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Modulation of Functional Characteristics of Mesenchymal Stromal Cells by Acellular Preparation of Porcine Hemoglobin
(MDPI, 2022)
Exploring the potential usage of the acellular preparation of porcine hemoglobin (PHb) isolated from slaughterhouse blood as a cell culture media component, we have tested its effects on the functional characteristics of ...
Targeting Histone Deacetylases: Opportunities for Cancer Treatment and Chemoprevention
(Pharmaceutics, 2022)
The dysregulation of gene expression is a critical event involved in all steps of tumorigenesis. Aberrant histone and non-histone acetylation modifications of gene expression due to the abnormal activation of histone ...
Targeting Stress Erythropoiesis Pathways in Cancer
(Frontiers Media S.A, 2022)
Cancer-related anemia (CRA) is a common multifactorial disorder that adversely affects the quality of life and overall prognosis in patients with cancer. Safety concerns associated with the most common CRA treatment options, ...
Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure
(Elsevier, 2022)
We observed different outcomes upon the subacute exposure to the 128 mT highly homogeneous static magnetic field (SMF) when its orientation was (i) aligned with the vertical component of the geomagnetic field; (ii) in the ...
The Polymorphisms of Genes Encoding Catalytic Antioxidant Proteins Modulate the Susceptibility and Progression of Testicular Germ Cell Tumor
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
The simultaneous analysis of redox biomarkers and polymorphisms encoding for regulatory and catalytic antioxidant proteins was performed in order to evaluate their potential role in the development of testicular germ cell ...
Application of Perinatal Derivatives on Oncological Preclinical Models: A Review of Animal Studies
(International Journal of Molecular Sciences, 2022)
The increasing cancer incidence has certified oncological management as one of the most critical challenges for the coming decades. New anticancer strategies are still needed, despite the significant advances brought to ...
Interleukin-17 modulates uPA and MMP2 expression in human periodontal ligament mesenchymal stem cells: Involvement of the ERK1/2 MAPK pathway
(Srpsko biološko društvo, 2022)
Periodontal disease is a chronic infection of periodontal tissue characterized by extracellular matrix (ECM) degradation due to increased expression of plasminogen activators and matrix metalloproteinases (MMPs) and various ...
Grapefruit Juice Flavanones Modulate the Expression of Genes Regulating Inflammation, Cell Interactions and Vascular Function in Peripheral Blood Mononuclear Cells of Postmenopausal Women
(Frontiers Media S.A., 2022)
Grapefruit is a rich source of flavanones, phytochemicals suggested excreting
vasculoprotective effects. We previously showed that flavanones in grapefruit juice
(GFJ) reduced postmenopausal women’s pulse-wave velocity ...
Inhibition of proinflammatory signaling impairs fibrosis of bone marrow mesenchymal stromal cells in myeloproliferative neoplasms
(Korean Society of Medical Biochemistry and Molecular Biology [Associate Organisation]Springer Nature [Commercial Publisher], 2022)
Although bone marrow-derived mesenchymal stromal cells (BM-MSCs) have been identified as a major cellular source of fibrosis, the exact molecular mechanism and signaling pathways involved have not been identified thus far. ...
Optimization of the extraction of antioxidants from stinging nettle leaf using response surface methodology
(Society of Chemists and Technologists of Macedonia and Ss. Cyril and Methodius University in Skopje, 2022)
The aim of this study was to optimize the parameters for the extraction of total flavonoids from stinging nettle leaf. Comparison of the effects of different solvents on total flavonoid content showed that, ...