Cross-sectional survey on Toxoplasma gondii infection in cattle, sheep and pigs in Serbia: Seroprevalence and risk factors
Samo za registrovane korisnike
2006
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Toxoplasmosis is a globally distributed zoonosis with a clinical impact in the unborn fetus and in the immunosuppressed individual. In Serbia, studies of risk factors for Toxoplasma gondii infection in humans have shown that the relatively high prevalence is associated mainly with consumption of undercooked meat and/or meat products. However, data on T gondii infection in domestic animals mostly used for human consumption are scarce. We thus conducted a cross-sectional survey on the seroprevalence of T gondii infection in a representative sample of cattle, sheep and pigs from different regions of Serbia between June 2002 and June 2003, and analyzed the main risk factors associated with the infection. Sera from 611 cattle (yearlings and adults of both sexes), 511 ewes, and 605 pigs (market-weight and sows), were examined for T gondii antibodies by the modified agglutination test. The seroprevalences determined were 76.3% in cattle, 84.5% in sheep and 28.9% in pigs. The antibody levels r...anged from 1:25 to 1:400 in cattle, and up to 1:25,600 in sheep and to 1: 12,800 in pigs. Among the seropositive, the proportion of high antibody levels ( ! 1: 1600), suggestive of acute infection, was 10% in sheep, and 4% in pigs. Possible association of the infection with biologically plausible risk factors including gender, age, herd size/farm type, type of housing, feeding practices and region, was analyzed by univariate analysis, and variables significant at P lt 0.1 were included in multivariate logistic regression models. The results showed that risk factors for cattle were small herd size (odds ratio, OR = 2.19, 95% confidence interval, CI = 1.28-3.75, P = 0.004) and farm location in Western Serbia (OR = 2.04, 95% CI = 1.10-3.79, P = 0.024), while housing in stables with access to outside pens was protective (OR = 0.37, 95% CI = 0.21-0.67, P = 0.001). In sheep, an increased risk of infection was found in ewes from state-owned flocks (OR = 4.18, 95% Cl = 2.18-8.00, P lt 0.001) vs. private flocks, and, interestingly, also in those from Western Serbia (OR = 4.66, 95% CI = 1.18-18.32, P = 0.028). In pigs, the risk of infection was highly increased in adult animals (OR = 3.87, 95% CI = 2.6-5.76, P lt 0.001), as well as in those from finishing type farms (OR = 3.96, 95% CI = 1.97-7.94, P lt 0.001). In addition to providing data on the current T gondii seroprevalence in meat animals in Serbia, the results of this study show the main risk factors associated with infection, thereby pointing to the type of preventive measures to reduce T gondii infection.
Ključne reči:
Toxoplasma gondii / cattle / sheep / pigs / seroprevalence / risk factors / SerbiaIzvor:
Veterinary Parasitology, 2006, 135, 2, 121-131Izdavač:
- Elsevier Science Bv, Amsterdam
DOI: 10.1016/j.vetpar.2005.08.010
ISSN: 0304-4017
PubMed: 16188388
WoS: 000234778600004
Scopus: 2-s2.0-29344466432
Institucija/grupa
Institut za medicinska istraživanjaTY - JOUR AU - Klun, Ivana AU - Đurković-Đaković, Olgica AU - Katić-Radivojević, Sofija AU - Nikolić, A. PY - 2006 UR - http://rimi.imi.bg.ac.rs/handle/123456789/133 AB - Toxoplasmosis is a globally distributed zoonosis with a clinical impact in the unborn fetus and in the immunosuppressed individual. In Serbia, studies of risk factors for Toxoplasma gondii infection in humans have shown that the relatively high prevalence is associated mainly with consumption of undercooked meat and/or meat products. However, data on T gondii infection in domestic animals mostly used for human consumption are scarce. We thus conducted a cross-sectional survey on the seroprevalence of T gondii infection in a representative sample of cattle, sheep and pigs from different regions of Serbia between June 2002 and June 2003, and analyzed the main risk factors associated with the infection. Sera from 611 cattle (yearlings and adults of both sexes), 511 ewes, and 605 pigs (market-weight and sows), were examined for T gondii antibodies by the modified agglutination test. The seroprevalences determined were 76.3% in cattle, 84.5% in sheep and 28.9% in pigs. The antibody levels ranged from 1:25 to 1:400 in cattle, and up to 1:25,600 in sheep and to 1: 12,800 in pigs. Among the seropositive, the proportion of high antibody levels ( ! 