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dc.creatorJevtović, Đorđe
dc.creatorSalemović, Dubravka
dc.creatorRanin, Jovan
dc.creatorBrmbolić, Branko
dc.creatorĐurković-Đaković, Olgica
dc.date.accessioned2021-04-20T12:18:18Z
dc.date.available2021-04-20T12:18:18Z
dc.date.issued2009
dc.identifier.issn1570-162X
dc.identifier.urihttp://rimi.imi.bg.ac.rs/handle/123456789/252
dc.description.abstractTo determine the outcome of HIV infection in children in a resource-limited setting, a retrospective analysis of a series of 51 pediatric cases from the Serbian cohort of HIV infected patients was performed. Twenty seven patients died in the pre-HAART era, but mono/dual antiretroviral treatment had significantly (p=0.046) prolonged survival. Of the total of 24 HAART-treated patients, 10 had clinical AIDS before HAART initiation. The mean baseline CD4 cell count was 193.9 +/- 170.0/mm(3). After a mean follow-up of 72.6 +/- 44 months, a favorable response was recorded in 62.5%, treatment failure (defined as non-achievement of undetectable viremia) in 20.8%, and a discrepant virological and immunological response (achievement of undetectable viremia but without a rise in CD4 cell counts adequate for age) in 16.7% patients. No patients died, and there were only three hospital admissions after commencing HAART. Five immune restoration inflammatory syndrome episodes were recorded, of which four were due to BCG-osis. Lipodystrophy and hyperlipidemia occurred in 18.2% and 26.3% patients, respectively. We conclude that even in suboptimal facilities, the prognosis of HIV disease among children on HAART may be rather good. The metabolic syndrome seems to emerge as an important issue among long-term surviving children on HAART.en
dc.publisherBentham Science Publ Ltd, Sharjah
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/145002/RS//
dc.rightsrestrictedAccess
dc.sourceCurrent HIV Research
dc.subjectPediatric HIV/AIDSen
dc.subjectHAARTen
dc.subjectPrognosisen
dc.titleThe Prognosis of Pediatric AIDS in Serbiaen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage292
dc.citation.issue3
dc.citation.other7(3): 287-292
dc.citation.rankM23
dc.citation.spage287
dc.citation.volume7
dc.identifier.doi10.2174/157016209788347912
dc.identifier.pmid19442124
dc.identifier.scopus2-s2.0-67649099433
dc.identifier.wos000267014100006
dc.type.versionpublishedVersion


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