Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells
Апстракт
Adult stem cells have a great potential applicability in regenerative medicine and cell-based therapies. However, there are still many unresolved issues concerning their biology, and the influence of the local microenvironment on properties of stem cells has been increasingly recognized. Interleukin (IL-) 17, as a cytokine implicated in many physiological and pathological processes, should be taken into consideration as a part of a regulatory network governing tissue-associated stem cells' fate. This review is focusing on the published data on the effects of IL-17 on the properties and function of hematopoietic and mesenchymal stem cells and trying to discuss that IL-17 achieves many of its roles by acting on adult stem cells.
Извор:
Mediators of Inflammation, 2015, 2015Издавач:
- Hindawi Ltd, London
Финансирање / пројекти:
DOI: 10.1155/2015/470458
ISSN: 0962-9351
PubMed: 25999667
WoS: 000354330600001
Scopus: 2-s2.0-84929353586
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Mojsilović, Slavko AU - Jauković, Aleksandra AU - Santibanez, Juan AU - Bugarski, Diana PY - 2015 UR - http://rimi.imi.bg.ac.rs/handle/123456789/672 AB - Adult stem cells have a great potential applicability in regenerative medicine and cell-based therapies. However, there are still many unresolved issues concerning their biology, and the influence of the local microenvironment on properties of stem cells has been increasingly recognized. Interleukin (IL-) 17, as a cytokine implicated in many physiological and pathological processes, should be taken into consideration as a part of a regulatory network governing tissue-associated stem cells' fate. This review is focusing on the published data on the effects of IL-17 on the properties and function of hematopoietic and mesenchymal stem cells and trying to discuss that IL-17 achieves many of its roles by acting on adult stem cells. PB - Hindawi Ltd, London T2 - Mediators of Inflammation T1 - Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells VL - 2015 DO - 10.1155/2015/470458 ER -
@article{ author = "Mojsilović, Slavko and Jauković, Aleksandra and Santibanez, Juan and Bugarski, Diana", year = "2015", abstract = "Adult stem cells have a great potential applicability in regenerative medicine and cell-based therapies. However, there are still many unresolved issues concerning their biology, and the influence of the local microenvironment on properties of stem cells has been increasingly recognized. Interleukin (IL-) 17, as a cytokine implicated in many physiological and pathological processes, should be taken into consideration as a part of a regulatory network governing tissue-associated stem cells' fate. This review is focusing on the published data on the effects of IL-17 on the properties and function of hematopoietic and mesenchymal stem cells and trying to discuss that IL-17 achieves many of its roles by acting on adult stem cells.", publisher = "Hindawi Ltd, London", journal = "Mediators of Inflammation", title = "Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells", volume = "2015", doi = "10.1155/2015/470458" }
Mojsilović, S., Jauković, A., Santibanez, J.,& Bugarski, D.. (2015). Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells. in Mediators of Inflammation Hindawi Ltd, London., 2015. https://doi.org/10.1155/2015/470458
Mojsilović S, Jauković A, Santibanez J, Bugarski D. Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells. in Mediators of Inflammation. 2015;2015. doi:10.1155/2015/470458 .
Mojsilović, Slavko, Jauković, Aleksandra, Santibanez, Juan, Bugarski, Diana, "Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells" in Mediators of Inflammation, 2015 (2015), https://doi.org/10.1155/2015/470458 . .