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Relationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells

dc.creatorRamirez-Tagle, Rodrigo
dc.creatorAlvarado-Soto, Leonor
dc.creatorSantibanez, Juan F.
dc.creatorEcheverria, Cesar
dc.date.accessioned2023-11-19T09:08:07Z
dc.date.available2023-11-19T09:08:07Z
dc.date.issued2023
dc.identifier.issn2339-9686
dc.identifier.urihttp://rimi.imi.bg.ac.rs/handle/123456789/1361
dc.description.abstractRelationships between the structural characteristic of curcumin and dimethoxycurcumin and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with the curcumin and dimethoxycurcumin resulted in apoptosis induction and dose-dependent inhibition of cell proliferation. The calculated docking and the DFT method, suggest a structure-activity relationship between the activities of dimethoxycurcumin and curcumin structure and the apoptosis in HepG2 cells
dc.languageen
dc.publisherAsociacion de Quimicos del Instituto Quimico de Sarria
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceAfinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry
dc.sourceAfinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry
dc.subjectcurcumins
dc.subjecthepatocarcinoma
dc.titleRelationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells
dc.typearticleen
dc.rights.licenseBY-NC-ND
dc.citation.epage179
dc.citation.issue599
dc.citation.spage175
dc.citation.volume80
dc.identifier.doi10.55815/417980
dc.identifier.fulltexthttp://rimi.imi.bg.ac.rs/bitstream/id/3142/Relationships_between_the_structural_characteristic_of_curcumins_pub_2023.pdf
dc.type.versionpublishedVersion


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