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Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells

Thumbnail
2015
669.pdf (1.710Mb)
Authors
Mojsilović, Slavko
Jauković, Aleksandra
Santibanez, Juan
Bugarski, Diana
Article (Published version)
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Abstract
Adult stem cells have a great potential applicability in regenerative medicine and cell-based therapies. However, there are still many unresolved issues concerning their biology, and the influence of the local microenvironment on properties of stem cells has been increasingly recognized. Interleukin (IL-) 17, as a cytokine implicated in many physiological and pathological processes, should be taken into consideration as a part of a regulatory network governing tissue-associated stem cells' fate. This review is focusing on the published data on the effects of IL-17 on the properties and function of hematopoietic and mesenchymal stem cells and trying to discuss that IL-17 achieves many of its roles by acting on adult stem cells.
Source:
Mediators of Inflammation, 2015, 2015
Publisher:
  • Hindawi Ltd, London
Funding / projects:
  • Regenerative and modulatory potential of adult stem cells (RS-175062)

DOI: 10.1155/2015/470458

ISSN: 0962-9351

PubMed: 25999667

WoS: 000354330600001

Scopus: 2-s2.0-84929353586
[ Google Scholar ]
22
15
URI
http://rimi.imi.bg.ac.rs/handle/123456789/672
Collections
  • Radovi istraživača / Researchers' publications
Institution/Community
Institut za medicinska istraživanja
TY  - JOUR
AU  - Mojsilović, Slavko
AU  - Jauković, Aleksandra
AU  - Santibanez, Juan
AU  - Bugarski, Diana
PY  - 2015
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/672
AB  - Adult stem cells have a great potential applicability in regenerative medicine and cell-based therapies. However, there are still many unresolved issues concerning their biology, and the influence of the local microenvironment on properties of stem cells has been increasingly recognized. Interleukin (IL-) 17, as a cytokine implicated in many physiological and pathological processes, should be taken into consideration as a part of a regulatory network governing tissue-associated stem cells' fate. This review is focusing on the published data on the effects of IL-17 on the properties and function of hematopoietic and mesenchymal stem cells and trying to discuss that IL-17 achieves many of its roles by acting on adult stem cells.
PB  - Hindawi Ltd, London
T2  - Mediators of Inflammation
T1  - Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells
VL  - 2015
DO  - 10.1155/2015/470458
UR  - conv_3491
ER  - 
@article{
author = "Mojsilović, Slavko and Jauković, Aleksandra and Santibanez, Juan and Bugarski, Diana",
year = "2015",
abstract = "Adult stem cells have a great potential applicability in regenerative medicine and cell-based therapies. However, there are still many unresolved issues concerning their biology, and the influence of the local microenvironment on properties of stem cells has been increasingly recognized. Interleukin (IL-) 17, as a cytokine implicated in many physiological and pathological processes, should be taken into consideration as a part of a regulatory network governing tissue-associated stem cells' fate. This review is focusing on the published data on the effects of IL-17 on the properties and function of hematopoietic and mesenchymal stem cells and trying to discuss that IL-17 achieves many of its roles by acting on adult stem cells.",
publisher = "Hindawi Ltd, London",
journal = "Mediators of Inflammation",
title = "Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells",
volume = "2015",
doi = "10.1155/2015/470458",
url = "conv_3491"
}
Mojsilović, S., Jauković, A., Santibanez, J.,& Bugarski, D.. (2015). Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells. in Mediators of Inflammation
Hindawi Ltd, London., 2015.
https://doi.org/10.1155/2015/470458
conv_3491
Mojsilović S, Jauković A, Santibanez J, Bugarski D. Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells. in Mediators of Inflammation. 2015;2015.
doi:10.1155/2015/470458
conv_3491 .
Mojsilović, Slavko, Jauković, Aleksandra, Santibanez, Juan, Bugarski, Diana, "Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells" in Mediators of Inflammation, 2015 (2015),
https://doi.org/10.1155/2015/470458 .,
conv_3491 .

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