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Utilization of ultrasound as a diagnostic tool in the preoperative assessment of patients with adnexal masses

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Authors
Terzić, Milan
Dotlić, Jelena
Bila, Jovan
Pilić, Igor
Nikolić, Branka
Kocijancić, Dušica
Likić, Ivana
Arsenović, Nebojša
Mihailović, Tihomir
Bugarski, Diana
Article (Published version)
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Abstract
Purpose: To evaluate the reliability of ultrasound scan (US) findings in the preoperative assessment of the nature of adnexal masses in females. Methods: After detailed history, a preoperative US examination was performed in all women. Tumor diameter, localization, the presence of solid, cystic and multilocular components, excrescences, metastasis and free fluid were assessed. Doppler scan was done and pulsatility (PI) and resistance indices (RI) were determined. These data were compared with postoperatively obtained histo pathological findings and statistically analyzed. Results: The study included 609 women out of which 20.7% had malignant, 73.7% benign, and 5.6% borderline tumors. Patients with malignant tumors were oldest (p lt 0.001). There were significantly more positive US parameters in malignant than in benign tumors (p lt 0.001). Also, there were significant differences (p lt 0.001) between malignant, benign and borderline tumors regarding all examined US and Doppler paramet...ers except tumor multilocularity. RI had sensitivity 75%, specificity 61.2%, positive predictive value (PPV) 42.70% and negative predictive value (NPV) 96.16%. PI had sensitivity 50%, specificity 35.3%, PPV 8.37% and NPV 25.93%. Sensitivity of US characteristics was 94.34%, specificity 30.62%. PPV 22.27% and NPV 96.25%. Conclusions: US pattern characteristics and Doppler parameters were found to be moderately reliable in discriminating malignant, benign and borderline adnexal tumors. Tumor of solid or mixed consistency, presence of ascites and excrescences were the best predictors of malignancy.

Keywords:
adnexal masses / Doppler / malignancy / ultrasound / ultrasound pattern recognition
Source:
Journal of BUON, 2015, 20, 3, 862-869
Publisher:
  • Balkan Union of Oncology (B.U.ON.)
Funding / projects:
  • Regenerative and modulatory potential of adult stem cells (RS-175062)

