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Bosentan and losartan ameliorate acute renal failure associated with mild but not strong NO blockade
(Oxford Univ Press, Oxford, 2007)
Background. Acute renal failure (ARF) is a devastating illness, especially when it occurs in various conditions with impaired nitric oxide (NO) synthesis, such as arterial hypertension, heart failure and some renal diseases. ...
Stimulated stromal cells induce gamma-globin gene expression in erythroid cells via nitric oxide production
(Elsevier Science Inc, New York, 2009)
Objective. We have previously shown that nitric oxide (NO) is involved in the hydroxyurea-induced increase of gamma-globin gene expression in cultured human erythroid progenitor cells and that hydroxyurea increases NO ...
Losartan Improved Antioxidant Defense, Renal Function and Structure of Postischemic Hypertensive Kidney
(Public Library Science, San Francisco, 2014)
Ischemic acute renal failure (ARF) is a highly complex disorder involving renal vasoconstriction, filtration failure, tubular obstruction, tubular backleak and generation of reactive oxygen species. Due to this complexity, ...
Neuronal Nitric Oxide Synthase Mediates the Effect of Ethanol on IgA
(Oxford Univ Press, Oxford, 2013)
Aims: We showed previously that the acute effect of ethanol on intestinal immunoglobulin A (IgA) expression might be mediated by endogenous nitric oxide (NO). To extend these findings, this study was designed to investigate ...
EURRECA's General Framework to make the process of setting up micronutrient recommendations explicit and transparent
(Cambridge Univ Press, Cambridge, 2010)
Physiological and public health basis for assessing micronutrient requirements in children and adolescents. The EURRECA network
(Wiley, Hoboken, 2010)
This paper provides an overview of the current knowledge relating to the nutritional requirements and corresponding recommended nutrient intake values of children and adolescents for micronutrients and specificities related ...
Sex and age differences and outcomes in acute coronary syndromes
(Elsevier Ireland Ltd, Clare, 2016)
Background: There is conflicting information about sex differences in presentation, treatment, and outcome after acute coronary syndromes (ACS) in the era of reperfusion therapy and percutaneous coronary intervention. The ...
Age-Related Differential Stimulation of Immune Response by Babesia microti and Borrelia burgdorferi During Acute Phase of Infection Affects Disease Severity
(Frontiers in Immunology, 2018)
Lyme disease is the most prominent tick-borne disease with 300,000 cases estimated by CDC every year while ~2,000 cases of babesiosis occur per year in the United States. Simultaneous infection with Babesia microti and ...
Protozoan parasite babesia microti subverts adaptive immunity and enhances lyme disease severity
(Frontiers in Microbiology, 2019)
Lyme disease is the most prominent tick-borne disease in the United States. Co-infections with the tick-transmitted pathogens Babesia microti and Borrelia burgdorferi sensu stricto are becoming a serious health problem. ...
Quantitative Proteome Heterogeneity in Myeloproliferative Neoplasm Subtypes and Association with JAK2 Mutation Status
(Amer Assoc Cancer Research, Philadelphia, 2017)
Apart from well-known genetic abnormalities, several studies have reported variations in protein expression in Philadelphianegative myeloproliferative neoplasm (MPN) patients that could contribute toward their clinical ...