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Interleukin-6 (IL-6) and low O-2 concentration (1%) synergize to improve the maintenance of hematopoietic stem cells (Pre-CFC)
(Wiley, Hoboken, 2007)
Low O-2 concentration (1%) favors the self-renewal of hematopoietic stem cells and inhibits committed progenitors (CFC). Since IL-6 influences both stem cells and committed progenitors at 20% O-2, we studied its effects ...
Controlled-rate versus uncontrolled-rate freezing as predictors for platelet cryopreservation efficacy
(Wiley, Hoboken, 2006)
BACKGROUND: Cryobiologic variables responsible for cell injuries and freezing techniques applicable in medical cryopractice should be revised and/or reengineered for minimizing cryoinjuries and maximizing cell recovery. ...
Signaling pathways implicated in hematopoietic progenitor cell proliferation and differentiation
(Sage Publications Ltd, London, 2007)
The objective of this study was to investigate the signal transduction pathways associated with the clonal development of myeloid and erythroid progenitor cells. The contribution of particular signaling molecules of protein ...
Cross-sectional survey on Toxoplasma gondii infection in cattle, sheep and pigs in Serbia: Seroprevalence and risk factors
(Elsevier Science Bv, Amsterdam, 2006)
Toxoplasmosis is a globally distributed zoonosis with a clinical impact in the unborn fetus and in the immunosuppressed individual. In Serbia, studies of risk factors for Toxoplasma gondii infection in humans have shown ...
The efficacy of two protocols for inducing motor cortex plasticity in healthy humans - TMS study
(General Physiol And Biophysics, Bratislava, 2009)
Stimulation-induced plasticity represents an experimental model of motor cortex reorganization. It can be produced in awaked humans by combining the non-invasive electrical stimulation of somatosensory afferents via mixed ...
A human origin type II strain of Toxoplasma gondii causing severe encephalitis in mice
(Elsevier Science Bv, Amsterdam, 2006)
Despite its capacity for sexual reproduction and global distribution, Toxoplasma gondii has a highly clonal structure, with the majority of isolates belonging to three distinct clonal types. Congenital toxoplasmosis has ...
Hematopoietic changes and altered reactivity to IL-17 in Syphacia obvelata-infected mice
(Elsevier Ireland Ltd, Clare, 2006)
Pinworm parasites commonly infect laboratory mice with high prevalence even in well-managed animal colonies. Although often considered as irrelevant, these parasites if undetected may significantly interfere with the ...
Regional hemodynamics after chronic nitric oxide inhibition in spontaneously hypertensive rats
(Elsevier Science Inc, New York, 2000)
Background: Inhibition of nitric oxide (NO) synthase by L-arginine analogs is associated with elevation of blood pressure in rats. Because endothelium-dependent vasomotion in different vascular beds is not homogenous, the ...
Glycosylation of IgG B cell receptor (IgG BCR) in multiple myeloma: relationship between sialylation and the signal activity of IgG BCR
(Springer, Dordrecht, 2008)
Little is known about the glycosylation of the isotype switched B cell receptor (BCR) in multiple myeloma, and the way it might affect receptor function. In this work IgG BCRs isolated from the individual lysates of ...
Evidence for an association of high levels of endogenous Acetyl-Ser-Asp-Lys-Pro, a potent mediator of angiogenesis, with acute myeloid leukemia development
(Taylor & Francis Ltd, Abingdon, 2006)
Evidence from clinical and laboratory studies suggests that angiogenesis is important in the progression of solid tumours and hematologic malignancies. We have shown that the naturally occurring tetrapeptide Acetyl-Ser-Asp-Lys-Pro ...