Potential infectivity of anaplasma phagocytophilum strains in ixodes ricinus ticks from Serbia
Само за регистроване кориснике
2010
Аутори
Tomanović, SnežanaRadulović, Željko
Masuzawa, Toshiyuki
Milutinović, Marija
Stanisavljević, Ljubiša
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Anaplasma phagocytophilum strains from different geographical regions are characterised by diverse potential infectivity for humans and domesticated animals. We investigated the potential pathogenicity of A. phagocytophilum strains in Ixodes ricinus ticks from 11 geographically different localities in Serbia. Sequences obtained in this study showed a high variability of p44 paralogues. Some of them, however, formed groups with similarities greater than 86% ('similarity groups'). Previous studies showed that 'similarity groups' were nearly always country specific. Our results correlated with this observation, and we also observed significant clustering of paralogues according to vector and reservoir origin of A. phagocytophilum strains. According to the high genetic similarity of sequences isolated from ticks collected in four localities, namely Avala, Batrovci, Hajducka cesma and Ljubovija, with paralogues with proven pathogenicity isolated from human granulocytic anaplasmosis (HGA) pa...tients and A. phagocytophilum infected sheep, we could assume that strains with potential infectivity for humans and domestic animals were present in Serbia.
Кључне речи:
Anaplasma phagocytophilum / pathogenicity / Ixodes ricinus / ticks / sheep / humanИзвор:
Acta Veterinaria Hungarica, 2010, 58, 2, 231-242Издавач:
- Akademiai Kiado Zrt, Budapest
Финансирање / пројекти:
- Chiba Institute of Science (CIS)
- Инфекције интерцелуларним микроорганизмима растућег значаја: трансмисија, однос патоген-домаћин, молекуларна епидемиологија и клинички значај (RS-MESTD-MPN2006-2010-145002)
DOI: 10.1556/AVet.58.2010.2.9
ISSN: 0236-6290
PubMed: 20460222
WoS: 000277593600009
Scopus: 2-s2.0-77952508813
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Tomanović, Snežana AU - Radulović, Željko AU - Masuzawa, Toshiyuki AU - Milutinović, Marija AU - Stanisavljević, Ljubiša PY - 2010 UR - http://rimi.imi.bg.ac.rs/handle/123456789/293 AB - Anaplasma phagocytophilum strains from different geographical regions are characterised by diverse potential infectivity for humans and domesticated animals. We investigated the potential pathogenicity of A. phagocytophilum strains in Ixodes ricinus ticks from 11 geographically different localities in Serbia. Sequences obtained in this study showed a high variability of p44 paralogues. Some of them, however, formed groups with similarities greater than 86% ('similarity groups'). Previous studies showed that 'similarity groups' were nearly always country specific. Our results correlated with this observation, and we also observed significant clustering of paralogues according to vector and reservoir origin of A. phagocytophilum strains. According to the high genetic similarity of sequences isolated from ticks collected in four localities, namely Avala, Batrovci, Hajducka cesma and Ljubovija, with paralogues with proven pathogenicity isolated from human granulocytic anaplasmosis (HGA) patients and A. phagocytophilum infected sheep, we could assume that strains with potential infectivity for humans and domestic animals were present in Serbia. PB - Akademiai Kiado Zrt, Budapest T2 - Acta Veterinaria Hungarica T1 - Potential infectivity of anaplasma phagocytophilum strains in ixodes ricinus ticks from Serbia EP - 242 IS - 2 SP - 231 VL - 58 DO - 10.1556/AVet.58.2010.2.9 ER -
@article{ author = "Tomanović, Snežana and Radulović, Željko and Masuzawa, Toshiyuki and Milutinović, Marija and Stanisavljević, Ljubiša", year = "2010", abstract = "Anaplasma phagocytophilum strains from different geographical regions are characterised by diverse potential infectivity for humans and domesticated animals. We investigated the potential pathogenicity of A. phagocytophilum strains in Ixodes ricinus ticks from 11 geographically different localities in Serbia. Sequences obtained in this study showed a high variability of p44 paralogues. Some of them, however, formed groups with similarities greater than 86% ('similarity groups'). Previous studies showed that 'similarity groups' were nearly always country specific. Our results correlated with this observation, and we also observed significant clustering of paralogues according to vector and reservoir origin of A. phagocytophilum strains. According to the high genetic similarity of sequences isolated from ticks collected in four localities, namely Avala, Batrovci, Hajducka cesma and Ljubovija, with paralogues with proven pathogenicity isolated from human granulocytic anaplasmosis (HGA) patients and A. phagocytophilum infected sheep, we could assume that strains with potential infectivity for humans and domestic animals were present in Serbia.", publisher = "Akademiai Kiado Zrt, Budapest", journal = "Acta Veterinaria Hungarica", title = "Potential infectivity of anaplasma phagocytophilum strains in ixodes ricinus ticks from Serbia", pages = "242-231", number = "2", volume = "58", doi = "10.1556/AVet.58.2010.2.9" }
Tomanović, S., Radulović, Ž., Masuzawa, T., Milutinović, M.,& Stanisavljević, L.. (2010). Potential infectivity of anaplasma phagocytophilum strains in ixodes ricinus ticks from Serbia. in Acta Veterinaria Hungarica Akademiai Kiado Zrt, Budapest., 58(2), 231-242. https://doi.org/10.1556/AVet.58.2010.2.9
Tomanović S, Radulović Ž, Masuzawa T, Milutinović M, Stanisavljević L. Potential infectivity of anaplasma phagocytophilum strains in ixodes ricinus ticks from Serbia. in Acta Veterinaria Hungarica. 2010;58(2):231-242. doi:10.1556/AVet.58.2010.2.9 .
Tomanović, Snežana, Radulović, Željko, Masuzawa, Toshiyuki, Milutinović, Marija, Stanisavljević, Ljubiša, "Potential infectivity of anaplasma phagocytophilum strains in ixodes ricinus ticks from Serbia" in Acta Veterinaria Hungarica, 58, no. 2 (2010):231-242, https://doi.org/10.1556/AVet.58.2010.2.9 . .