A simple method to assess freezing of gait in Parkinson's disease patients

2010
Authors
Popović, M. B.Đurić-Jovičić, Milica
Radovanović, Saša M.

Petrović, Igor
Kostić, Vladimir S.

Article (Published version)
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Freezing of gait (FOG) can be assessed by clinical and instrumental methods. Clinical examination has the advantage of being available to most clinicians; however, it requires experience and may not reveal FOG even for cases confirmed by the medical history. Instrumental methods have an advantage in that they may be used for ambulatory monitoring. The aim of the present study was to describe and evaluate a new instrumental method based on a force sensitive resistor and Pearson's correlation coefficient (Pcc) for the assessment of FOG. Nine patients with Parkinson's disease in the "on" state walked through a corridor, passed through a doorway and made a U-turn. We analyzed 24 FOG episodes by computing the Pcc between one "regular/normal" step and the rest of the steps. The Pcc reached +/- 1 for "normal" locomotion, while correlation diminished due to the lack of periodicity during FOG episodes. Gait was assessed in parallel with video. FOG episodes determined from the video were all det...ected with the proposed method. The computed duration of the FOG episodes was compared with those estimated from the video. The method was sensitive to various types of freezing; although no differences due to different types of freezing were detected. The study showed that Pcc analysis permitted the computerized detection of FOG in a simple manner analogous to human visual judgment, and its automation may be useful in clinical practice to provide a record of the history of FOG.
Keywords:
Parkinson's disease / Freezing of gait / Time analysis / Pearson's correlation coefficientSource:
Brazilian Journal of Medical & Biological Research, 2010, 43, 9, 883-889Publisher:
- Assoc Bras Divulg Cientifica, Sao Paulo
Funding / projects:
- Danish National Research Foundation, Denmark
- Effects of assistive systems in neurorehabilitation: recovery of sensory-motor functions (RS-175016)
- Istraživanje karakteristika i definisanje narušenog obrasca hoda u degenerativnim bolestima (RS-156011)
- Istraživanje kliničkih i genetičkih korelacija motornih i nemotornih ispoljavanja bolesti nevoljnih pokreta (RS-145057)
DOI: 10.1590/S0100-879X2010007500077
ISSN: 0100-879X
PubMed: 20721472
WoS: 000283262800011
Scopus: 2-s2.0-77957045533
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Institut za medicinska istraživanjaTY - JOUR AU - Popović, M. B. AU - Đurić-Jovičić, Milica AU - Radovanović, Saša M. AU - Petrović, Igor AU - Kostić, Vladimir S. PY - 2010 UR - http://rimi.imi.bg.ac.rs/handle/123456789/279 AB - Freezing of gait (FOG) can be assessed by clinical and instrumental methods. Clinical examination has the advantage of being available to most clinicians; however, it requires experience and may not reveal FOG even for cases confirmed by the medical history. Instrumental methods have an advantage in that they may be used for ambulatory monitoring. The aim of the present study was to describe and evaluate a new instrumental method based on a force sensitive resistor and Pearson's correlation coefficient (Pcc) for the assessment of FOG. Nine patients with Parkinson's disease in the "on" state walked through a corridor, passed through a doorway and made a U-turn. We analyzed 24 FOG episodes by computing the Pcc between one "regular/normal" step and the rest of the steps. The Pcc reached +/- 1 for "normal" locomotion, while correlation diminished due to the lack of periodicity during FOG episodes. Gait was assessed in parallel with video. FOG episodes determined from the video were all detected with the proposed method. The computed duration of the FOG episodes was compared with those estimated from the video. The method was sensitive to various types of freezing; although no differences due to different types of freezing were detected. The study showed that Pcc analysis permitted the computerized detection of FOG in a simple manner analogous to human visual judgment, and its automation may be useful in clinical practice to provide a record of the history of FOG. PB - Assoc Bras Divulg Cientifica, Sao Paulo T2 - Brazilian Journal of Medical & Biological Research T1 - A simple method to assess freezing of gait in Parkinson's disease patients EP - 889 IS - 9 SP - 883 VL - 43 DO - 10.1590/S0100-879X2010007500077 ER -
@article{ author = "Popović, M. B. and Đurić-Jovičić, Milica and Radovanović, Saša M. and Petrović, Igor and Kostić, Vladimir S.", year = "2010", abstract = "Freezing of gait (FOG) can be assessed by clinical and instrumental methods. Clinical examination has the advantage of being available to most clinicians; however, it requires experience and may not reveal FOG even for cases confirmed by the medical history. Instrumental methods have an advantage in that they may be used for ambulatory monitoring. The aim of the present study was to describe and evaluate a new instrumental method based on a force sensitive resistor and Pearson's correlation coefficient (Pcc) for the assessment of FOG. Nine patients with Parkinson's disease in the "on" state walked through a corridor, passed through a doorway and made a U-turn. We analyzed 24 FOG episodes by computing the Pcc between one "regular/normal" step and the rest of the steps. The Pcc reached +/- 1 for "normal" locomotion, while correlation diminished due to the lack of periodicity during FOG episodes. Gait was assessed in parallel with video. FOG episodes determined from the video were all detected with the proposed method. The computed duration of the FOG episodes was compared with those estimated from the video. The method was sensitive to various types of freezing; although no differences due to different types of freezing were detected. The study showed that Pcc analysis permitted the computerized detection of FOG in a simple manner analogous to human visual judgment, and its automation may be useful in clinical practice to provide a record of the history of FOG.", publisher = "Assoc Bras Divulg Cientifica, Sao Paulo", journal = "Brazilian Journal of Medical & Biological Research", title = "A simple method to assess freezing of gait in Parkinson's disease patients", pages = "889-883", number = "9", volume = "43", doi = "10.1590/S0100-879X2010007500077" }
Popović, M. B., Đurić-Jovičić, M., Radovanović, S. M., Petrović, I.,& Kostić, V. S.. (2010). A simple method to assess freezing of gait in Parkinson's disease patients. in Brazilian Journal of Medical & Biological Research Assoc Bras Divulg Cientifica, Sao Paulo., 43(9), 883-889. https://doi.org/10.1590/S0100-879X2010007500077
Popović MB, Đurić-Jovičić M, Radovanović SM, Petrović I, Kostić VS. A simple method to assess freezing of gait in Parkinson's disease patients. in Brazilian Journal of Medical & Biological Research. 2010;43(9):883-889. doi:10.1590/S0100-879X2010007500077 .
Popović, M. B., Đurić-Jovičić, Milica, Radovanović, Saša M., Petrović, Igor, Kostić, Vladimir S., "A simple method to assess freezing of gait in Parkinson's disease patients" in Brazilian Journal of Medical & Biological Research, 43, no. 9 (2010):883-889, https://doi.org/10.1590/S0100-879X2010007500077 . .