Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure
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2022
Authors
Ilić, Andjelija Ž.
De Luka, Silvio R.

Popović, Tamara B.

Debeljak-Martačić, Jasmina

Kojadinović, Milica

Ćirković, Saša
Ristić-Djurović, Jasna L.
Trbovich, Alexander M.
Article (Published version)

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We observed different outcomes upon the subacute exposure to the 128 mT highly homogeneous static magnetic field (SMF) when its orientation was (i) aligned with the vertical component of the geomagnetic field; (ii) in the opposite direction. We employed the fatty acids (FA) composition and digital image analyses (DIA) to provide insights into the underlying processes and examine the possible weak SMF effects. Swiss-Webster male mice were whole-body exposed for 1 h/day over five days. Brain tissue’s thin liquid chromatography resulted in brain FA composition, indicating a possible sequence of changes due to the SMF exposure. Quantitative DIA accurately assessed different image parameters. Delicate textural changes were revealed in the group where pathohistological or biochemical alterations have not been detected. DIA-based biological markers seem to be very promising for studying delicate tissue changes, which results from the high sensitivity and wide availability of DIA.
Keywords:
Brain fatty acids (FA) / Fractal (dimension/lacunarity) and multifractal analysis / Gray level co-occurrence matrix (GLCM) statistical features / Histograms of the local fractal dimension distributions / Thin liquid chromatography (TLC) and gas liquid chromatography (GC) / Vertical homogeneous static magnetic field (SMF) of different orientationsSource:
Environmental Toxicology and Pharmacology, 2022, 92, 103853-Publisher:
- Elsevier
Funding / projects:
- Hypothalamic and medullary functional genomics in stress-induced hypertension (RS-41013)
- Control of infections by Apicomplexan pathogens: from novel drug targets to prediction (RS-41019)
- Biological effects, nutritional intake and status of folate and polysaturate fatty acid (PUFA): improvement of nutrition in Serbia (RS-41030)
- Optoelectronics nanodimension systems - the rout towards applications (RS-45003)
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200015 (University of Belgrade, Institute for Medical Research) (RS-200015)
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Institut za medicinska istraživanjaTY - JOUR AU - Ilić, Andjelija Ž. AU - De Luka, Silvio R. AU - Popović, Tamara B. AU - Debeljak-Martačić, Jasmina AU - Kojadinović, Milica AU - Ćirković, Saša AU - Ristić-Djurović, Jasna L. AU - Trbovich, Alexander M. PY - 2022 UR - http://rimi.imi.bg.ac.rs/handle/123456789/1229 AB - We observed different outcomes upon the subacute exposure to the 128 mT highly homogeneous static magnetic field (SMF) when its orientation was (i) aligned with the vertical component of the geomagnetic field; (ii) in the opposite direction. We employed the fatty acids (FA) composition and digital image analyses (DIA) to provide insights into the underlying processes and examine the possible weak SMF effects. Swiss-Webster male mice were whole-body exposed for 1 h/day over five days. Brain tissue’s thin liquid chromatography resulted in brain FA composition, indicating a possible sequence of changes due to the SMF exposure. Quantitative DIA accurately assessed different image parameters. Delicate textural changes were revealed in the group where pathohistological or biochemical alterations have not been detected. DIA-based biological markers seem to be very promising for studying delicate tissue changes, which results from the high sensitivity and wide availability of DIA. PB - Elsevier T2 - Environmental Toxicology and Pharmacology T1 - Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure SP - 103853 VL - 92 DO - 10.1016/j.etap.2022.103853 ER -
@article{ author = "Ilić, Andjelija Ž. and De Luka, Silvio R. and Popović, Tamara B. and Debeljak-Martačić, Jasmina and Kojadinović, Milica and Ćirković, Saša and Ristić-Djurović, Jasna L. and Trbovich, Alexander M.", year = "2022", abstract = "We observed different outcomes upon the subacute exposure to the 128 mT highly homogeneous static magnetic field (SMF) when its orientation was (i) aligned with the vertical component of the geomagnetic field; (ii) in the opposite direction. We employed the fatty acids (FA) composition and digital image analyses (DIA) to provide insights into the underlying processes and examine the possible weak SMF effects. Swiss-Webster male mice were whole-body exposed for 1 h/day over five days. Brain tissue’s thin liquid chromatography resulted in brain FA composition, indicating a possible sequence of changes due to the SMF exposure. Quantitative DIA accurately assessed different image parameters. Delicate textural changes were revealed in the group where pathohistological or biochemical alterations have not been detected. DIA-based biological markers seem to be very promising for studying delicate tissue changes, which results from the high sensitivity and wide availability of DIA.", publisher = "Elsevier", journal = "Environmental Toxicology and Pharmacology", title = "Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure", pages = "103853", volume = "92", doi = "10.1016/j.etap.2022.103853" }
Ilić, A. Ž., De Luka, S. R., Popović, T. B., Debeljak-Martačić, J., Kojadinović, M., Ćirković, S., Ristić-Djurović, J. L.,& Trbovich, A. M.. (2022). Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure. in Environmental Toxicology and Pharmacology Elsevier., 92, 103853. https://doi.org/10.1016/j.etap.2022.103853
Ilić AŽ, De Luka SR, Popović TB, Debeljak-Martačić J, Kojadinović M, Ćirković S, Ristić-Djurović JL, Trbovich AM. Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure. in Environmental Toxicology and Pharmacology. 2022;92:103853. doi:10.1016/j.etap.2022.103853 .
Ilić, Andjelija Ž., De Luka, Silvio R., Popović, Tamara B., Debeljak-Martačić, Jasmina, Kojadinović, Milica, Ćirković, Saša, Ristić-Djurović, Jasna L., Trbovich, Alexander M., "Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure" in Environmental Toxicology and Pharmacology, 92 (2022):103853, https://doi.org/10.1016/j.etap.2022.103853 . .