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Experimental and systems biology studies of the molecular basis for the radioresistance of prostate carcinoma cells
(Springer, New York, 2008)
Molecular mechanisms for the gamma-ionizing radiation (IR) resistance of human prostate cancer cells, PC-3, are not quite clear. Since the low-LET-IR effects are primarily manifested by the generation of reactive oxygen ...
Serum beta(2)-microglobulin as a marker of congenital toxoplasmosis and cytomegalovirus infection in preterm neonates
(Karger, Basel, 2008)
Background: Fetal serum beta(2)-microglobulin (beta M-2) has been reported as a reliable indicator of fetal infectious diseases. Objectives: To evaluate serum beta M-2 as a marker of congenital toxoplasmosis or cytomegalovirus ...
Dietary lipid intake influences the level of cholesterol bound to haemoglobin in human erythrocytes
(Springer Heidelberg, Heidelberg, 2008)
Background Blood cholesterol levels are affected by diet and in particular by the type of fat intake. We originally showed that a significant but variable amount of cholesterol is firmly bound to haemoglobin (Hb) yielding ...
Glycosylation of IgG B cell receptor (IgG BCR) in multiple myeloma: relationship between sialylation and the signal activity of IgG BCR
(Springer, Dordrecht, 2008)
Little is known about the glycosylation of the isotype switched B cell receptor (BCR) in multiple myeloma, and the way it might affect receptor function. In this work IgG BCRs isolated from the individual lysates of ...
Assessment of the risk of contracting Lyme disease in areas with significant human presence
(Arquivo Brasileiro Medicina Veterinaria Zootecnia, Minas Gerais, 2008)
in order to describe seasonal changes in Lyme disease risk rate at three localities in Serbia, a total of 1,542 Ixodes ricinus ticks (493 nymphs; 525 females, and 524 males) were examined from 2003 to 2004. The prevalence ...
The combination of gamma ionizing radiation and 8-Cl-cAMP induces synergistic cell growth inhibition and induction of apoptosis in human prostate cancer cells
(Springer, Dordrecht, 2008)
The antiproliferative and cytotoxic potential of the nucleotide analog 8-Cl-cAMP was tested in PC-3 and DU145 metastatic human prostate cancer cells. The drug was examined as the only therapeutic agent and in combination ...
Alport's syndrome and benign familial haematuria: light and electron microscopic studies of the kidney
(Srpsko lekarsko društvo, Beograd, 2008)
INTRODUCTION Hereditary nephropathy is clinically characterized by the familial occurrence in successive generations of progressive haematuric nephritis and neural hearing loss. Hereditary nephropathy of Alport's syndrome ...
The prevalence and risk of hepatitis flares in a Serbian cohort of HIV and HCV co-infected patients treated with HAART
(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2008)
Despite substantial benefits of HAART treatment of HIV-infected patients, cumulative long-term toxicity, including drug-induced hepatotoxicity, has emerged as an important complication. Thus, to examine the prevalence and ...
Effects of long-term losartan and L-arginine treatment on haemodynamics, glomerular filtration, and SOD activity in spontaneously hypertensive rats
(Canadian Science Publishing, Ottawa, 2008)
Recently, it has been reported that losartan, an angiotensin II receptor (ATR) antagonist, depresses the angiotensin II-induced production of superoxide radicals. Also, in spontaneously hypertensive rats (SHR) endothelial ...
Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells
(Amer Soc Hematology, Washington, 2008)
Hydroxyurea, a drug widely used for treating myeloproliferative diseases, has also been approved for the treatment of sickle cell disease by raising fetal hemoglobin (HbF). We have shown that nitric oxide (NO) and the ...