Antihyperlipidemic, antioxidant and weight-lowering effects of "Vitalplant"
2015
Аутори
Durendic-Brenesel, MajaPilija, Vladimir
Popović, Tamara B.
Arsić, Aleksandra
Milić, Miljan
Kojić, Danijela
Milić, Nataša
Misan, Aleksandra
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
BACKGROUND: "VITALPLANT" medicinal plant mixture, aimed at body weight regulation and metabolism enhancement was formulated in order to be incorporated as an ingredient in functional food formulations on the basis of known biological activity of the alder buckthorn bark, peppermint, caraway and parsley. METHODOLOGY: The body weight-lowering potential, hypolipidemic effects and antioxidant activity of "Vitalplant" mixture were examined on five groups of male Wistar rats on different food regimes for 14 weeks. RESULTS: "Vitalplant" mixture supplementation caused an increase in food intake, but induced a decrease in body weight gain. The lipid status and atherogenic index (AI) were significantly improved in "Vitalplant" mixture supplemented hyperlipidemic (HF) groups in comparison to HF group. "Vitalplant" mixture was able to influence the activity of antioxidant enzymes and to protect erythrocytes of the rats fed the HF diet from oxidative damage, which was indicated by significantly low...er malondialdehyde (MDA) levels in "Vitalplant"- HF groups in comparison to the HF group. CONCLUSION: "Vitalplant" mixture seemed to be beneficial for the reduction of body weight and improvement of antioxidant status of the erythrocytes, and its antihyperlipidemic property was highly active for enhancing the profile of plasma lipids in rats.
Кључне речи:
Antihyperlipidemic / Antioxidant / Peppermint / Caraway / Parsley / Alder buckthorn / Rats / In vivoИзвор:
Open Life Sciences, 2015, 10, 1, 291-298Издавач:
- De Gruyter Poland Sp Zoo, Warsaw
Финансирање / пројекти:
DOI: 10.1515/biol-2015-0030
ISSN: 2391-5412
WoS: 000371475600003
Scopus: 2-s2.0-84934299027
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Durendic-Brenesel, Maja AU - Pilija, Vladimir AU - Popović, Tamara B. AU - Arsić, Aleksandra AU - Milić, Miljan AU - Kojić, Danijela AU - Milić, Nataša AU - Misan, Aleksandra PY - 2015 UR - http://rimi.imi.bg.ac.rs/handle/123456789/646 AB - BACKGROUND: "VITALPLANT" medicinal plant mixture, aimed at body weight regulation and metabolism enhancement was formulated in order to be incorporated as an ingredient in functional food formulations on the basis of known biological activity of the alder buckthorn bark, peppermint, caraway and parsley. METHODOLOGY: The body weight-lowering potential, hypolipidemic effects and antioxidant activity of "Vitalplant" mixture were examined on five groups of male Wistar rats on different food regimes for 14 weeks. RESULTS: "Vitalplant" mixture supplementation caused an increase in food intake, but induced a decrease in body weight gain. The lipid status and atherogenic index (AI) were significantly improved in "Vitalplant" mixture supplemented hyperlipidemic (HF) groups in comparison to HF group. "Vitalplant" mixture was able to influence the activity of antioxidant enzymes and to protect erythrocytes of the rats fed the HF diet from oxidative damage, which was indicated by significantly lower malondialdehyde (MDA) levels in "Vitalplant"- HF groups in comparison to the HF group. CONCLUSION: "Vitalplant" mixture seemed to be beneficial for the reduction of body weight and improvement of antioxidant status of the erythrocytes, and its antihyperlipidemic property was highly active for enhancing the profile of plasma lipids in rats. PB - De Gruyter Poland Sp Zoo, Warsaw T2 - Open Life Sciences T1 - Antihyperlipidemic, antioxidant and weight-lowering effects of "Vitalplant" EP - 298 IS - 1 SP - 291 VL - 10 DO - 10.1515/biol-2015-0030 ER -
@article{ author = "Durendic-Brenesel, Maja and Pilija, Vladimir and Popović, Tamara B. and Arsić, Aleksandra and Milić, Miljan and Kojić, Danijela and Milić, Nataša and Misan, Aleksandra", year = "2015", abstract = "BACKGROUND: "VITALPLANT" medicinal plant mixture, aimed at body weight regulation and metabolism enhancement was formulated in order to be incorporated as an ingredient in functional food formulations on the basis of known biological activity of the alder buckthorn bark, peppermint, caraway and parsley. METHODOLOGY: The body weight-lowering potential, hypolipidemic effects and antioxidant activity of "Vitalplant" mixture were examined on five groups of male Wistar rats on different food regimes for 14 weeks. RESULTS: "Vitalplant" mixture supplementation caused an increase in food intake, but induced a decrease in body weight gain. The lipid status and atherogenic index (AI) were significantly improved in "Vitalplant" mixture supplemented hyperlipidemic (HF) groups in comparison to HF group. "Vitalplant" mixture was able to influence the activity of antioxidant enzymes and to protect erythrocytes of the rats fed the HF diet from oxidative damage, which was indicated by significantly lower malondialdehyde (MDA) levels in "Vitalplant"- HF groups in comparison to the HF group. CONCLUSION: "Vitalplant" mixture seemed to be beneficial for the reduction of body weight and improvement of antioxidant status of the erythrocytes, and its antihyperlipidemic property was highly active for enhancing the profile of plasma lipids in rats.", publisher = "De Gruyter Poland Sp Zoo, Warsaw", journal = "Open Life Sciences", title = "Antihyperlipidemic, antioxidant and weight-lowering effects of "Vitalplant"", pages = "298-291", number = "1", volume = "10", doi = "10.1515/biol-2015-0030" }
Durendic-Brenesel, M., Pilija, V., Popović, T. B., Arsić, A., Milić, M., Kojić, D., Milić, N.,& Misan, A.. (2015). Antihyperlipidemic, antioxidant and weight-lowering effects of "Vitalplant". in Open Life Sciences De Gruyter Poland Sp Zoo, Warsaw., 10(1), 291-298. https://doi.org/10.1515/biol-2015-0030
Durendic-Brenesel M, Pilija V, Popović TB, Arsić A, Milić M, Kojić D, Milić N, Misan A. Antihyperlipidemic, antioxidant and weight-lowering effects of "Vitalplant". in Open Life Sciences. 2015;10(1):291-298. doi:10.1515/biol-2015-0030 .
Durendic-Brenesel, Maja, Pilija, Vladimir, Popović, Tamara B., Arsić, Aleksandra, Milić, Miljan, Kojić, Danijela, Milić, Nataša, Misan, Aleksandra, "Antihyperlipidemic, antioxidant and weight-lowering effects of "Vitalplant"" in Open Life Sciences, 10, no. 1 (2015):291-298, https://doi.org/10.1515/biol-2015-0030 . .