In the present study we have isolated and identified mesenchymal stem cells (MSCs) from the exfoliated deciduous teeth dental pulp (DP-MSCs), as plastic-adherent, spindle-shaped cells with a high proliferative potential. Immunophenotype analyses revealed that DP-MSCs were positive for mesenchymal cell markers (CD90, CD44, CD105, STRO-1, vimentin and α-SMA), and negative for hematopoietic stem cell markers (CD11b, CD33, CD34, CD45, CD235a). DPMSCs were also capable of differentiating into adipogenic, chondrogenic, myogenic and osteogenic lineages, fulfilling the functional criterion for their characterization. These results demonstrate that DP-MSCs offer a valuable, readily accessible source to obtain and store adult stem cells for future use.
TY - JOUR
AU - Nikolić, N.
AU - Krstić, Aleksandra
AU - Trivanović, Drenka
AU - Mojsilović, S.
AU - Kocić, Jelena
AU - Santibanez, Juan
AU - Jovčić, Gordana
AU - Bugarski, Diana
PY - 2011
UR - http://rimi.imi.bg.ac.rs/handle/123456789/350
AB - In the present study we have isolated and identified mesenchymal stem cells (MSCs) from the exfoliated deciduous teeth dental pulp (DP-MSCs), as plastic-adherent, spindle-shaped cells with a high proliferative potential. Immunophenotype analyses revealed that DP-MSCs were positive for mesenchymal cell markers (CD90, CD44, CD105, STRO-1, vimentin and α-SMA), and negative for hematopoietic stem cell markers (CD11b, CD33, CD34, CD45, CD235a). DPMSCs were also capable of differentiating into adipogenic, chondrogenic, myogenic and osteogenic lineages, fulfilling the functional criterion for their characterization. These results demonstrate that DP-MSCs offer a valuable, readily accessible source to obtain and store adult stem cells for future use.
PB - Srpsko biološko društvo, Beograd, i dr.
T2 - Archives of Biological Sciences
T1 - Mesenchymal stem cell properties of dental pulp cells from deciduous teeth
EP - 942
IS - 4
SP - 933
VL - 63
DO - 10.2298/ABS1104933N
ER -
@article{
author = "Nikolić, N. and Krstić, Aleksandra and Trivanović, Drenka and Mojsilović, S. and Kocić, Jelena and Santibanez, Juan and Jovčić, Gordana and Bugarski, Diana",
year = "2011",
abstract = "In the present study we have isolated and identified mesenchymal stem cells (MSCs) from the exfoliated deciduous teeth dental pulp (DP-MSCs), as plastic-adherent, spindle-shaped cells with a high proliferative potential. Immunophenotype analyses revealed that DP-MSCs were positive for mesenchymal cell markers (CD90, CD44, CD105, STRO-1, vimentin and α-SMA), and negative for hematopoietic stem cell markers (CD11b, CD33, CD34, CD45, CD235a). DPMSCs were also capable of differentiating into adipogenic, chondrogenic, myogenic and osteogenic lineages, fulfilling the functional criterion for their characterization. These results demonstrate that DP-MSCs offer a valuable, readily accessible source to obtain and store adult stem cells for future use.",
publisher = "Srpsko biološko društvo, Beograd, i dr.",
journal = "Archives of Biological Sciences",
title = "Mesenchymal stem cell properties of dental pulp cells from deciduous teeth",
pages = "942-933",
number = "4",
volume = "63",
doi = "10.2298/ABS1104933N"
}
Nikolić, N., Krstić, A., Trivanović, D., Mojsilović, S., Kocić, J., Santibanez, J., Jovčić, G.,& Bugarski, D.. (2011). Mesenchymal stem cell properties of dental pulp cells from deciduous teeth. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd, i dr.., 63(4), 933-942.
https://doi.org/10.2298/ABS1104933N
conv_2666
Nikolić N, Krstić A, Trivanović D, Mojsilović S, Kocić J, Santibanez J, Jovčić G, Bugarski D. Mesenchymal stem cell properties of dental pulp cells from deciduous teeth. in Archives of Biological Sciences. 2011;63(4):933-942.
doi:10.2298/ABS1104933N
conv_2666 .
Nikolić, N., Krstić, Aleksandra, Trivanović, Drenka, Mojsilović, S., Kocić, Jelena, Santibanez, Juan, Jovčić, Gordana, Bugarski, Diana, "Mesenchymal stem cell properties of dental pulp cells from deciduous teeth" in Archives of Biological Sciences, 63, no. 4 (2011):933-942,
https://doi.org/10.2298/ABS1104933N .,
conv_2666 .
