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Telmisartan induces melanoma cell apoptosis and synergizes with vemurafenib in vitro by altering cell bioenergetics
(Chinese Anti-Cancer Assoc, Tianjin, 2019)
Objective: Despite recent advancements in targeted therapy and immunotherapies, prognosis for metastatic melanoma patients remains extremely poor. Development of resistance to previously effective treatments presents a ...
Binding of enterolactone and enterodiol to human serum albumin: increase of cysteine-34 thiol group reactivity
(Royal Soc Chemistry, Cambridge, 2016)
The interaction of polyphenolic molecules with human serum albumin (HSA) could lead to changes in the reactivity of the HSA Cys34 thiol group (HSA-SH). The influences of enterolactone (EL) and enterodiol (ED) binding on ...
Tempol supplementation does not overcome beneficial effect of losartan in hypertensive rats with early course of focal segmental glomerulosclerosis
(Lippincott Williams & Wilkins, Philadelphia, 2016)
Aronia (Aronia melanocarpa) phenolics bioavailability in a combined in vitro digestion/Caco-2 cell model is structure and colon region dependent
(Elsevier Science Bv, Amsterdam, 2017)
Aronia phenolics are considered to be beneficial for cardiovascular health, but are not always bioavailable. In this study, we evaluated the in vitro bioavailability of Aronia juice phenolics by combination of intestinal ...
Correlation between ER, PR, HER-2, Bcl-2, p53, proliferative and apoptotic indexes with HER-2 gene amplification and TOP2A gene amplification and deletion in four molecular subtypes of breast cancer
(Springer, Dordrecht, 2014)
The aim of our study was to investigate HER-2 and TOP2A gene status and their correlation with Bcl-2, p53, Ki67, ssDNA, and clinicopathological parameters in four molecular subtypes of breast cancer. Seventy-four ...
Serum interleukin-17 & nitric oxide levels in patients with primary Sjogren's syndrome
(Medknow Publications & Media Pvt Ltd, Mumbai, 2012)
Background & objectives: The interleukin (IL)-17 producing T-helper cells have been linked to pathogenesis of autoimmunity and mostly investigated in rheumatoid arthritis (RA). In this study we tested the IL-17 levels, as ...
Moderate consumption of alcohol-free red wine provide more beneficial effects on systemic haemodynamics, lipid profile and oxidative stress in spontaneously hypertensive rats than red wine
(Elsevier Science Bv, Amsterdam, 2016)
Numerous studies have shown that moderate wine consumption is associated with decreased incidence of cardiovascular disease, including hypertension. Others observed that moderate alcohol consumption lowers the risk of ...
Micronutrient intake and status in Central and Eastern Europe compared with other European countries, results from the EURRECA network
(Cambridge Univ Press, Cambridge, 2013)
Objective: To compare micronutrient intakes and status in Central and Eastern Europe (CEE) with those in other European countries and with reference values. Design: Review of the micronutrient intake/status data from open ...
Consumption of pomegranate juice decreases blood lipid peroxidation and levels of arachidonic acid in women with metabolic syndrome
(Wiley, Hoboken, 2017)
BACKGROUNDPomegranate juice is a rich source of polyphenols and is thus a promising dietary antioxidant with numerous health-promoting effects. These include a beneficial impact on cardiovascular health that could be partly ...
Improving the reporting quality of intervention trials addressing the inter-individual variability in response to the consumption of plant bioactives: quality index and recommendations
(Springer Heidelberg, Heidelberg, 2019)
Key messages The reporting quality of human studies on inter-individual variation in response to plant bioactives is generally low and should be significantly improved. There is no specific guidance for reporting studies ...