A systematic review was conducted to summarize the evidence currently available from randomized controlled trials (RCTs) concerning the effect of iron intake of infants, children and adolescents on measures of cognitive development and function. The Cochrane Library, MEDLINE and Embase were searched up to and including February 2010. Studies were also identified by checking the bibliographies of the articles retrieved. All RCTs with an adequate control group in which iron supply was provided by natural food sources, fortified foods, formula or supplements to infants, children or adolescents until the age of 18 years were considered for inclusion. No language restrictions were applied. Fourteen studies met the selection criteria. Twelve out of these 14 studies had a high or moderate risk of bias. A large degree of heterogeneity of study populations, iron dosages and outcome measures precluded performing a quantitative meta-analysis. Overall, the studies suggest a modest positive effect ...of iron supplementation on cognition and psychomotor outcomes in anemic infants and children after supplementation periods of at least 2 months of duration. Copyright (C) 2011 S. Karger AG, Basel
Keywords:
Iron requirements / Cognition / Infants / Children / Adolescents / EURRECA
Source:
Annals of Nutrition & Metabolism, 2011, 59, 2-4, 154-165
Publisher:
Karger, Basel
Funding / projects:
Commission of the European Communities, specific RTD Programme "Quality of Life and Management of Living Resources," 6th Framework Programme [FP6-036196-2]
Bristol Myers Squibb Foundation, New York, N.Y., USABristol-Myers Squibb
TY - JOUR
AU - Hermoso, Maria
AU - Vučić, Vesna M.
AU - Vollhardt, Christiane
AU - Arsić, Aleksandra Č.
AU - Roman-Vinas, Blanca
AU - Iglesia-Altaba, Iris
AU - Gurinović, Mirjana A.
AU - Koletzko, Berthold
PY - 2011
UR - http://rimi.imi.bg.ac.rs/handle/123456789/351
AB - A systematic review was conducted to summarize the evidence currently available from randomized controlled trials (RCTs) concerning the effect of iron intake of infants, children and adolescents on measures of cognitive development and function. The Cochrane Library, MEDLINE and Embase were searched up to and including February 2010. Studies were also identified by checking the bibliographies of the articles retrieved. All RCTs with an adequate control group in which iron supply was provided by natural food sources, fortified foods, formula or supplements to infants, children or adolescents until the age of 18 years were considered for inclusion. No language restrictions were applied. Fourteen studies met the selection criteria. Twelve out of these 14 studies had a high or moderate risk of bias. A large degree of heterogeneity of study populations, iron dosages and outcome measures precluded performing a quantitative meta-analysis. Overall, the studies suggest a modest positive effect of iron supplementation on cognition and psychomotor outcomes in anemic infants and children after supplementation periods of at least 2 months of duration. Copyright (C) 2011 S. Karger AG, Basel
PB - Karger, Basel
T2 - Annals of Nutrition & Metabolism
T1 - The Effect of Iron on Cognitive Development and Function in Infants, Children and Adolescents: A Systematic Review
EP - 165
IS - 2-4
SP - 154
VL - 59
DO - 10.1159/000334490
UR - conv_2665
ER -
@article{
author = "Hermoso, Maria and Vučić, Vesna M. and Vollhardt, Christiane and Arsić, Aleksandra Č. and Roman-Vinas, Blanca and Iglesia-Altaba, Iris and Gurinović, Mirjana A. and Koletzko, Berthold",
year = "2011",
abstract = "A systematic review was conducted to summarize the evidence currently available from randomized controlled trials (RCTs) concerning the effect of iron intake of infants, children and adolescents on measures of cognitive development and function. The Cochrane Library, MEDLINE and Embase were searched up to and including February 2010. Studies were also identified by checking the bibliographies of the articles retrieved. All RCTs with an adequate control group in which iron supply was provided by natural food sources, fortified foods, formula or supplements to infants, children or adolescents until the age of 18 years were considered for inclusion. No language restrictions were applied. Fourteen studies met the selection criteria. Twelve out of these 14 studies had a high or moderate risk of bias. A large degree of heterogeneity of study populations, iron dosages and outcome measures precluded performing a quantitative meta-analysis. Overall, the studies suggest a modest positive effect of iron supplementation on cognition and psychomotor outcomes in anemic infants and children after supplementation periods of at least 2 months of duration. Copyright (C) 2011 S. Karger AG, Basel",
publisher = "Karger, Basel",
journal = "Annals of Nutrition & Metabolism",
title = "The Effect of Iron on Cognitive Development and Function in Infants, Children and Adolescents: A Systematic Review",
pages = "165-154",
number = "2-4",
volume = "59",
doi = "10.1159/000334490",
url = "conv_2665"
}
Hermoso, M., Vučić, V. M., Vollhardt, C., Arsić, A. Č., Roman-Vinas, B., Iglesia-Altaba, I., Gurinović, M. A.,& Koletzko, B.. (2011). The Effect of Iron on Cognitive Development and Function in Infants, Children and Adolescents: A Systematic Review. in Annals of Nutrition & Metabolism
Karger, Basel., 59(2-4), 154-165.
https://doi.org/10.1159/000334490
conv_2665
Hermoso M, Vučić VM, Vollhardt C, Arsić AČ, Roman-Vinas B, Iglesia-Altaba I, Gurinović MA, Koletzko B. The Effect of Iron on Cognitive Development and Function in Infants, Children and Adolescents: A Systematic Review. in Annals of Nutrition & Metabolism. 2011;59(2-4):154-165.
doi:10.1159/000334490
conv_2665 .
Hermoso, Maria, Vučić, Vesna M., Vollhardt, Christiane, Arsić, Aleksandra Č., Roman-Vinas, Blanca, Iglesia-Altaba, Iris, Gurinović, Mirjana A., Koletzko, Berthold, "The Effect of Iron on Cognitive Development and Function in Infants, Children and Adolescents: A Systematic Review" in Annals of Nutrition & Metabolism, 59, no. 2-4 (2011):154-165,
https://doi.org/10.1159/000334490 .,
conv_2665 .
