A group of European experts reappraised the guidelines on the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) previously published in 2014 [Lefaucheur et al., Clin Neurophysiol 2014;125:2150-206]. These updated recommendations take into account all rTMS publications, including data prior to 2014, as well as currently reviewed literature until the end of 2018. Level A evidence (definite efficacy) was reached for: high-frequency (HF) rTMS of the primary motor cortex (M1) contralateral to the painful side for neuropathic pain; HF-rTMS of the left dorsolateral prefrontal cortex (DLPFC) using a figure-of-8 or a Hl-coil for depression; low-frequency (LF) rTMS of contralesional M1 for hand motor recovery in the post-acute stage of stroke. Level B evidence (probable efficacy) was reached for: HF-rTMS of the left M1 or DLPFC for improving quality of life or pain, respectively, in fibromyalgia; HF-rTMS of bilateral M1 regions or the left DLPFC for improving motor impa...irment or depression, respectively, in Parkinson's disease; HF-rTMS of ipsilesional M1 for promoting motor recovery at the post-acute stage of stroke; intermittent theta burst stimulation targeted to the leg motor cortex for lower limb spasticity in multiple sclerosis; HF-rTMS of the right DLPFC in posttraumatic stress disorder; LF-rTMS of the right inferior frontal gyrus in chronic post-stroke non-fluent aphasia; LF-rTMS of the right DLPFC in depression; and bihemispheric stimulation of the DLPFC combining right-sided LF-rTMS (or continuous theta burst stimulation) and left-sided HF-rTMS (or intermittent theta burst stimulation) in depression. Level A/B evidence is not reached concerning efficacy of rTMS in any other condition. The current recommendations are based on the differences reached in therapeutic efficacy of real vs. sham rTMS protocols, replicated in a sufficient number of independent studies. This does not mean that the benefit produced by rTMS inevitably reaches a level of clinical relevance.
TY - JOUR
AU - Lefaucheur, Jean-Pascal
AU - Aleman, Andre
AU - Baeken, Chris
AU - Benninger, David H.
AU - Brunelin, Jerome
AU - Di Lazzaro, Vincenzo
AU - Filipović, Saša
AU - Grefkes, Christian
AU - Hasan, Alkomiet
AU - Hummel, Friedhelm C.
AU - Jaaskelainen, Satu K.
AU - Langguth, Berthold
AU - Leocani, Letizia
AU - Londero, Alain
AU - Nardone, Raffaele
AU - Nguyen, Jean-Paul
AU - Nyffeler, Thomas
AU - Oliveira-Maia, Albino J.
AU - Oliviero, Antonio
AU - Padberg, Frank
AU - Palm, Ulrich
AU - Paulus, Walter
AU - Poulet, Emmanuel
AU - Quartarone, Angelo
AU - Rachid, Fady
AU - Rektorova, Irena
AU - Rossi, Simone
AU - Sahlsten, Hanna
AU - Schecklmann, Martin
AU - Szekely, David
AU - Ziemann, Ulf
PY - 2020
UR - http://rimi.imi.bg.ac.rs/handle/123456789/1032
AB - A group of European experts reappraised the guidelines on the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) previously published in 2014 [Lefaucheur et al., Clin Neurophysiol 2014;125:2150-206]. These updated recommendations take into account all rTMS publications, including data prior to 2014, as well as currently reviewed literature until the end of 2018. Level A evidence (definite efficacy) was reached for: high-frequency (HF) rTMS of the primary motor cortex (M1) contralateral to the painful side for neuropathic pain; HF-rTMS of the left dorsolateral prefrontal cortex (DLPFC) using a figure-of-8 or a Hl-coil for depression; low-frequency (LF) rTMS of contralesional M1 for hand motor recovery in the post-acute stage of stroke. Level B evidence (probable efficacy) was reached for: HF-rTMS of the left M1 or DLPFC for improving quality of life or pain, respectively, in fibromyalgia; HF-rTMS of bilateral M1 regions or the left DLPFC for improving motor impairment or depression, respectively, in Parkinson's disease; HF-rTMS of ipsilesional M1 for promoting motor recovery at the post-acute stage of stroke; intermittent theta burst stimulation targeted to the leg motor cortex for lower limb spasticity in multiple sclerosis; HF-rTMS of the right DLPFC in posttraumatic stress disorder; LF-rTMS of the right inferior frontal gyrus in chronic post-stroke non-fluent aphasia; LF-rTMS of the right DLPFC in depression; and bihemispheric stimulation of the DLPFC combining right-sided LF-rTMS (or continuous theta burst stimulation) and left-sided HF-rTMS (or intermittent theta burst stimulation) in depression. Level A/B evidence is not reached concerning efficacy of rTMS in any other condition. The current recommendations are based on the differences reached in therapeutic efficacy of real vs. sham rTMS protocols, replicated in a sufficient number of independent studies. This does not mean that the benefit produced by rTMS inevitably reaches a level of clinical relevance.
