Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure
Само за регистроване кориснике
2022
Аутори
Ilić, Andjelija Ž.De Luka, Silvio R.
Popović, Tamara B.
Debeljak-Martačić, Jasmina
Kojadinović, Milica
Ćirković, Saša
Ristić-Đurović, Jasna L.
Trbovich, Alexander M.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
We observed different outcomes upon the subacute exposure to the 128 mT highly homogeneous static magnetic field (SMF) when its orientation was (i) aligned with the vertical component of the geomagnetic field; (ii) in the opposite direction. We employed the fatty acids (FA) composition and digital image analyses (DIA) to provide insights into the underlying processes and examine the possible weak SMF effects. Swiss-Webster male mice were whole-body exposed for 1 h/day over five days. Brain tissue’s thin liquid chromatography resulted in brain FA composition, indicating a possible sequence of changes due to the SMF exposure. Quantitative DIA accurately assessed different image parameters. Delicate textural changes were revealed in the group where pathohistological or biochemical alterations have not been detected. DIA-based biological markers seem to be very promising for studying delicate tissue changes, which results from the high sensitivity and wide availability of DIA.
Кључне речи:
Brain fatty acids (FA) / Fractal (dimension/lacunarity) and multifractal analysis / Gray level co-occurrence matrix (GLCM) statistical features / Histograms of the local fractal dimension distributions / Thin liquid chromatography (TLC) and gas liquid chromatography (GC) / Vertical homogeneous static magnetic field (SMF) of different orientationsИзвор:
Environmental Toxicology and Pharmacology, 2022, 92, 103853-Издавач:
- Elsevier
Финансирање / пројекти:
- Функционална геномика хипоталамуса и медуле у хипертензији индукованој хроничним стресом (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41013)
- Контрола инфекција апикомплексним патогенима: од нових места деловања лека до предикције (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41019)
- Биолошки механизми, нутритивни унос и статус полинезасићених масних киселина и фолата: Унапређење исхране у Србији (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41030)
- Оптоелектронски нанодимензиони системи - пут ка примени (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45003)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200015 (Универзитет у Београду, Институт за медицинска истраживања) (RS-MESTD-inst-2020-200015)
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Ilić, Andjelija Ž. AU - De Luka, Silvio R. AU - Popović, Tamara B. AU - Debeljak-Martačić, Jasmina AU - Kojadinović, Milica AU - Ćirković, Saša AU - Ristić-Đurović, Jasna L. AU - Trbovich, Alexander M. PY - 2022 UR - http://rimi.imi.bg.ac.rs/handle/123456789/1229 AB - We observed different outcomes upon the subacute exposure to the 128 mT highly homogeneous static magnetic field (SMF) when its orientation was (i) aligned with the vertical component of the geomagnetic field; (ii) in the opposite direction. We employed the fatty acids (FA) composition and digital image analyses (DIA) to provide insights into the underlying processes and examine the possible weak SMF effects. Swiss-Webster male mice were whole-body exposed for 1 h/day over five days. Brain tissue’s thin liquid chromatography resulted in brain FA composition, indicating a possible sequence of changes due to the SMF exposure. Quantitative DIA accurately assessed different image parameters. Delicate textural changes were revealed in the group where pathohistological or biochemical alterations have not been detected. DIA-based biological markers seem to be very promising for studying delicate tissue changes, which results from the high sensitivity and wide availability of DIA. PB - Elsevier T2 - Environmental Toxicology and Pharmacology T1 - Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure SP - 103853 VL - 92 DO - 10.1016/j.etap.2022.103853 ER -
@article{ author = "Ilić, Andjelija Ž. and De Luka, Silvio R. and Popović, Tamara B. and Debeljak-Martačić, Jasmina and Kojadinović, Milica and Ćirković, Saša and Ristić-Đurović, Jasna L. and Trbovich, Alexander M.", year = "2022", abstract = "We observed different outcomes upon the subacute exposure to the 128 mT highly homogeneous static magnetic field (SMF) when its orientation was (i) aligned with the vertical component of the geomagnetic field; (ii) in the opposite direction. We employed the fatty acids (FA) composition and digital image analyses (DIA) to provide insights into the underlying processes and examine the possible weak SMF effects. Swiss-Webster male mice were whole-body exposed for 1 h/day over five days. Brain tissue’s thin liquid chromatography resulted in brain FA composition, indicating a possible sequence of changes due to the SMF exposure. Quantitative DIA accurately assessed different image parameters. Delicate textural changes were revealed in the group where pathohistological or biochemical alterations have not been detected. DIA-based biological markers seem to be very promising for studying delicate tissue changes, which results from the high sensitivity and wide availability of DIA.", publisher = "Elsevier", journal = "Environmental Toxicology and Pharmacology", title = "Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure", pages = "103853", volume = "92", doi = "10.1016/j.etap.2022.103853" }
Ilić, A. Ž., De Luka, S. R., Popović, T. B., Debeljak-Martačić, J., Kojadinović, M., Ćirković, S., Ristić-Đurović, J. L.,& Trbovich, A. M.. (2022). Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure. in Environmental Toxicology and Pharmacology Elsevier., 92, 103853. https://doi.org/10.1016/j.etap.2022.103853
Ilić AŽ, De Luka SR, Popović TB, Debeljak-Martačić J, Kojadinović M, Ćirković S, Ristić-Đurović JL, Trbovich AM. Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure. in Environmental Toxicology and Pharmacology. 2022;92:103853. doi:10.1016/j.etap.2022.103853 .
Ilić, Andjelija Ž., De Luka, Silvio R., Popović, Tamara B., Debeljak-Martačić, Jasmina, Kojadinović, Milica, Ćirković, Saša, Ristić-Đurović, Jasna L., Trbovich, Alexander M., "Distinct fatty acid redistribution and textural changes in the brain tissue upon the static magnetic field exposure" in Environmental Toxicology and Pharmacology, 92 (2022):103853, https://doi.org/10.1016/j.etap.2022.103853 . .