Homogeneous static magnetic field of different orientation induces biological changes in subacutely exposed mice
Само за регистроване кориснике
2016
Аутори
Milovanovich, Ivan D.Ćirković, Saša
De Luka, Silvio R.
Đorđević, Drago M.
Ilić, Anđelija
Popović, Tamara B.
Arsić, Aleksandra
Obradović, Danilo D.
Oprić, Dejan
Ristić-Đurović, Jasna L.
Trbovich, Alexander M.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
It has been shown that static magnetic field (SMF) of moderate intensity produces considerable impact on biological systems. SMF can be homogeneous or inhomogeneous. In many studies, inhomogeneous SMF was employed. Aware that inhomogeneous SMF could result in experimental variability, we investigated the influence of a vertical homogeneous SMF of different orientation. Male Swiss-Webster 9- to 10-week-old mice were subacutely exposed to upward- and downward-oriented SMF of 128 mT generated by a cyclotron for 1 h/day during a 5-day period. We found that SMF affected various organs and that these effects were, to some degree, dependent on SMF orientation. Both upward- and downward-oriented SMF caused a reduction in the amount of total white blood cells (WBC) and lymphocytes in serum, a decrease of granulocytes in the spleen, kidney inflammation, and an increase in the amount of high-density lipoprotein (HDL). In addition, upward-oriented SMF caused brain edema and increased spleen cellul...arity. In contrast, downward-oriented SMF induced liver inflammation and a decrease in the amount of serum granulocytes. These effects might represent a specific redistribution of pro-inflammatory cells in blood and among various organs. It appears that homogeneous SMF of 128 mT affected specific organs in the body, rather than simultaneously and equally influencing the entire body system.
Кључне речи:
Homogeneous static magnetic field of different orientation / Liver / Brain / Kidney / Spleen / SerumИзвор:
Environmental Science & Pollution Research, 2016, 23, 2, 1584-1597Издавач:
- Springer Heidelberg, Heidelberg
Финансирање / пројекти:
- Функционална геномика хипоталамуса и медуле у хипертензији индукованој хроничним стресом (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41013)
- Контрола инфекција апикомплексним патогенима: од нових места деловања лека до предикције (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41019)
- Биолошки механизми, нутритивни унос и статус полинезасићених масних киселина и фолата: Унапређење исхране у Србији (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41030)
- Оптоелектронски нанодимензиони системи - пут ка примени (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45003)
- Физика и хемија са јонским сноповима (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45006)
DOI: 10.1007/s11356-015-5109-z
ISSN: 0944-1344
PubMed: 26377971
WoS: 000368200200062
Scopus: 2-s2.0-84954364366
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Milovanovich, Ivan D. AU - Ćirković, Saša AU - De Luka, Silvio R. AU - Đorđević, Drago M. AU - Ilić, Anđelija AU - Popović, Tamara B. AU - Arsić, Aleksandra AU - Obradović, Danilo D. AU - Oprić, Dejan AU - Ristić-Đurović, Jasna L. AU - Trbovich, Alexander M. PY - 2016 UR - http://rimi.imi.bg.ac.rs/handle/123456789/723 AB - It has been shown that static magnetic field (SMF) of moderate intensity produces considerable impact on biological systems. SMF can be homogeneous or inhomogeneous. In many studies, inhomogeneous SMF was employed. Aware that inhomogeneous SMF could result in experimental variability, we investigated the influence of a vertical homogeneous SMF of different orientation. Male Swiss-Webster 9- to 10-week-old mice were subacutely exposed to upward- and downward-oriented SMF of 128 mT generated by a cyclotron for 1 h/day during a 5-day period. We found that SMF affected various organs and that these effects were, to some degree, dependent on SMF orientation. Both upward- and downward-oriented SMF caused a reduction in the amount of total white blood cells (WBC) and lymphocytes in serum, a decrease of granulocytes in the