3857" }
Pavlović, B., Božić, D. D., Milovanović, J., Jotić, A., Đukić, V., Đukić, S., Konstantinović, N. M.,& Ćirković, I.. (2016). Quantification of biofilm formation on silicone intranasal splints: an in vitro study. in Acta Microbiologica et Immunologica Hungarica Akademiai Kiado Rt, Budapest., 63(3), 301-311. https://doi.org/10.1556/030.63.2016.006 conv_3857
Pavlović B, Božić DD, Milovanović J, Jotić A, Đukić V, Đukić S, Konstantinović NM, Ćirković I. Quantification of biofilm formation on silicone intranasal splints: an in vitro study. in Acta Microbiologica et Immunologica Hungarica. 2016;63(3):301-311. doi:10.1556/030.63.2016.006 conv_3857 .
Pavlović, Bojan, Božić, Dragana D., Milovanović, Jovica, Jotić, Ana, Đukić, Vojko, Đukić, Slobodanka, Konstantinović, Neda M., Ćirković, Ivana, "Quantification of biofilm formation on silicone intranasal splints: an in vitro study" in Acta Microbiologica et Immunologica Hungarica, 63, no. 3 (2016):301-311, https://doi.org/10.1556/030.63.2016.006 ., conv_3857 .