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Gait pattern in patients with different multiple sclerosis phenotypes
(Sage Publications Ltd, London, 2016)
Exosomes and exosome-mimetics as targeted drug carriers: Where we stand and what the future holds?
(Elsevier, 2022)
Exosomes are a sub-group of extracellular vesicles, playing an important part in a cell-cell communication in many physiological and pathological conditions. Their size and competence for transferring material to recipient ...
Jump training with different loads: effects on jumping performance and power output
(Springer, New York, 2013)
To investigate the selective effects of different types of external loads applied in vertical jump training on both the performance and muscle power output of the squat (SJ) and countermovement jump (CMJ). Physically active ...
Anti-metastatic and Anti-angiogenic Properties of Potential New Anti-cancer Drugs Based on Metal Complexes of Selenosemicarbazones
(Bentham Science Publ Ltd, Sharjah, 2012)
Our previous studies showed that zinc (II), cadmium (II) and nickel (II) complexes with 2-formylpyridine selenose-micarbazone induce apoptosis in cancer cells via activation of mitochondrial pathway. Herein, we reported ...
Effects of Nitric Oxide on Red Blood Cell Development and Phenotype
(Current Topics in Developmental Biology, 2008)
Nitric oxide (NO) is a diffusible free radical generated primarily by NO synthases (NOS), isoenzymes that convert the l-arginine and molecular oxygen to citrulline and NO in cells. Endothelial cells as well as macrophages, ...
Hydroxyurea induces the eNOS-cGMP pathway in endothelial cells
(Amer Soc Hematology, Washington, 2006)
Hydroxyurea is a cell-cycle-specific drug that has been used to treat myeloproliferative diseases and sickle cell anemia. We have recently shown that hydroxyurea, like nitric oxide (NO)-donor compounds, increased cGMP ...
Lower Serum Paraoxonase-1 Activity Is Related to Linoleic and Docosahexanoic Fatty Acids in Type 2 Diabetic Patients
(Elsevier Science Inc, New York, 2012)
Background. Serum paraoxonase-1(PON-1) activity is decreased in clinical conditions associated with low high-density lipoprotein cholesterol (HDL-C), increased lipid peroxidation and low-grade chronic inflammation, as in ...
Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity
(Academic Press Inc Elsevier Science, San Diego, 2007)
Recent reports have identified the proteasome as the primary degradation pathway for inducible, neuronal and endothelial nitric oxide synthase (NOS). We have demonstrated that hydroxyurea increased nitric oxide (NO) ...
ROS-NF kappa I' mediates TGF-beta 1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion
(Springer, Dordrecht, 2010)
TGF-beta 1 has been postulated as a pro-oncogenic factor in the late step of the tumoral progression. In transformed cells, TGF-beta 1 enhances the capacity to degrade the extracellular matrix, cell invasiveness and ...
Somesthesis
(Handbook of Physics in Medicine & Biology, 2010)
Somesthesis refers to the ability to detect external and internal stimuli, the nature of which could be mechanical, thermal, or even painful, the latter being sufficiently strong to damage tissues. This ability relies upon ...