Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure

Ilić, Andjelija Ž.; De Luka, Silvio R.; Popović, Tamara B.; Debeljak-Martačić, Jasmina; Kojadinović, Milica; Ćirković, Saša; Ristić-Djurović, Jasna L.; Trbovich, Alexander M.

doi:10.1016/j.etap.2022.103853

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2022

Authors

Ilić, Andjelija Ž.

De Luka, Silvio R.

Popović, Tamara B.

Debeljak-Martačić, Jasmina

Kojadinović, Milica

Ćirković, Saša
Ristić-Djurović, Jasna L.
Trbovich, Alexander M.

Article (Published version)

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Abstract

We observed different outcomes upon the subacute exposure to the 128 mT highly homogeneous static magnetic field (SMF) when its orientation was (i) aligned with the vertical component of the geomagnetic field; (ii) in the opposite direction. We employed the fatty acids (FA) composition and digital image analyses (DIA) to provide insights into the underlying processes and examine the possible weak SMF effects. Swiss-Webster male mice were whole-body exposed for 1 h/day over five days. Brain tissue’s thin liquid chromatography resulted in brain FA composition, indicating a possible sequence of changes due to the SMF exposure. Quantitative DIA accurately assessed different image parameters. Delicate textural changes were revealed in the group where pathohistological or biochemical alterations have not been detected. DIA-based biological markers seem to be very promising for studying delicate tissue changes, which results from the high sensitivity and wide availability of DIA.

Keywords:

Brain fatty acids (FA) / Fractal (dimension/lacunarity) and multifractal analysis / Gray level co-occurrence matrix (GLCM) statistical features / Histograms of the local fractal dimension distributions / Thin liquid chromatography (TLC) and gas liquid chromatography (GC) / Vertical homogeneous static magnetic field (SMF) of different orientations

Source:
Environmental Toxicology and Pharmacology, 2022, 92, 103853-

Publisher:

Elsevier

Funding / projects:

DOI: 10.1016/j.etap.2022.103853

TY  - JOUR
AU  - Ilić, Andjelija Ž.
AU  - De Luka, Silvio R.
AU  - Popović, Tamara B.
AU  - Debeljak-Martačić, Jasmina
AU  - Kojadinović, Milica
AU  - Ćirković, Saša
AU  - Ristić-Djurović, Jasna L.
AU  - Trbovich, Alexander M.
PY  - 2022
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1229
AB  - We observed different outcomes upon the subacute exposure to the 128 mT highly homogeneous static magnetic field (SMF) when its orientation was (i) aligned with the vertical component of the geomagnetic field; (ii) in the opposite direction. We employed the fatty acids (FA) composition and digital image analyses (DIA) to provide insights into the underlying processes and examine the possible weak SMF effects. Swiss-Webster male mice were whole-body exposed for 1 h/day over five days. Brain tissue’s thin liquid chromatography resulted in brain FA composition, indicating a possible sequence of changes due to the SMF exposure. Quantitative DIA accurately assessed different image parameters. Delicate textural changes were revealed in the group where pathohistological or biochemical alterations have not been detected. DIA-based biological markers seem to be very promising for studying delicate tissue changes, which results from the high sensitivity and wide availability of DIA.
PB  - Elsevier
T2  - Environmental Toxicology and Pharmacology
T1  - Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure
SP  - 103853
VL  - 92
DO  - 10.1016/j.etap.2022.103853
ER  -

@article{
author = "Ilić, Andjelija Ž. and De Luka, Silvio R. and Popović, Tamara B. and Debeljak-Martačić, Jasmina and Kojadinović, Milica and Ćirković, Saša and Ristić-Djurović, Jasna L. and Trbovich, Alexander M.",
year = "2022",
abstract = "We observed different outcomes upon the subacute exposure to the 128 mT highly homogeneous static magnetic field (SMF) when its orientation was (i) aligned with the vertical component of the geomagnetic field; (ii) in the opposite direction. We employed the fatty acids (FA) composition and digital image analyses (DIA) to provide insights into the underlying processes and examine the possible weak SMF effects. Swiss-Webster male mice were whole-body exposed for 1 h/day over five days. Brain tissue’s thin liquid chromatography resulted in brain FA composition, indicating a possible sequence of changes due to the SMF exposure. Quantitative DIA accurately assessed different image parameters. Delicate textural changes were revealed in the group where pathohistological or biochemical alterations have not been detected. DIA-based biological markers seem to be very promising for studying delicate tissue changes, which results from the high sensitivity and wide availability of DIA.",
publisher = "Elsevier",
journal = "Environmental Toxicology and Pharmacology",
title = "Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure",
pages = "103853",
volume = "92",
doi = "10.1016/j.etap.2022.103853"
}

Ilić, A. Ž., De Luka, S. R., Popović, T. B., Debeljak-Martačić, J., Kojadinović, M., Ćirković, S., Ristić-Djurović, J. L.,& Trbovich, A. M.. (2022). Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure. in Environmental Toxicology and Pharmacology
Elsevier., 92, 103853.
https://doi.org/10.1016/j.etap.2022.103853

Ilić AŽ, De Luka SR, Popović TB, Debeljak-Martačić J, Kojadinović M, Ćirković S, Ristić-Djurović JL, Trbovich AM. Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure. in Environmental Toxicology and Pharmacology. 2022;92:103853.
doi:10.1016/j.etap.2022.103853 .

Ilić, Andjelija Ž., De Luka, Silvio R., Popović, Tamara B., Debeljak-Martačić, Jasmina, Kojadinović, Milica, Ćirković, Saša, Ristić-Djurović, Jasna L., Trbovich, Alexander M., "Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure" in Environmental Toxicology and Pharmacology, 92 (2022):103853,
https://doi.org/10.1016/j.etap.2022.103853 . .