Приказ основних података о документу

dc.creatorRistić-Medić, Danijela
dc.creatorPiskackova, Zlata
dc.creatorHooper, Lee
dc.creatorRuprich, Jiri
dc.creatorCasgrain, Amelie
dc.creatorAshton, Kate
dc.creatorPavlović, Mirjana
dc.creatorGlibetić, Marija
dc.date.accessioned2021-04-20T12:18:05Z
dc.date.available2021-04-20T12:18:05Z
dc.date.issued2009
dc.identifier.issn0002-9165
dc.identifier.urihttp://rimi.imi.bg.ac.rs/handle/123456789/249
dc.description.abstractBackground: Biomarkers of iodine status are required to study iodine deficiency disorders in different parts of the world and to evaluate the effects of fortification strategies. Objective: The objective was to assess the usefulness of biomarkers of iodine status in humans by systematically reviewing intervention studies that altered iodine status. Design: We performed a structured search for iodine intervention studies on Ovid MEDLINE, EMBASE (Ovid), and the Cochrane Library. Studies were assessed for inclusion and validity, with independent duplication. A random-effects meta-analysis was performed. Results: Twenty-one intervention studies (12 randomized controlled trials, 3 controlled clinical trials, and 6 before-after studies) were included in the review. Urinary iodine (in children and adolescents and in those with low and moderate baseline iodine status), thyroglobulin (in children and adolescents but not in pregnant and lactating women), serum thyroxine (in children and adolescents, adults, women, and those with moderate baseline thyroxine status but not in pregnant and lactating women), and serum thyroid-stimulating hormone (in pregnant and lactating women but not in children and adolescents or those at moderate baseline status), but not triiodothyronine, proved to be useful biomarkers of iodine status. Conclusions: Despite the high risk of bias of many of the included studies, the results suggested that urinary iodine, thyroglobin, serum thyroxine, and thyroid-stimulating hormone are useful biomarkers of iodine status, at least in some groups. High-quality controlled studies measuring relevant long-term outcomes are needed to address which biomarker is the most appropriate for assessing iodine intake in some population groups and settings. Am J Clin Nutr 2009; 89(suppl): 2052S-69S.en
dc.publisherOxford Univ Press, Oxford
dc.rightsopenAccess
dc.sourceAmerican Journal of Clinical Nutrition
dc.titleMethods of assessment of iodine status in humans: a systematic reviewen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage2069S
dc.citation.issue6
dc.citation.other89(6): 2052S-2069S
dc.citation.rankaM21
dc.citation.spage2052S
dc.citation.volume89
dc.identifier.doi10.3945/ajcn.2009.27230H
dc.identifier.fulltexthttp://rimi.imi.bg.ac.rs/bitstream/id/199/246.pdf
dc.identifier.pmid19420096
dc.identifier.scopus2-s2.0-66849131599
dc.identifier.wos000266245500047
dc.type.versionpublishedVersion


Документи

Thumbnail

Овај документ се појављује у следећим колекцијама

Приказ основних података о документу