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Role of Corticosteroids in Drug-Induced Liver Injury. A Systematic Review
(Frontiers Media S.A., 2022)
Introduction: Apart from cessation of the implicated agent leading to drug-induced liver injury (DILI), there is no standard therapy for DILI. Corticosteroids have been used in DILI, although their efficacy is unclear. ...
The Polymorphisms of Genes Encoding Catalytic Antioxidant Proteins Modulate the Susceptibility and Progression of Testicular Germ Cell Tumor
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
The simultaneous analysis of redox biomarkers and polymorphisms encoding for regulatory and catalytic antioxidant proteins was performed in order to evaluate their potential role in the development of testicular germ cell ...
Targeting Histone Deacetylases: Opportunities for Cancer Treatment and Chemoprevention
(Pharmaceutics, 2022)
The dysregulation of gene expression is a critical event involved in all steps of tumorigenesis. Aberrant histone and non-histone acetylation modifications of gene expression due to the abnormal activation of histone ...
Neutrophil Death in Myeloproliferative Neoplasms: Shedding More Light on Neutrophils as a Pathogenic Link to Chronic Inflammation
(MDPI, 2022)
Neutrophils are an essential component of the innate immune response, but their prolonged activation can lead to chronic inflammation. Consequently, neutrophil homeostasis is tightly regulated through balance between ...
Forest Fire Probability Mapping in Eastern Serbia: Logistic Regression versus Random Forest Method
(MDPI, 2021)
Forest fire risk has increased globally during the previous decades. The Mediterranean region is traditionally the most at risk in Europe, but continental countries like Serbia have experienced significant economic and ...
Systematic bioinformatic analysis of nutrigenomic data of flavanols in cell models of cardiometabolic disease
(Royal Soc Chemistry, Cambridge, 2020)
Flavanol intake positively influences several cardiometabolic risk factors in humans. However, the specific molecular mechanisms of action of flavanols, in terms of gene regulation, in the cell types relevant to cardiometabolic ...
Analysis of cell-biomaterial interaction through cellular bridge formation in the interface between hGMSCs and CaP bioceramics
(Nature Research, Berlin, 2020)
The combination of biomaterials and stem cells for clinical applications constitute a great challenge in bone tissue engineering. Hence, cellular networks derived from cells-biomaterials crosstalk have a profound influence ...
Specificity of 3D MSC Spheroids Microenvironment: Impact on MSC Behavior and Properties
(Springer, New York, 2020)
Mesenchymal stem cells (MSC) have been considered the promising candidates for the regenerative and personalized medicine due to their self-renewal potential, multilineage differentiation and immunomodulatory capacity. ...