Effects of non-thermal atmospheric plasma on human periodontal ligament mesenchymal stem cells
Нема приказа
Аутори
Miletić, MajaMojsilović, S.
Okić Đorđević, Ivana
Maletić, Dejan
Puač, Nevena
Lazović, Saša
Malović, Gordana
Milenković, P.
Petrović, Zoran Lj.
Bugarski, Diana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Here we investigate the influences of non-thermal atmospheric plasma on human mesenchymal stem cells isolated from periodontal ligament (hPDL-MSCs). A specially redesigned plasma needle was used as the source of low-temperature plasma and its effects on different hPDL-MSC functions were investigated. Cell cultures were obtained from extracted normal impacted third molars and characterized for their phenotype and multi-potential differentiation. The hPDL-MSCs possessed all the typical MSC properties, including clonogenic ability, high proliferation rate, specific phenotype and multilineage differentiation. The data regarding the interaction of plasma with hPDL-MSCs demonstrated that plasma treatment inhibited the migration of hPDL-MSCs and induced some detachment, while not affecting their viability. Additionally, plasma significantly attenuated hPDL-MSCs' proliferation, but promoted their osteogenic differentiation. The results of this study indicated that a non-thermal plasma offers s...pecific activity with non-destructive properties that can be advantageous for future dental applications.
Извор:
Journal of Physics D-Applied Physics, 2013, 46, 34Издавач:
- Iop Publishing Ltd, Bristol
Финансирање / пројекти:
- Регенеративни и модулаторни потенцијал адултних матичних ћелија (RS-175062)
- Фундаментални процеси и примене транспорта честица у неравнотежним плазмама, траповима и наноструктурама (RS-171037)
- Примене нискотемпературних плазми у биомедицини, заштити човекове околине и нанотехнологијама (RS-41011)
DOI: 10.1088/0022-3727/46/34/345401
ISSN: 0022-3727
WoS: 000323062400017
Scopus: 2-s2.0-84882360715
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Miletić, Maja AU - Mojsilović, S. AU - Okić Đorđević, Ivana AU - Maletić, Dejan AU - Puač, Nevena AU - Lazović, Saša AU - Malović, Gordana AU - Milenković, P. AU - Petrović, Zoran Lj. AU - Bugarski, Diana PY - 2013 UR - http://rimi.imi.bg.ac.rs/handle/123456789/487 AB - Here we investigate the influences of non-thermal atmospheric plasma on human mesenchymal stem cells isolated from periodontal ligament (hPDL-MSCs). A specially redesigned plasma needle was used as the source of low-temperature plasma and its effects on different hPDL-MSC functions were investigated. Cell cultures were obtained from extracted normal impacted third molars and characterized for their phenotype and multi-potential differentiation. The hPDL-MSCs possessed all the typical MSC properties, including clonogenic ability, high proliferation rate, specific phenotype and multilineage differentiation. The data regarding the interaction of plasma with hPDL-MSCs demonstrated that plasma treatment inhibited the migration of hPDL-MSCs and induced some detachment, while not affecting their viability. Additionally, plasma significantly attenuated hPDL-MSCs' proliferation, but promoted their osteogenic differentiation. The results of this study indicated that a non-thermal plasma offers specific activity with non-destructive properties that can be advantageous for future dental applications. PB - Iop Publishing Ltd, Bristol T2 - Journal of Physics D-Applied Physics T1 - Effects of non-thermal atmospheric plasma on human periodontal ligament mesenchymal stem cells IS - 34 VL - 46 DO - 10.1088/0022-3727/46/34/345401 ER -
@article{ author = "Miletić, Maja and Mojsilović, S. and Okić Đorđević, Ivana and Maletić, Dejan and Puač, Nevena and Lazović, Saša and Malović, Gordana and Milenković, P. and Petrović, Zoran Lj. and Bugarski, Diana", year = "2013", abstract = "Here we investigate the influences of non-thermal atmospheric plasma on human mesenchymal stem cells isolated from periodontal ligament (hPDL-MSCs). A specially redesigned plasma needle was used as the source of low-temperature plasma and its effects on different hPDL-MSC functions were investigated. Cell cultures were obtained from extracted normal impacted third molars and characterized for their phenotype and multi-potential differentiation. The hPDL-MSCs possessed all the typical MSC properties, including clonogenic ability, high proliferation rate, specific phenotype and multilineage differentiation. The data regarding the interaction of plasma with hPDL-MSCs demonstrated that plasma treatment inhibited the migration of hPDL-MSCs and induced some detachment, while not affecting their viability. Additionally, plasma significantly attenuated hPDL-MSCs' proliferation, but promoted their osteogenic differentiation. The results of this study indicated that a non-thermal plasma offers specific activity with non-destructive properties that can be advantageous for future dental applications.", publisher = "Iop Publishing Ltd, Bristol", journal = "Journal of Physics D-Applied Physics", title = "Effects of non-thermal atmospheric plasma on human periodontal ligament mesenchymal stem cells", number = "34", volume = "46", doi = "10.1088/0022-3727/46/34/345401" }
Miletić, M., Mojsilović, S., Okić Đorđević, I., Maletić, D., Puač, N., Lazović, S., Malović, G., Milenković, P., Petrović, Z. Lj.,& Bugarski, D.. (2013). Effects of non-thermal atmospheric plasma on human periodontal ligament mesenchymal stem cells. in Journal of Physics D-Applied Physics Iop Publishing Ltd, Bristol., 46(34). https://doi.org/10.1088/0022-3727/46/34/345401
Miletić M, Mojsilović S, Okić Đorđević I, Maletić D, Puač N, Lazović S, Malović G, Milenković P, Petrović ZL, Bugarski D. Effects of non-thermal atmospheric plasma on human periodontal ligament mesenchymal stem cells. in Journal of Physics D-Applied Physics. 2013;46(34). doi:10.1088/0022-3727/46/34/345401 .
Miletić, Maja, Mojsilović, S., Okić Đorđević, Ivana, Maletić, Dejan, Puač, Nevena, Lazović, Saša, Malović, Gordana, Milenković, P., Petrović, Zoran Lj., Bugarski, Diana, "Effects of non-thermal atmospheric plasma on human periodontal ligament mesenchymal stem cells" in Journal of Physics D-Applied Physics, 46, no. 34 (2013), https://doi.org/10.1088/0022-3727/46/34/345401 . .