spleen, kidney inflammation, and an increase in the amount of high-density lipoprotein (HDL). In addition, upward-oriented SMF caused brain edema and increased spleen cellularity. In contrast, downward-oriented SMF induced liver inflammation and a decrease in the amount of serum granulocytes. These effects might represent a specific redistribution of pro-inflammatory cells in blood and among various organs. It appears that homogeneous SMF of 128 mT affected specific organs in the body, rather than simultaneously and equally influencing the entire body system. PB - Springer Heidelberg, Heidelberg T2 - Environmental Science & Pollution Research T1 - Homogeneous static magnetic field of different orientation induces biological changes in subacutely exposed mice EP - 1597 IS - 2 SP - 1584 VL - 23 DO - 10.1007/s11356-015-5109-z ER -
@article{ author = "Milovanovich, Ivan D. and Ćirković, Saša and De Luka, Silvio R. and Đorđević, Drago M. and Ilić, Anđelija and Popović, Tamara B. and Arsić, Aleksandra and Obradović, Danilo D. and Oprić, Dejan and Ristić-Đurović, Jasna L. and Trbovich, Alexander M.", year = "2016", abstract = "It has been shown that static magnetic field (SMF) of moderate intensity produces considerable impact on biological systems. SMF can be homogeneous or inhomogeneous. In many studies, inhomogeneous SMF was employed. Aware that inhomogeneous SMF could result in experimental variability, we investigated the influence of a vertical homogeneous SMF of different orientation. Male Swiss-Webster 9- to 10-week-old mice were subacutely exposed to upward- and downward-oriented SMF of 128 mT generated by a cyclotron for 1 h/day during a 5-day period. We found that SMF affected various organs and that these effects were, to some degree, dependent on SMF orientation. Both upward- and downward-oriented SMF caused a reduction in the amount of total white blood cells (WBC) and lymphocytes in serum, a decrease of granulocytes in the spleen, kidney inflammation, and an increase in the amount of high-density lipoprotein (HDL). In addition, upward-oriented SMF caused brain edema and increased spleen cellularity. In contrast, downward-oriented SMF induced liver inflammation and a decrease in the amount of serum granulocytes. These effects might represent a specific redistribution of pro-inflammatory cells in blood and among various organs. It appears that homogeneous SMF of 128 mT affected specific organs in the body, rather than simultaneously and equally influencing the entire body system.", publisher = "Springer Heidelberg, Heidelberg", journal = "Environmental Science & Pollution Research", title = "Homogeneous static magnetic field of different orientation induces biological changes in subacutely exposed mice", pages = "1597-1584", number = "2", volume = "23", doi = "10.1007/s11356-015-5109-z" }
Milovanovich, I. D., Ćirković, S., De Luka, S. R., Đorđević, D. M., Ilić, A., Popović, T. B., Arsić, A., Obradović, D. D., Oprić, D., Ristić-Đurović, J. L.,& Trbovich, A. M.. (2016). Homogeneous static magnetic field of different orientation induces biological changes in subacutely exposed mice. in Environmental Science & Pollution Research Springer Heidelberg, Heidelberg., 23(2), 1584-1597. https://doi.org/10.1007/s11356-015-5109-z
Milovanovich ID, Ćirković S, De Luka SR, Đorđević DM, Ilić A, Popović TB, Arsić A, Obradović DD, Oprić D, Ristić-Đurović JL, Trbovich AM. Homogeneous static magnetic field of different orientation induces biological changes in subacutely exposed mice. in Environmental Science & Pollution Research. 2016;23(2):1584-1597. doi:10.1007/s11356-015-5109-z .
Milovanovich, Ivan D., Ćirković, Saša, De Luka, Silvio R., Đorđević, Drago M., Ilić, Anđelija, Popović, Tamara B., Arsić, Aleksandra, Obradović, Danilo D., Oprić, Dejan, Ristić-Đurović, Jasna L., Trbovich, Alexander M., "Homogeneous static magnetic field of different orientation induces biological changes in subacutely exposed mice" in Environmental Science & Pollution Research, 23, no. 2 (2016):1584-1597, https://doi.org/10.1007/s11356-015-5109-z . .