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Prikaz rezultata 11-20 od 89
Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells
(Nature Publishing Group, London, 2017)
Chemotherapy in patients with inoperable or advanced breast cancer inevitably results in low-dose exposure of tumor-cell subset and senescence. Metabolically active senescent cells secrete multiple tumor promoting factors ...
Microarray and Proteomic Analyses of Myeloproliferative Neoplasms with a Highlight on the mTOR Signaling Pathway
(Public Library Science, San Francisco, 2015)
The gene and protein expression profiles in myeloproliferative neoplasms (MPNs) may reveal gene and protein markers of a potential clinical relevance in diagnosis, treatment and prediction of response to therapy. Using ...
Effects of anthocyanins and their gut metabolites on adenosine diphosphate-induced platelet activation and their aggregation with monocytes and neutrophils
(Elsevier Science Inc, New York, 2018)
Accumulating evidence suggests that anthocyanins play an important role in the cardioprotective effects associated with consumption of anthocyanin-rich foods. These benefits may partly be attributed to their effects on ...
Disturbances of platelets aggregation in patients with multiple myeloma
(Ferrata Storti Foundation, Pavia, 2010)
Approaches to mimic the complexity of the skeletal mesenchymal stem/stromal cell niche in vitro
(Ao Research Institute Davos-Ari, Davos, 2019)
Mesenchymal stem/stromal cells (MSCs) are an essential element of most modem tissue engineering and regenerative medicine approaches due to their multipotency and immunoregulatory functions. Despite the prospective value ...
Globin gene expression in correlation with G protein-related genes during erythroid differentiation
(Biomed Central Ltd, London, 2013)
Background: The guanine nucleotide binding protein (G protein)-coupled receptors (GPCRs) regulate cell growth, proliferation and differentiation. G proteins are also implicated in erythroid differentiation, and some of ...
Evidence for host genetic regulation of altered lipid metabolism in experimental toxoplasmosis supported with gene data mining results
(Public Library Science, San Francisco, 2017)
Toxoplasma gondii is one of the most successful parasites on Earth, infecting a wide array of mammals including one third of the global human population. The obligate intracellular protozoon is not capable of synthesizing ...
Relative roles of endothelin-1 and angiotensin II in experimental post-ischaemic acute renal failure
(Oxford Univ Press, Oxford, 2004)
Background. The relative roles of endothelin (ET)-1 and angiotensin (ANG) II in post-ischaemic acute renal failure (ARF) have not been fully established so far. With the aim of contributing to this goal, we assessed in ...
Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression
(Hindawi Ltd, London, 2015)
Transforming growth factor-beta (TGF-beta) and oxidative stress/ReactiveOxygen Species (ROS) both have pivotal roles in health and disease. In this review we are analyzing the interplay between TGF-beta and ROS in tumorigenesis ...
Angiogenic factors are increased in circulating granulocytes and CD34(+) cells of myeloproliferative neoplasms
(Wiley-Blackwell, Hoboken, 2017)
It has been shown that angiogenesis and inflammation play an important role in development of most hematological malignancies including the myeloproliferative neoplasm (MPN). The aim of this study was to investigate and ...