A substituent-modified new salicylaldehyde-diphenyl-azine based AIEgen: A promising skeleton for copper ion sensor
Samo za registrovane korisnike
2024
Autori
Jain, AbhinavDe, Soumik
Mukherjee, Debanggana
Haribabu, Jebiti
Santibanez, Juan F.
Barman, Pranjit
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
In this study, we have reported a novel 4-bromo-salicylaldehyde-diphenyl-azine (B-1), a new member of salicylaldehyde-diphenyl-azine (SDPA) family known for its excellent sensing properties. In contrast to the previously reported AIEgens, we found that the bromo-substitution at the 4th position of the salicylaldehyde moiety blue-shifted the emission by 10 and 15 nm as compared to the unsubstituted (Tong et.al 2017) and Bromo at the 5th position (Jain et.al 2023) respectively. Moreover, B-1 crystallizes instantly as the cooling process starts, which was not observed in the previously reported scaffolds. The sensing investigation again demonstrated the precise and ultrasensitive behavior of B-1 for copper ions. B-1 has a very low LOD value i.e. 29.2 x 10-8 M with a high association constant and binds with copper ion in 2:1 mode. This time we also analyzed the practical applicability in the solid phase using cotton swabs and performed the real-time estimation of copper ions in water and b...iological samples like urine and blood serum. The excellent percentage recovery and the RSD value suggest the precision of the experiments. Further, we also perform the sensing in living cancer HeLa cells. Altogether, we found that the SDPA skeleton is precise and ultrasensitive for copper ions and versatile which can be used variously to detect copper ions in the real world. This research will surely help in developing new specific skeleton-based AIEgens with desirable emission properties and precise applications in the future.
Ključne reči:
AIE-ESIPT, versatile skeleton / Copper ion sensing / Test-kit application / Real-time estimation / BioimagingIzvor:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 322, 124824-Izdavač:
- Elsevier
DOI: 10.1016/j.saa.2024.124824
ISSN: 1386-1425
WoS: 001274656800001
Scopus: 2-s2.0-85198742348
Institucija/grupa
Institut za medicinska istraživanjaTY - JOUR AU - Jain, Abhinav AU - De, Soumik AU - Mukherjee, Debanggana AU - Haribabu, Jebiti AU - Santibanez, Juan F. AU - Barman, Pranjit PY - 2024 UR - http://rimi.imi.bg.ac.rs/handle/123456789/1508 AB - In this study, we have reported a novel 4-bromo-salicylaldehyde-diphenyl-azine (B-1), a new member of salicylaldehyde-diphenyl-azine (SDPA) family known for its excellent sensing properties. In contrast to the previously reported AIEgens, we found that the bromo-substitution at the 4th position of the salicylaldehyde moiety blue-shifted the emission by 10 and 15 nm as compared to the unsubstituted (Tong et.al 2017) and Bromo at the 5th position (Jain et.al 2023) respectively. Moreover, B-1 crystallizes instantly as the cooling process starts, which was not observed in the previously reported scaffolds. The sensing investigation again demonstrated the precise and ultrasensitive behavior of B-1 for copper ions. B-1 has a very low LOD value i.e. 29.2 x 10-8 M with a high association constant and binds with copper ion in 2:1 mode. This time we also analyzed the practical applicability in the solid phase using cotton swabs and performed the real-time estimation of copper ions in water and biological samples like urine and blood serum. The excellent percentage recovery and the RSD value suggest the precision of the experiments. Further, we also perform the sensing in living cancer HeLa cells. Altogether, we found that the SDPA skeleton is precise and ultrasensitive for copper ions and versatile which can be used variously to detect copper ions in the real world. This research will surely help in developing new specific skeleton-based AIEgens with desirable emission properties and precise applications in the future. PB - Elsevier T2 - Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy T1 - A substituent-modified new salicylaldehyde-diphenyl-azine based AIEgen: A promising skeleton for copper ion sensor SP - 124824 VL - 322 DO - 10.1016/j.saa.2024.124824 ER -
@article{ author = "Jain, Abhinav and De, Soumik and Mukherjee, Debanggana and Haribabu, Jebiti and Santibanez, Juan F. and Barman, Pranjit", year = "2024", abstract = "In this study, we have reported a novel 4-bromo-salicylaldehyde-diphenyl-azine (B-1), a new member of salicylaldehyde-diphenyl-azine (SDPA) family known for its excellent sensing properties. In contrast to the previously reported AIEgens, we found that the bromo-substitution at the 4th position of the salicylaldehyde moiety blue-shifted the emission by 10 and 15 nm as compared to the unsubstituted (Tong et.al 2017) and Bromo at the 5th position (Jain et.al 2023) respectively. Moreover, B-1 crystallizes instantly as the cooling process starts, which was not observed in the previously reported scaffolds. The sensing investigation again demonstrated the precise and ultrasensitive behavior of B-1 for copper ions. B-1 has a very low LOD value i.e. 29.2 x 10-8 M with a high association constant and binds with copper ion in 2:1 mode. This time we also analyzed the practical applicability in the solid phase using cotton swabs and performed the real-time estimation of copper ions in water and biological samples like urine and blood serum. The excellent percentage recovery and the RSD value suggest the precision of the experiments. Further, we also perform the sensing in living cancer HeLa cells. Altogether, we found that the SDPA skeleton is precise and ultrasensitive for copper ions and versatile which can be used variously to detect copper ions in the real world. This research will surely help in developing new specific skeleton-based AIEgens with desirable emission properties and precise applications in the future.", publisher = "Elsevier", journal = "Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy", title = "A substituent-modified new salicylaldehyde-diphenyl-azine based AIEgen: A promising skeleton for copper ion sensor", pages = "124824", volume = "322", doi = "10.1016/j.saa.2024.124824" }
Jain, A., De, S., Mukherjee, D., Haribabu, J., Santibanez, J. F.,& Barman, P.. (2024). A substituent-modified new salicylaldehyde-diphenyl-azine based AIEgen: A promising skeleton for copper ion sensor. in Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Elsevier., 322, 124824. https://doi.org/10.1016/j.saa.2024.124824
Jain A, De S, Mukherjee D, Haribabu J, Santibanez JF, Barman P. A substituent-modified new salicylaldehyde-diphenyl-azine based AIEgen: A promising skeleton for copper ion sensor. in Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2024;322:124824. doi:10.1016/j.saa.2024.124824 .
Jain, Abhinav, De, Soumik, Mukherjee, Debanggana, Haribabu, Jebiti, Santibanez, Juan F., Barman, Pranjit, "A substituent-modified new salicylaldehyde-diphenyl-azine based AIEgen: A promising skeleton for copper ion sensor" in Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 322 (2024):124824, https://doi.org/10.1016/j.saa.2024.124824 . .