1: 1600), suggestive of acute infection, was 10% in sheep, and 4% in pigs. Possible association of the infection with biologically plausible risk factors including gender, age, herd size/farm type, type of housing, feeding practices and region, was analyzed by univariate analysis, and variables significant at P lt 0.1 were included in multivariate logistic regression models. The results showed that risk factors for cattle were small herd size (odds ratio, OR = 2.19, 95% confidence interval, CI = 1.28-3.75, P = 0.004) and farm location in Western Serbia (OR = 2.04, 95% CI = 1.10-3.79, P = 0.024), while housing in stables with access to outside pens was protective (OR = 0.37, 95% CI = 0.21-0.67, P = 0.001). In sheep, an increased risk of infection was found in ewes from state-owned flocks (OR = 4.18, 95% Cl = 2.18-8.00, P lt 0.001) vs. private flocks, and, interestingly, also in those from Western Serbia (OR = 4.66, 95% CI = 1.18-18.32, P = 0.028). In pigs, the risk of infection was highly increased in adult animals (OR = 3.87, 95% CI = 2.6-5.76, P lt 0.001), as well as in those from finishing type farms (OR = 3.96, 95% CI = 1.97-7.94, P lt 0.001). In addition to providing data on the current T gondii seroprevalence in meat animals in Serbia, the results of this study show the main risk factors associated with infection, thereby pointing to the type of preventive measures to reduce T gondii infection. PB - Elsevier Science Bv, Amsterdam T2 - Veterinary Parasitology T1 - Cross-sectional survey on Toxoplasma gondii infection in cattle, sheep and pigs in Serbia: Seroprevalence and risk factors EP - 131 IS - 2 SP - 121 VL - 135 DO - 10.1016/j.vetpar.2005.08.010 ER -
@article{ author = "Klun, Ivana and Đurković-Đaković, Olgica and Katić-Radivojević, Sofija and Nikolić, A.", year = "2006", abstract = "Toxoplasmosis is a globally distributed zoonosis with a clinical impact in the unborn fetus and in the immunosuppressed individual. In Serbia, studies of risk factors for Toxoplasma gondii infection in humans have shown that the relatively high prevalence is associated mainly with consumption of undercooked meat and/or meat products. However, data on T gondii infection in domestic animals mostly used for human consumption are scarce. We thus conducted a cross-sectional survey on the seroprevalence of T gondii infection in a representative sample of cattle, sheep and pigs from different regions of Serbia between June 2002 and June 2003, and analyzed the main risk factors associated with the infection. Sera from 611 cattle (yearlings and adults of both sexes), 511 ewes, and 605 pigs (market-weight and sows), were examined for T gondii antibodies by the modified agglutination test. The seroprevalences determined were 76.3% in cattle, 84.5% in sheep and 28.9% in pigs. The antibody levels ranged from 1:25 to 1:400 in cattle, and up to 1:25,600 in sheep and to 1: 12,800 in pigs. Among the seropositive, the proportion of high antibody levels ( ! 1: 1600), suggestive of acute infection, was 10% in sheep, and 4% in pigs. Possible association of the infection with biologically plausible risk factors including gender, age, herd size/farm type, type of housing, feeding practices and region, was analyzed by univariate analysis, and variables significant at P lt 0.1 were included in multivariate logistic regression models. The results showed that risk factors for cattle were small herd size (odds ratio, OR = 2.19, 95% confidence interval, CI = 1.28-3.75, P = 0.004) and farm location in Western Serbia (OR = 2.04, 95% CI = 1.10-3.79, P = 0.024), while housing in stables with access to outside pens was protective (OR = 0.37, 95% CI = 0.21-0.67, P = 0.001). In sheep, an increased risk of infection was found in ewes from state-owned flocks (OR = 4.18, 95% Cl = 2.18-8.00, P lt 0.001) vs. private flocks, and, interestingly, also in those from Western Serbia (OR = 4.66, 95% CI = 1.18-18.32, P = 0.028). In pigs, the risk of infection was highly increased in adult animals (OR = 3.87, 95% CI = 2.6-5.76, P lt 0.001), as well as in those from finishing type farms (OR = 3.96, 95% CI = 1.97-7.94, P lt 0.001). In addition to providing data on the current T gondii seroprevalence in meat animals in Serbia, the results of this study show the main risk factors associated with infection, thereby pointing to the type of preventive measures to reduce T gondii infection.", publisher = "Elsevier Science Bv, Amsterdam", journal = "Veterinary Parasitology", title = "Cross-sectional survey on Toxoplasma gondii infection in cattle, sheep and pigs in Serbia: Seroprevalence and risk factors", pages = "131-121", number = "2", volume = "135", doi = "10.1016/j.vetpar.2005.08.010" }
Klun, I., Đurković-Đaković, O., Katić-Radivojević, S.,& Nikolić, A.. (2006). Cross-sectional survey on Toxoplasma gondii infection in cattle, sheep and pigs in Serbia: Seroprevalence and risk factors. in Veterinary Parasitology Elsevier Science Bv, Amsterdam., 135(2), 121-131. https://doi.org/10.1016/j.vetpar.2005.08.010
Klun I, Đurković-Đaković O, Katić-Radivojević S, Nikolić A. Cross-sectional survey on Toxoplasma gondii infection in cattle, sheep and pigs in Serbia: Seroprevalence and risk factors. in Veterinary Parasitology. 2006;135(2):121-131. doi:10.1016/j.vetpar.2005.08.010 .
Klun, Ivana, Đurković-Đaković, Olgica, Katić-Radivojević, Sofija, Nikolić, A., "Cross-sectional survey on Toxoplasma gondii infection in cattle, sheep and pigs in Serbia: Seroprevalence and risk factors" in Veterinary Parasitology, 135, no. 2 (2006):121-131, https://doi.org/10.1016/j.vetpar.2005.08.010 . .