PB - Elsevier Ireland Ltd, Clare
T2 - Clinical Neurophysiology
T1 - Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018)
EP - 528
IS - 2
SP - 474
VL - 131
DO - 10.1016/j.clinph.2019.11.002
UR - conv_4713
ER -
@article{
author = "Lefaucheur, Jean-Pascal and Aleman, Andre and Baeken, Chris and Benninger, David H. and Brunelin, Jerome and Di Lazzaro, Vincenzo and Filipović, Saša and Grefkes, Christian and Hasan, Alkomiet and Hummel, Friedhelm C. and Jaaskelainen, Satu K. and Langguth, Berthold and Leocani, Letizia and Londero, Alain and Nardone, Raffaele and Nguyen, Jean-Paul and Nyffeler, Thomas and Oliveira-Maia, Albino J. and Oliviero, Antonio and Padberg, Frank and Palm, Ulrich and Paulus, Walter and Poulet, Emmanuel and Quartarone, Angelo and Rachid, Fady and Rektorova, Irena and Rossi, Simone and Sahlsten, Hanna and Schecklmann, Martin and Szekely, David and Ziemann, Ulf",
year = "2020",
abstract = "A group of European experts reappraised the guidelines on the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) previously published in 2014 [Lefaucheur et al., Clin Neurophysiol 2014;125:2150-206]. These updated recommendations take into account all rTMS publications, including data prior to 2014, as well as currently reviewed literature until the end of 2018. Level A evidence (definite efficacy) was reached for: high-frequency (HF) rTMS of the primary motor cortex (M1) contralateral to the painful side for neuropathic pain; HF-rTMS of the left dorsolateral prefrontal cortex (DLPFC) using a figure-of-8 or a Hl-coil for depression; low-frequency (LF) rTMS of contralesional M1 for hand motor recovery in the post-acute stage of stroke. Level B evidence (probable efficacy) was reached for: HF-rTMS of the left M1 or DLPFC for improving quality of life or pain, respectively, in fibromyalgia; HF-rTMS of bilateral M1 regions or the left DLPFC for improving motor impairment or depression, respectively, in Parkinson's disease; HF-rTMS of ipsilesional M1 for promoting motor recovery at the post-acute stage of stroke; intermittent theta burst stimulation targeted to the leg motor cortex for lower limb spasticity in multiple sclerosis; HF-rTMS of the right DLPFC in posttraumatic stress disorder; LF-rTMS of the right inferior frontal gyrus in chronic post-stroke non-fluent aphasia; LF-rTMS of the right DLPFC in depression; and bihemispheric stimulation of the DLPFC combining right-sided LF-rTMS (or continuous theta burst stimulation) and left-sided HF-rTMS (or intermittent theta burst stimulation) in depression. Level A/B evidence is not reached concerning efficacy of rTMS in any other condition. The current recommendations are based on the differences reached in therapeutic efficacy of real vs. sham rTMS protocols, replicated in a sufficient number of independent studies. This does not mean that the benefit produced by rTMS inevitably reaches a level of clinical relevance.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Clinical Neurophysiology",
title = "Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018)",
pages = "528-474",
number = "2",
volume = "131",
doi = "10.1016/j.clinph.2019.11.002",
url = "conv_4713"
}
Lefaucheur, J., Aleman, A., Baeken, C., Benninger, D. H., Brunelin, J., Di Lazzaro, V., Filipović, S., Grefkes, C., Hasan, A., Hummel, F. C., Jaaskelainen, S. K., Langguth, B., Leocani, L., Londero, A., Nardone, R., Nguyen, J., Nyffeler, T., Oliveira-Maia, A. J., Oliviero, A., Padberg, F., Palm, U., Paulus, W., Poulet, E., Quartarone, A., Rachid, F., Rektorova, I., Rossi, S., Sahlsten, H., Schecklmann, M., Szekely, D.,& Ziemann, U.. (2020). Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018). in Clinical Neurophysiology
Elsevier Ireland Ltd, Clare., 131(2), 474-528.
https://doi.org/10.1016/j.clinph.2019.11.002
conv_4713
Lefaucheur J, Aleman A, Baeken C, Benninger DH, Brunelin J, Di Lazzaro V, Filipović S, Grefkes C, Hasan A, Hummel FC, Jaaskelainen SK, Langguth B, Leocani L, Londero A, Nardone R, Nguyen J, Nyffeler T, Oliveira-Maia AJ, Oliviero A, Padberg F, Palm U, Paulus W, Poulet E, Quartarone A, Rachid F, Rektorova I, Rossi S, Sahlsten H, Schecklmann M, Szekely D, Ziemann U. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018). in Clinical Neurophysiology. 2020;131(2):474-528.
doi:10.1016/j.clinph.2019.11.002
conv_4713 .
Lefaucheur, Jean-Pascal, Aleman, Andre, Baeken, Chris, Benninger, David H., Brunelin, Jerome, Di Lazzaro, Vincenzo, Filipović, Saša, Grefkes, Christian, Hasan, Alkomiet, Hummel, Friedhelm C., Jaaskelainen, Satu K., Langguth, Berthold, Leocani, Letizia, Londero, Alain, Nardone, Raffaele, Nguyen, Jean-Paul, Nyffeler, Thomas, Oliveira-Maia, Albino J., Oliviero, Antonio, Padberg, Frank, Palm, Ulrich, Paulus, Walter, Poulet, Emmanuel, Quartarone, Angelo, Rachid, Fady, Rektorova, Irena, Rossi, Simone, Sahlsten, Hanna, Schecklmann, Martin, Szekely, David, Ziemann, Ulf, "Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018)" in Clinical Neurophysiology, 131, no. 2 (2020):474-528,
https://doi.org/10.1016/j.clinph.2019.11.002 .,
conv_4713 .
