Adult stem cells have a great potential applicability in regenerative medicine and cell-based therapies. However, there are still many unresolved issues concerning their biology, and the influence of the local microenvironment on properties of stem cells has been increasingly recognized. Interleukin (IL-) 17, as a cytokine implicated in many physiological and pathological processes, should be taken into consideration as a part of a regulatory network governing tissue-associated stem cells' fate. This review is focusing on the published data on the effects of IL-17 on the properties and function of hematopoietic and mesenchymal stem cells and trying to discuss that IL-17 achieves many of its roles by acting on adult stem cells.
TY - JOUR
AU - Mojsilović, Slavko
AU - Jauković, Aleksandra
AU - Santibanez, Juan
AU - Bugarski, Diana
PY - 2015
UR - http://rimi.imi.bg.ac.rs/handle/123456789/672
AB - Adult stem cells have a great potential applicability in regenerative medicine and cell-based therapies. However, there are still many unresolved issues concerning their biology, and the influence of the local microenvironment on properties of stem cells has been increasingly recognized. Interleukin (IL-) 17, as a cytokine implicated in many physiological and pathological processes, should be taken into consideration as a part of a regulatory network governing tissue-associated stem cells' fate. This review is focusing on the published data on the effects of IL-17 on the properties and function of hematopoietic and mesenchymal stem cells and trying to discuss that IL-17 achieves many of its roles by acting on adult stem cells.
PB - Hindawi Ltd, London
T2 - Mediators of Inflammation
T1 - Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells
VL - 2015
DO - 10.1155/2015/470458
ER -
@article{
author = "Mojsilović, Slavko and Jauković, Aleksandra and Santibanez, Juan and Bugarski, Diana",
year = "2015",
abstract = "Adult stem cells have a great potential applicability in regenerative medicine and cell-based therapies. However, there are still many unresolved issues concerning their biology, and the influence of the local microenvironment on properties of stem cells has been increasingly recognized. Interleukin (IL-) 17, as a cytokine implicated in many physiological and pathological processes, should be taken into consideration as a part of a regulatory network governing tissue-associated stem cells' fate. This review is focusing on the published data on the effects of IL-17 on the properties and function of hematopoietic and mesenchymal stem cells and trying to discuss that IL-17 achieves many of its roles by acting on adult stem cells.",
publisher = "Hindawi Ltd, London",
journal = "Mediators of Inflammation",
title = "Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells",
volume = "2015",
doi = "10.1155/2015/470458"
}
Mojsilović, S., Jauković, A., Santibanez, J.,& Bugarski, D.. (2015). Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells. in Mediators of Inflammation
Hindawi Ltd, London., 2015.
https://doi.org/10.1155/2015/470458
Mojsilović S, Jauković A, Santibanez J, Bugarski D. Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells. in Mediators of Inflammation. 2015;2015.
doi:10.1155/2015/470458 .
Mojsilović, Slavko, Jauković, Aleksandra, Santibanez, Juan, Bugarski, Diana, "Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells" in Mediators of Inflammation, 2015 (2015),
https://doi.org/10.1155/2015/470458 . .
