Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats
2013
Аутори
Durendic-Brenesel, MajaPopović, Tamara B.
Pilija, Vladimir
Arsić, Aleksandra
Milić, Miljan
Kojić, Danijela
Jojić, Nikola
Milić, Nataša
Чланак у часопису (Објављена верзија)
Publisher's own license
Метаподаци
Приказ свих података о документуАпстракт
As a source of biologically active compounds, buckwheat has beneficial effects in nutrition due to its high content of flavonoids, particularly rutin. Aim of our study was to examine effects of buckwheat on plasma lipid status and phospholipids fatty acids composition, histological and parameters of oxidative stress in Wistar rats fed a high-fat diet. This study showed that buckwheat leaf and flower (BLF) mixture supplementation significantly reduce weight gain, plasma lipid concentrations and atherogenic index in rats fed a high-fat diet. Treatment of the high-fat group of animals with buckwheat significantly increased percentage of n-6 fatty acids as well as eicosapentaenoic acid (EPA) and decreased percentage of saturated fatty acids (SPA) and oleic acid. Buckwheat antioxidant effects diminished negative influence of high-fat diet in hyperlipidemic rats, while pathohistological analysis of liver confirmed changes after high-fat consumption. Our results showed hypolipidemic, antiathe...rogenic and antioxidative features of buckwheat leaf and flower mixture, and these parts of the plant with the highest rutin content could be beneficial in prevention and curing of hyperlipidemia.
Кључне речи:
buckwheat / plasma lipids / plasma phospholipids fatty acids / oxidative stress / hypolipidemic effectИзвор:
Bosnian Journal of Basic Medical Sciences, 2013, 13, 2, 100-108Издавач:
- Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, Cekalusa
Финансирање / пројекти:
- Функционални производи на бази жита намењени особама са метаболичким поремећајима (RS-MESTD-Technological Development (TD or TR)-31029)
DOI: 10.17305/bjbms.2013.2389
ISSN: 1512-8601
PubMed: 23725506
WoS: 000330925000007
Scopus: 2-s2.0-84883795107
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Durendic-Brenesel, Maja AU - Popović, Tamara B. AU - Pilija, Vladimir AU - Arsić, Aleksandra AU - Milić, Miljan AU - Kojić, Danijela AU - Jojić, Nikola AU - Milić, Nataša PY - 2013 UR - http://rimi.imi.bg.ac.rs/handle/123456789/500 AB - As a source of biologically active compounds, buckwheat has beneficial effects in nutrition due to its high content of flavonoids, particularly rutin. Aim of our study was to examine effects of buckwheat on plasma lipid status and phospholipids fatty acids composition, histological and parameters of oxidative stress in Wistar rats fed a high-fat diet. This study showed that buckwheat leaf and flower (BLF) mixture supplementation significantly reduce weight gain, plasma lipid concentrations and atherogenic index in rats fed a high-fat diet. Treatment of the high-fat group of animals with buckwheat significantly increased percentage of n-6 fatty acids as well as eicosapentaenoic acid (EPA) and decreased percentage of saturated fatty acids (SPA) and oleic acid. Buckwheat antioxidant effects diminished negative influence of high-fat diet in hyperlipidemic rats, while pathohistological analysis of liver confirmed changes after high-fat consumption. Our results showed hypolipidemic, antiatherogenic and antioxidative features of buckwheat leaf and flower mixture, and these parts of the plant with the highest rutin content could be beneficial in prevention and curing of hyperlipidemia. PB - Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, Cekalusa T2 - Bosnian Journal of Basic Medical Sciences T1 - Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats EP - 108 IS - 2 SP - 100 VL - 13 DO - 10.17305/bjbms.2013.2389 ER -
@article{ author = "Durendic-Brenesel, Maja and Popović, Tamara B. and Pilija, Vladimir and Arsić, Aleksandra and Milić, Miljan and Kojić, Danijela and Jojić, Nikola and Milić, Nataša", year = "2013", abstract = "As a source of biologically active compounds, buckwheat has beneficial effects in nutrition due to its high content of flavonoids, particularly rutin. Aim of our study was to examine effects of buckwheat on plasma lipid status and phospholipids fatty acids composition, histological and parameters of oxidative stress in Wistar rats fed a high-fat diet. This study showed that buckwheat leaf and flower (BLF) mixture supplementation significantly reduce weight gain, plasma lipid concentrations and atherogenic index in rats fed a high-fat diet. Treatment of the high-fat group of animals with buckwheat significantly increased percentage of n-6 fatty acids as well as eicosapentaenoic acid (EPA) and decreased percentage of saturated fatty acids (SPA) and oleic acid. Buckwheat antioxidant effects diminished negative influence of high-fat diet in hyperlipidemic rats, while pathohistological analysis of liver confirmed changes after high-fat consumption. Our results showed hypolipidemic, antiatherogenic and antioxidative features of buckwheat leaf and flower mixture, and these parts of the plant with the highest rutin content could be beneficial in prevention and curing of hyperlipidemia.", publisher = "Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, Cekalusa", journal = "Bosnian Journal of Basic Medical Sciences", title = "Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats", pages = "108-100", number = "2", volume = "13", doi = "10.17305/bjbms.2013.2389" }
Durendic-Brenesel, M., Popović, T. B., Pilija, V., Arsić, A., Milić, M., Kojić, D., Jojić, N.,& Milić, N.. (2013). Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats. in Bosnian Journal of Basic Medical Sciences Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, Cekalusa., 13(2), 100-108. https://doi.org/10.17305/bjbms.2013.2389
Durendic-Brenesel M, Popović TB, Pilija V, Arsić A, Milić M, Kojić D, Jojić N, Milić N. Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats. in Bosnian Journal of Basic Medical Sciences. 2013;13(2):100-108. doi:10.17305/bjbms.2013.2389 .
Durendic-Brenesel, Maja, Popović, Tamara B., Pilija, Vladimir, Arsić, Aleksandra, Milić, Miljan, Kojić, Danijela, Jojić, Nikola, Milić, Nataša, "Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats" in Bosnian Journal of Basic Medical Sciences, 13, no. 2 (2013):100-108, https://doi.org/10.17305/bjbms.2013.2389 . .