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Regulation of S100As Expression by Inflammatory Cytokines in Chronic Lymphocytic Leukemia
(MDPI, 2022)
The calcium-binding proteins S100A4, S100A8, and S100A9 are upregulated in chronic lymphocytic leukemia (CLL), while the S100A9 promotes NF-κB activity during disease progression. The S100-protein family has been involved ...
Gender Difference in SARS-CoV-2 Stimulation of Hyperinflammatory Response in Patients with COVID-19
(Belgrade: MEDAPP Association, 2022)
Background: Although women and men have the same prevalence, men with
COVID-19 are more at risk for worse outcomes and death, independent of age.
Methods: To observe the hyperinflammatory response regarding sex, we will ...
Systematic Bioinformatic Analyses of Nutrigenomic Modifications by Polyphenols Associated with Cardiometabolic Health in Humans—Evidence from Targeted Nutrigenomic Studies
(MDPI, 2021)
Cardiometabolic disorders are among the leading causes of mortality in the human population. Dietary polyphenols exert beneficial effects on cardiometabolic health in humans. Molecular mechanisms, however, are not completely ...
Effect of coordination mode of thiosemicarbazone on the biological activities of its Ru(II)-benzene complexes: Biomolecular interactions and anticancer activity via ROS-mediated mitochondrial apoptosis
(Elsevier, 2024)
Ru(II)-benzene complexes (P1 and P2) were synthesized using a thiosemicarbazone ligand (L1) in two different coordination modes, monodentate S and bidentate N,S, through carefully adjusted reaction conditions. Comprehensive ...
Circulatory Imbalance of Essential and Toxic Trace Elements in Pre-dialysis and Hemodialysis Patients
(Wiley-Blackwell, 2022)
The status of essential and toxic trace elements in patients with different stages of chronic kidney disease (CKD) is still unclear and not well characterized. The present study examined the circulatory levels of a wide ...
Effects of Transcranial Electrical Stimulation on Gambling and Gaming: A Systematic Review of Studies on Healthy Controls, Participants with Gambling/Gaming Disorder, and Substance Use Disorder
(Journal of Clinical Medicine, 2023)
Gambling disorder (GD) and internet gaming disorder (IGD) are formally recognized behavioral addictions with a rapidly growing prevalence and limited treatment options. Recently, transcranial electrical stimulation (tES) ...
Alteration of Lipid Metabolism in Prostate Cancer: Multifaceted Oncologic Implications
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Cancer is increasingly recognized as an extraordinarily heterogeneous disease featuring an intricate mutational landscape and vast intra- and intertumor variability on both genetic and phenotypic levels. Prostate cancer ...
Blinding in tDCS Studies: Correct End-of-Study Guess Does Not Moderate the Effects on Associative and Working Memory
(MDPI, 2022)
Transcranial direct current stimulation (tDCS) has become a valuable tool in cognitive neuroscience research as it enables causal inferences about neural underpinnings of cognition. However, studies using tDCS to modulate ...
Neurophysiological Predictors of Response to Medication in Parkinson's Disease
(Frontiers Media S.A., 2021)
Background: Although dopaminergic medication has been the foundation of Parkinson's disease (PD) therapy for decades, sensitive and specific therapeutic response biomarkers that allow for better treatment optimization are ...
Current opinions and practices in post-stroke movement disorders: Survey of movement disorders society members
(Elsevier, 2024)
Background: Post-stroke movement disorders (PSMD) encompass a wide array of presentations, which vary in mode of onset, phenomenology, response to treatment, and natural history. There are no evidence-based guidelines on ...