Impairment of cortical inhibition in writer's cramp as revealed by changes in electromyographic silent period after transcranial magnetic stimulation
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1997
Authors
Filipović, Saša
Ljubisavljević, Miloš

Svetel, Marina
Milanović, Slađan

Kačar, Aleksandra
Kostić, Vladimir S.

Article (Published version)

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Changes in silent period (SP) duration following transcranial magnetic stimulation (TMS) set at 20% above the motor threshold were studied in six subjects suffering from writer's cramp, while performing dystonic movement and during voluntary isometric contraction of the muscles mostly involved in the dystonic movement. Dependency of SP duration on the intensity of preceding muscle contraction was compared on both affected and healthy side. In all subjects SP duration during dystonic contraction was shorter than during voluntary contraction of the similar strength performed with the same hand. Also, in five subjects, SP duration during dystonic contraction was shorter than during voluntary contraction of the similar strength performed with the healthy hand. In addition, the SP duration on the affected side was negatively associated with the intensity of the preceding contraction (i.e. the stronger contraction the shorter SP), while on the healthy side it was not the case. It is conclude...d that central inhibitory mechanisms are abnormal in writer's cramp.
Keywords:
transcranial magnetic stimulation / silent period / intracortical inhibition / focal dystonia / writer's crampSource:
Neuroscience Letters, 1997, 222, 3, 167-170Publisher:
- Elsevier Ireland Ltd, Clare
DOI: 10.1016/S0304-3940(97)13370-5
ISSN: 0304-3940
PubMed: 9148241
WoS: A1997WJ34000007
Scopus: 2-s2.0-0031042281
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Institut za medicinska istraživanjaTY - JOUR AU - Filipović, Saša AU - Ljubisavljević, Miloš AU - Svetel, Marina AU - Milanović, Slađan AU - Kačar, Aleksandra AU - Kostić, Vladimir S. PY - 1997 UR - http://rimi.imi.bg.ac.rs/handle/123456789/34 AB - Changes in silent period (SP) duration following transcranial magnetic stimulation (TMS) set at 20% above the motor threshold were studied in six subjects suffering from writer's cramp, while performing dystonic movement and during voluntary isometric contraction of the muscles mostly involved in the dystonic movement. Dependency of SP duration on the intensity of preceding muscle contraction was compared on both affected and healthy side. In all subjects SP duration during dystonic contraction was shorter than during voluntary contraction of the similar strength performed with the same hand. Also, in five subjects, SP duration during dystonic contraction was shorter than during voluntary contraction of the similar strength performed with the healthy hand. In addition, the SP duration on the affected side was negatively associated with the intensity of the preceding contraction (i.e. the stronger contraction the shorter SP), while on the healthy side it was not the case. It is concluded that central inhibitory mechanisms are abnormal in writer's cramp. PB - Elsevier Ireland Ltd, Clare T2 - Neuroscience Letters T1 - Impairment of cortical inhibition in writer's cramp as revealed by changes in electromyographic silent period after transcranial magnetic stimulation EP - 170 IS - 3 SP - 167 VL - 222 DO - 10.1016/S0304-3940(97)13370-5 ER -
@article{ author = "Filipović, Saša and Ljubisavljević, Miloš and Svetel, Marina and Milanović, Slađan and Kačar, Aleksandra and Kostić, Vladimir S.", year = "1997", abstract = "Changes in silent period (SP) duration following transcranial magnetic stimulation (TMS) set at 20% above the motor threshold were studied in six subjects suffering from writer's cramp, while performing dystonic movement and during voluntary isometric contraction of the muscles mostly involved in the dystonic movement. Dependency of SP duration on the intensity of preceding muscle contraction was compared on both affected and healthy side. In all subjects SP duration during dystonic contraction was shorter than during voluntary contraction of the similar strength performed with the same hand. Also, in five subjects, SP duration during dystonic contraction was shorter than during voluntary contraction of the similar strength performed with the healthy hand. In addition, the SP duration on the affected side was negatively associated with the intensity of the preceding contraction (i.e. the stronger contraction the shorter SP), while on the healthy side it was not the case. It is concluded that central inhibitory mechanisms are abnormal in writer's cramp.", publisher = "Elsevier Ireland Ltd, Clare", journal = "Neuroscience Letters", title = "Impairment of cortical inhibition in writer's cramp as revealed by changes in electromyographic silent period after transcranial magnetic stimulation", pages = "170-167", number = "3", volume = "222", doi = "10.1016/S0304-3940(97)13370-5" }
Filipović, S., Ljubisavljević, M., Svetel, M., Milanović, S., Kačar, A.,& Kostić, V. S.. (1997). Impairment of cortical inhibition in writer's cramp as revealed by changes in electromyographic silent period after transcranial magnetic stimulation. in Neuroscience Letters Elsevier Ireland Ltd, Clare., 222(3), 167-170. https://doi.org/10.1016/S0304-3940(97)13370-5
Filipović S, Ljubisavljević M, Svetel M, Milanović S, Kačar A, Kostić VS. Impairment of cortical inhibition in writer's cramp as revealed by changes in electromyographic silent period after transcranial magnetic stimulation. in Neuroscience Letters. 1997;222(3):167-170. doi:10.1016/S0304-3940(97)13370-5 .
Filipović, Saša, Ljubisavljević, Miloš, Svetel, Marina, Milanović, Slađan, Kačar, Aleksandra, Kostić, Vladimir S., "Impairment of cortical inhibition in writer's cramp as revealed by changes in electromyographic silent period after transcranial magnetic stimulation" in Neuroscience Letters, 222, no. 3 (1997):167-170, https://doi.org/10.1016/S0304-3940(97)13370-5 . .