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Fructose-rich diet and walnut supplementation differently regulate rat hypothalamic and hippocampal glucose transporters expression
(Wiley, 2021)
BACKGROUND: Nutritional modulations may be considered a strategy to protect mental health. Neuronal homeostasis is highly dependent on the availability of glucose, which represents the primary energy source for the brain. ...
Mucoadhesive buccal tablets with propranolol hydrochloride: Formulation development and in vivo performances in experimental essential hypertension
(Elsevier, 2021)
The objective of this study was to formulate extended-release mucoadhesive buccal tablets of propranolol hydrochloride in order to provide a prolonged absorption of propranolol hydrochloride from the buccal mucosa and to ...
Characterization of personal solar ultraviolet radiation exposure using detrended fluctuation analysis
(Academic Press Inc Elsevier Science, San Diego, 2020)
Studies of personal solar ultraviolet radiation (pUVR) exposure are important to identify populations at-risk of excess and insufficient exposure given the negative and positive health impacts, respectively, of time spent ...
Selectivity of polyclonal repertoire of anti‐microbial IgA and its subclasses in saliva and serum in humans
(Wiley-Blackwell, 2022)
Increased interest in microbiota calls for the thorough analysis of antibody reactivity to different microorganisms. As salivary IgA represents the first line of defence against microorganisms contacting mucosal surfaces, ...
Oxidative stress status assessment of rats' brains injury following subacute exposure to K-oximes
(Elsevier, 2023)
Oxidative stress status and morphological injuries in the brain of Wistar rats induced by repeated application of selected acetylcholinesterase reactivators - asoxime, obidoxime, K027, K048, K074, and K075 were evaluated. ...
DNA, protein and lipid oxidative damage in tissues of spontaneously hypertensive versus normotensive rats
(Elsevier, 2021)
Oxidative damage to protein and lipid macromolecules in target organs in hypertension has been recognized as a major factor contributing to cardiovascular, cerebrovascular, and renal diseases. Data on protein and lipid ...
Exosomes and exosome-mimetics as targeted drug carriers: Where we stand and what the future holds?
(Elsevier, 2022)
Exosomes are a sub-group of extracellular vesicles, playing an important part in a cell-cell communication in many physiological and pathological conditions. Their size and competence for transferring material to recipient ...
Classification of time series of temperature variations from climatically homogeneous regions based on long-term persistence
(Wiley, Hoboken, 2021)
We used detrended methods for scaling analysis (DFA2 and DMA) and wavelet transform spectral analysis (WTS) to characterize long-term persistence (LTP) properties of temperature anomalies time series from observational ...
Integrated in vitro – in vivo – in silico studies in the pharmaceutical development of propranolol hydrochloride mucoadhesive buccal films
(Elsevier, 2023)
In order to exploit the advantage of drug delivery through the buccal mucosa, mucoadhesive buccal films with propranolol hydrochloride based on polyethylene oxide, hydroxypropyl methylcellulose, and polyvinyl alcohol have ...
BMP2 downregulates urokinase-type plasminogen activator via p38 MAPK: Implications in C2C12 cells myogenic differentiation
(Elsevier, 2021)
Bone morphogenetic protein (BMP)2 strongly affects the differentiation program of myoblast cells by inhibiting myogenesis and inducing osteogenic differentiation. In turn, extracellular matrix (ECM) proteinases, such as ...