Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats

2013
Authors
Durendic-Brenesel, MajaPopović, Tamara B.

Pilija, Vladimir
Arsić, Aleksandra Č.

Milić, Miljan
Kojić, Danijela

Jojić, Nikola
Milić, Nataša
Article (Published version)
Publisher's own license
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As a source of biologically active compounds, buckwheat has beneficial effects in nutrition due to its high content of flavonoids, particularly rutin. Aim of our study was to examine effects of buckwheat on plasma lipid status and phospholipids fatty acids composition, histological and parameters of oxidative stress in Wistar rats fed a high-fat diet. This study showed that buckwheat leaf and flower (BLF) mixture supplementation significantly reduce weight gain, plasma lipid concentrations and atherogenic index in rats fed a high-fat diet. Treatment of the high-fat group of animals with buckwheat significantly increased percentage of n-6 fatty acids as well as eicosapentaenoic acid (EPA) and decreased percentage of saturated fatty acids (SPA) and oleic acid. Buckwheat antioxidant effects diminished negative influence of high-fat diet in hyperlipidemic rats, while pathohistological analysis of liver confirmed changes after high-fat consumption. Our results showed hypolipidemic, antiathe...rogenic and antioxidative features of buckwheat leaf and flower mixture, and these parts of the plant with the highest rutin content could be beneficial in prevention and curing of hyperlipidemia.
Keywords:
buckwheat / plasma lipids / plasma phospholipids fatty acids / oxidative stress / hypolipidemic effectSource:
Bosnian Journal of Basic Medical Sciences, 2013, 13, 2, 100-108Publisher:
- Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, Cekalusa
Funding / projects:
DOI: 10.17305/bjbms.2013.2389
ISSN: 1512-8601
PubMed: 23725506
WoS: 000330925000007
Scopus: 2-s2.0-84883795107
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Institut za medicinska istraživanjaTY - JOUR AU - Durendic-Brenesel, Maja AU - Popović, Tamara B. AU - Pilija, Vladimir AU - Arsić, Aleksandra Č. AU - Milić, Miljan AU - Kojić, Danijela AU - Jojić, Nikola AU - Milić, Nataša PY - 2013 UR - http://rimi.imi.bg.ac.rs/handle/123456789/500 AB - As a source of biologically active compounds, buckwheat has beneficial effects in nutrition due to its high content of flavonoids, particularly rutin. Aim of our study was to examine effects of buckwheat on plasma lipid status and phospholipids fatty acids composition, histological and parameters of oxidative stress in Wistar rats fed a high-fat diet. This study showed that buckwheat leaf and flower (BLF) mixture supplementation significantly reduce weight gain, plasma lipid concentrations and atherogenic index in rats fed a high-fat diet. Treatment of the high-fat group of animals with buckwheat significantly increased percentage of n-6 fatty acids as well as eicosapentaenoic acid (EPA) and decreased percentage of saturated fatty acids (SPA) and oleic acid. Buckwheat antioxidant effects diminished negative influence of high-fat diet in hyperlipidemic rats, while pathohistological analysis of liver confirmed changes after high-fat consumption. Our results showed hypolipidemic, antiatherogenic and antioxidative features of buckwheat leaf and flower mixture, and these parts of the plant with the highest rutin content could be beneficial in prevention and curing of hyperlipidemia. PB - Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, Cekalusa T2 - Bosnian Journal of Basic Medical Sciences T1 - Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats EP - 108 IS - 2 SP - 100 VL - 13 DO - 10.17305/bjbms.2013.2389 UR - conv_2848 ER -
@article{ author = "Durendic-Brenesel, Maja and Popović, Tamara B. and Pilija, Vladimir and Arsić, Aleksandra Č. and Milić, Miljan and Kojić, Danijela and Jojić, Nikola and Milić, Nataša", year = "2013", abstract = "As a source of biologically active compounds, buckwheat has beneficial effects in nutrition due to its high content of flavonoids, particularly rutin. Aim of our study was to examine effects of buckwheat on plasma lipid status and phospholipids fatty acids composition, histological and parameters of oxidative stress in Wistar rats fed a high-fat diet. This study showed that buckwheat leaf and flower (BLF) mixture supplementation significantly reduce weight gain, plasma lipid concentrations and atherogenic index in rats fed a high-fat diet. Treatment of the high-fat group of animals with buckwheat significantly increased percentage of n-6 fatty acids as well as eicosapentaenoic acid (EPA) and decreased percentage of saturated fatty acids (SPA) and oleic acid. Buckwheat antioxidant effects diminished negative influence of high-fat diet in hyperlipidemic rats, while pathohistological analysis of liver confirmed changes after high-fat consumption. Our results showed hypolipidemic, antiatherogenic and antioxidative features of buckwheat leaf and flower mixture, and these parts of the plant with the highest rutin content could be beneficial in prevention and curing of hyperlipidemia.", publisher = "Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, Cekalusa", journal = "Bosnian Journal of Basic Medical Sciences", title = "Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats", pages = "108-100", number = "2", volume = "13", doi = "10.17305/bjbms.2013.2389", url = "conv_2848" }
Durendic-Brenesel, M., Popović, T. B., Pilija, V., Arsić, A. Č., Milić, M., Kojić, D., Jojić, N.,& Milić, N.. (2013). Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats. in Bosnian Journal of Basic Medical Sciences Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, Cekalusa., 13(2), 100-108. https://doi.org/10.17305/bjbms.2013.2389 conv_2848
Durendic-Brenesel M, Popović TB, Pilija V, Arsić AČ, Milić M, Kojić D, Jojić N, Milić N. Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats. in Bosnian Journal of Basic Medical Sciences. 2013;13(2):100-108. doi:10.17305/bjbms.2013.2389 conv_2848 .
Durendic-Brenesel, Maja, Popović, Tamara B., Pilija, Vladimir, Arsić, Aleksandra Č., Milić, Miljan, Kojić, Danijela, Jojić, Nikola, Milić, Nataša, "Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats" in Bosnian Journal of Basic Medical Sciences, 13, no. 2 (2013):100-108, https://doi.org/10.17305/bjbms.2013.2389 ., conv_2848 .