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dc.creatorRistić-Medić, Danijela
dc.creatorPeruničić-Peković, Gordana
dc.creatorRašić-Milutinović, Zorica
dc.creatorTakić, Marija
dc.creatorPopović, Tamara B.
dc.creatorArsić, Aleksandra
dc.creatorGlibetić, Marija
dc.date.accessioned2021-04-20T12:40:51Z
dc.date.available2021-04-20T12:40:51Z
dc.date.issued2014
dc.identifier.issn1537-744X
dc.identifier.urihttp://rimi.imi.bg.ac.rs/handle/123456789/597
dc.description.abstractBackground. Plant seeds have gained interest for their health benefits due to their fatty acid content. The objective of this study was to determine the effects of dietary consumption of milled sesame/pumpkin/flax seed mixture on glycemic control, serum lipids, phospholipid fatty acid status, and inflammatory factors in patients on hemodialysis. Methods. Thirty patients with well nutrition status (18 male, 12 female) were enrolled in the study. Participants consumed 30 g of milled sesame/pumpkin/flax (6 g/6 g/18 g, resp.) seeds mixture added to their habitual diet. Results. Total n-6 and n-3 polyunsaturated fatty acids and levels of linoleic, dihomo-gamma-linolenic (DGLA), arachidonic, alpha-linolenic (ALA), eicosapentaenoic, docosapentaenoic, and docosahexaenoic (DHA) acid were increased after 12 weeks of supplementation. A significant decrease of the serum triglyceride level (P lt 0.001), glucose, insulin, calculated IR HOMA (P lt 0.05), and inflammatory markers (TNF-alpha, IL-6, and hs-CRP,P lt 0.001) was observed after seed mixture treatment. The serum levels of CRP and TNF-alpha negative correlate with ALA, DHA, and DGLA. Conclusion. Results of this study indicated that dietary milled sesame/pumpkin/flax seed mixture added to a habitual diet lowered triglyceride and CRP, TNF-alpha, IL-6 levels, affect glycemic control and improved fatty acid profile and pruritus symptoms in hemodialysis patients.en
dc.publisherHindawi Ltd, London
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41030/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceScientific World Journal
dc.titleEffects of Dietary Milled Seed Mixture on Fatty Acid Status and Inflammatory Markers in Patients on Hemodialysisen
dc.typearticle
dc.rights.licenseBY
dc.identifier.doi10.1155/2014/563576
dc.identifier.fulltexthttp://rimi.imi.bg.ac.rs/bitstream/id/458/594.pdf
dc.identifier.pmid24578648
dc.identifier.scopus2-s2.0-84893858441
dc.identifier.wos000330656900001
dc.type.versionpublishedVersion


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