Evolutionary dynamics and geographical dispersal of Borrelia lusitaniae
Аутори
Ćirković, ValentinaVeinović, Gorana
Stanković, Daliborka
Mihaljica, Darko
Sukara, Ratko
Tomanović, Snežana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Background: Borrelia lusitaniae is a species within the complex Borrelia burgdorferi sensu lato, associated with lizards as reservoirs and Ixodes ricinus as its main vector. Borrelia lusitaniae is predominantly distributed in Central and Southeast Europe, and in countries of the Mediterranean basin, such as Portugal, Morocco, Tunisia, and Italy where this spirochete appears to infect vector ticks more frequently than other genospecies. Evolution of this zoonotic tick-borne microparasite is shaped by different environmental factors. Comprehensive phylogenetic analysis may give insight into how B. lusitaniae spreads to new geographic locations. Aim: We applied Bayesian statistical methods to B. lusitaniae multilocus sequence typing (MLST) data to study the migration routes of B. lusitaniae and its potential for further spread. Results: The discrete phylogeographic analysis placed origins of B. lusitaniae in Southeast Europe and identified at least two introductions of B. lusitaniae fro...m Europe to North Africa. Estimated effective reproductive potential (Re), as a key indicator for a pathogen spread, suggested potential for further spread. Conclusion: The results of this study can provide beneficial information about the potential for further spread of B. lusitaniae in Europe and North Africa and estimation of necessity for the development of strategies to monitor and control Lyme borreliosis.
Кључне речи:
Borrelia lusitaniae / phylogeography / phylodynamic / migratory birds / Ixodes ricinus / lizardsИзвор:
Frontiers in Microbiology, 2024, 15, 1330914-Издавач:
- Frontiers Media SA
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200015 (Универзитет у Београду, Институт за медицинска истраживања) (RS-MESTD-inst-2020-200015)
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Ćirković, Valentina AU - Veinović, Gorana AU - Stanković, Daliborka AU - Mihaljica, Darko AU - Sukara, Ratko AU - Tomanović, Snežana PY - 2024 UR - http://rimi.imi.bg.ac.rs/handle/123456789/1465 AB - Background: Borrelia lusitaniae is a species within the complex Borrelia burgdorferi sensu lato, associated with lizards as reservoirs and Ixodes ricinus as its main vector. Borrelia lusitaniae is predominantly distributed in Central and Southeast Europe, and in countries of the Mediterranean basin, such as Portugal, Morocco, Tunisia, and Italy where this spirochete appears to infect vector ticks more frequently than other genospecies. Evolution of this zoonotic tick-borne microparasite is shaped by different environmental factors. Comprehensive phylogenetic analysis may give insight into how B. lusitaniae spreads to new geographic locations. Aim: We applied Bayesian statistical methods to B. lusitaniae multilocus sequence typing (MLST) data to study the migration routes of B. lusitaniae and its potential for further spread. Results: The discrete phylogeographic analysis placed origins of B. lusitaniae in Southeast Europe and identified at least two introductions of B. lusitaniae from Europe to North Africa. Estimated effective reproductive potential (Re), as a key indicator for a pathogen spread, suggested potential for further spread. Conclusion: The results of this study can provide beneficial information about the potential for further spread of B. lusitaniae in Europe and North Africa and estimation of necessity for the development of strategies to monitor and control Lyme borreliosis. PB - Frontiers Media SA T2 - Frontiers in Microbiology T2 - Frontiers in Microbiology T1 - Evolutionary dynamics and geographical dispersal of Borrelia lusitaniae SP - 1330914 VL - 15 DO - 10.3389/fmicb.2024.1330914 ER -
@article{ author = "Ćirković, Valentina and Veinović, Gorana and Stanković, Daliborka and Mihaljica, Darko and Sukara, Ratko and Tomanović, Snežana", year = "2024", abstract = "Background: Borrelia lusitaniae is a species within the complex Borrelia burgdorferi sensu lato, associated with lizards as reservoirs and Ixodes ricinus as its main vector. Borrelia lusitaniae is predominantly distributed in Central and Southeast Europe, and in countries of the Mediterranean basin, such as Portugal, Morocco, Tunisia, and Italy where this spirochete appears to infect vector ticks more frequently than other genospecies. Evolution of this zoonotic tick-borne microparasite is shaped by different environmental factors. Comprehensive phylogenetic analysis may give insight into how B. lusitaniae spreads to new geographic locations. Aim: We applied Bayesian statistical methods to B. lusitaniae multilocus sequence typing (MLST) data to study the migration routes of B. lusitaniae and its potential for further spread. Results: The discrete phylogeographic analysis placed origins of B. lusitaniae in Southeast Europe and identified at least two introductions of B. lusitaniae from Europe to North Africa. Estimated effective reproductive potential (Re), as a key indicator for a pathogen spread, suggested potential for further spread. Conclusion: The results of this study can provide beneficial information about the potential for further spread of B. lusitaniae in Europe and North Africa and estimation of necessity for the development of strategies to monitor and control Lyme borreliosis.", publisher = "Frontiers Media SA", journal = "Frontiers in Microbiology, Frontiers in Microbiology", title = "Evolutionary dynamics and geographical dispersal of Borrelia lusitaniae", pages = "1330914", volume = "15", doi = "10.3389/fmicb.2024.1330914" }
Ćirković, V., Veinović, G., Stanković, D., Mihaljica, D., Sukara, R.,& Tomanović, S.. (2024). Evolutionary dynamics and geographical dispersal of Borrelia lusitaniae. in Frontiers in Microbiology Frontiers Media SA., 15, 1330914. https://doi.org/10.3389/fmicb.2024.1330914
Ćirković V, Veinović G, Stanković D, Mihaljica D, Sukara R, Tomanović S. Evolutionary dynamics and geographical dispersal of Borrelia lusitaniae. in Frontiers in Microbiology. 2024;15:1330914. doi:10.3389/fmicb.2024.1330914 .
Ćirković, Valentina, Veinović, Gorana, Stanković, Daliborka, Mihaljica, Darko, Sukara, Ratko, Tomanović, Snežana, "Evolutionary dynamics and geographical dispersal of Borrelia lusitaniae" in Frontiers in Microbiology, 15 (2024):1330914, https://doi.org/10.3389/fmicb.2024.1330914 . .