ISSN: 1107-0625

PubMed: 26214641

WoS: 000358399700025

[ Google Scholar ]
4
Handle
https://hdl.handle.net/21.15107/rcub_rimi_675
URI
http://rimi.imi.bg.ac.rs/handle/123456789/675
Collections
  • Radovi istraživača / Researchers' publications
Institution/Community
Institut za medicinska istraživanja
TY  - JOUR
AU  - Terzić, Milan
AU  - Dotlić, Jelena
AU  - Bila, Jovan
AU  - Pilić, Igor
AU  - Nikolić, Branka
AU  - Kocijancić, Dušica
AU  - Likić, Ivana
AU  - Arsenović, Nebojša
AU  - Mihailović, Tihomir
AU  - Bugarski, Diana
PY  - 2015
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/675
AB  - Purpose: To evaluate the reliability of ultrasound scan (US) findings in the preoperative assessment of the nature of adnexal masses in females. Methods: After detailed history, a preoperative US examination was performed in all women. Tumor diameter, localization, the presence of solid, cystic and multilocular components, excrescences, metastasis and free fluid were assessed. Doppler scan was done and pulsatility (PI) and resistance indices (RI) were determined. These data were compared with postoperatively obtained histo pathological findings and statistically analyzed. Results: The study included 609 women out of which 20.7% had malignant, 73.7% benign, and 5.6% borderline tumors. Patients with malignant tumors were oldest (p  lt 0.001). There were significantly more positive US parameters in malignant than in benign tumors (p lt 0.001). Also, there were significant differences (p lt 0.001) between malignant, benign and borderline tumors regarding all examined US and Doppler parameters except tumor multilocularity. RI had sensitivity 75%, specificity 61.2%, positive predictive value (PPV) 42.70% and negative predictive value (NPV) 96.16%. PI had sensitivity 50%, specificity 35.3%, PPV 8.37% and NPV 25.93%. Sensitivity of US characteristics was 94.34%, specificity 30.62%. PPV 22.27% and NPV 96.25%. Conclusions: US pattern characteristics and Doppler parameters were found to be moderately reliable in discriminating malignant, benign and borderline adnexal tumors. Tumor of solid or mixed consistency, presence of ascites and excrescences were the best predictors of malignancy.
PB  - Balkan Union of Oncology (B.U.ON.)
T2  - Journal of BUON
T1  - Utilization of ultrasound as a diagnostic tool in the preoperative assessment of patients with adnexal masses
EP  - 869
IS  - 3
SP  - 862
VL  - 20
UR  - conv_3549
ER  - 
@article{
author = "Terzić, Milan and Dotlić, Jelena and Bila, Jovan and Pilić, Igor and Nikolić, Branka and Kocijancić, Dušica and Likić, Ivana and Arsenović, Nebojša and Mihailović, Tihomir and Bugarski, Diana",
year = "2015",
abstract = "Purpose: To evaluate the reliability of ultrasound scan (US) findings in the preoperative assessment of the nature of adnexal masses in females. Methods: After detailed history, a preoperative US examination was performed in all women. Tumor diameter, localization, the presence of solid, cystic and multilocular components, excrescences, metastasis and free fluid were assessed. Doppler scan was done and pulsatility (PI) and resistance indices (RI) were determined. These data were compared with postoperatively obtained histo pathological findings and statistically analyzed. Results: The study included 609 women out of which 20.7% had malignant, 73.7% benign, and 5.6% borderline tumors. Patients with malignant tumors were oldest (p  lt 0.001). There were significantly more positive US parameters in malignant than in benign tumors (p lt 0.001). Also, there were significant differences (p lt 0.001) between malignant, benign and borderline tumors regarding all examined US and Doppler parameters except tumor multilocularity. RI had sensitivity 75%, specificity 61.2%, positive predictive value (PPV) 42.70% and negative predictive value (NPV) 96.16%. PI had sensitivity 50%, specificity 35.3%, PPV 8.37% and NPV 25.93%. Sensitivity of US characteristics was 94.34%, specificity 30.62%. PPV 22.27% and NPV 96.25%. Conclusions: US pattern characteristics and Doppler parameters were found to be moderately reliable in discriminating malignant, benign and borderline adnexal tumors. Tumor of solid or mixed consistency, presence of ascites and excrescences were the best predictors of malignancy.",
publisher = "Balkan Union of Oncology (B.U.ON.)",
journal = "Journal of BUON",
title = "Utilization of ultrasound as a diagnostic tool in the preoperative assessment of patients with adnexal masses",
pages = "869-862",
number = "3",
volume = "20",
url = "conv_3549"
}
Terzić, M., Dotlić, J., Bila, J., Pilić, I., Nikolić, B., Kocijancić, D., Likić, I., Arsenović, N., Mihailović, T.,& Bugarski, D.. (2015). Utilization of ultrasound as a diagnostic tool in the preoperative assessment of patients with adnexal masses. in Journal of BUON
Balkan Union of Oncology (B.U.ON.)., 20(3), 862-869.
conv_3549
Terzić M, Dotlić J, Bila J, Pilić I, Nikolić B, Kocijancić D, Likić I, Arsenović N, Mihailović T, Bugarski D. Utilization of ultrasound as a diagnostic tool in the preoperative assessment of patients with adnexal masses. in Journal of BUON. 2015;20(3):862-869.
conv_3549 .
Terzić, Milan, Dotlić, Jelena, Bila, Jovan, Pilić, Igor, Nikolić, Branka, Kocijancić, Dušica, Likić, Ivana, Arsenović, Nebojša, Mihailović, Tihomir, Bugarski, Diana, "Utilization of ultrasound as a diagnostic tool in the preoperative assessment of patients with adnexal masses" in Journal of BUON, 20, no. 3 (2015):862-869,
conv_3549 .

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