Chorioamnionitis and Ontogeny of Circulating Prostaglandin and Thromboxane in Preterm Infants
Само за регистроване кориснике
2008
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Our objective was to determine the effect of chorioamnionitis on plasma prostaglandin E2 (PGE2) and thromboxane 132 (TxB2) during the first week in preterm infants. Plasma PGE2 and TxB2 were measured at 1, 3, and 7 days of age in preterm infants (birth weights 501 to 1500 g), with (n = 26) and without (n = 22) chorioamnionitis. Infants with maternal chorioamnionitis had significantly lower mean gestational age (p = 0.0001) and birth weight (p = 0.03) and a marginally higher rate of bronchopulmonary dysplasia (37% versus 12.5, p = 0.05), a result that may be related to the lower mean gestational age. Plasma PGE2 and TxB2 varied widely, more so on the first day but did not significantly differ between the two groups. TxB2 was lower among infants who died or developed morbidities. Circulating PGE2 and TxB2 concentrations in preterm infants in the first week vary considerably, are relatively unaltered by chorioamnionitis, and are lower in association with mortality and clinical morbidities.... Further research on their role in the causation of adverse neonatal outcomes is necessary.
Кључне речи:
Prostaglandin / thromboxane / preterm / chorioamnionitisИзвор:
American Journal of Perinatology, 2008, 25, 8, 491-497Издавач:
- Thieme Medical Publ Inc, New York
Финансирање / пројекти:
- Sarnaik Endowment for Resident and Fellow Research
- Children's Research Center of Michigan, Detroit, MI
DOI: 10.1055/s-0028-1085068
ISSN: 0735-1631
PubMed: 18726836
WoS: 000260222000004
Scopus: 2-s2.0-55449101021
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Natarajan, Girija AU - Glibetić, Marija AU - Thomas, Ronald L. AU - Aranda, Jacob V. PY - 2008 UR - http://rimi.imi.bg.ac.rs/handle/123456789/206 AB - Our objective was to determine the effect of chorioamnionitis on plasma prostaglandin E2 (PGE2) and thromboxane 132 (TxB2) during the first week in preterm infants. Plasma PGE2 and TxB2 were measured at 1, 3, and 7 days of age in preterm infants (birth weights 501 to 1500 g), with (n = 26) and without (n = 22) chorioamnionitis. Infants with maternal chorioamnionitis had significantly lower mean gestational age (p = 0.0001) and birth weight (p = 0.03) and a marginally higher rate of bronchopulmonary dysplasia (37% versus 12.5, p = 0.05), a result that may be related to the lower mean gestational age. Plasma PGE2 and TxB2 varied widely, more so on the first day but did not significantly differ between the two groups. TxB2 was lower among infants who died or developed morbidities. Circulating PGE2 and TxB2 concentrations in preterm infants in the first week vary considerably, are relatively unaltered by chorioamnionitis, and are lower in association with mortality and clinical morbidities. Further research on their role in the causation of adverse neonatal outcomes is necessary. PB - Thieme Medical Publ Inc, New York T2 - American Journal of Perinatology T1 - Chorioamnionitis and Ontogeny of Circulating Prostaglandin and Thromboxane in Preterm Infants EP - 497 IS - 8 SP - 491 VL - 25 DO - 10.1055/s-0028-1085068 ER -
@article{ author = "Natarajan, Girija and Glibetić, Marija and Thomas, Ronald L. and Aranda, Jacob V.", year = "2008", abstract = "Our objective was to determine the effect of chorioamnionitis on plasma prostaglandin E2 (PGE2) and thromboxane 132 (TxB2) during the first week in preterm infants. Plasma PGE2 and TxB2 were measured at 1, 3, and 7 days of age in preterm infants (birth weights 501 to 1500 g), with (n = 26) and without (n = 22) chorioamnionitis. Infants with maternal chorioamnionitis had significantly lower mean gestational age (p = 0.0001) and birth weight (p = 0.03) and a marginally higher rate of bronchopulmonary dysplasia (37% versus 12.5, p = 0.05), a result that may be related to the lower mean gestational age. Plasma PGE2 and TxB2 varied widely, more so on the first day but did not significantly differ between the two groups. TxB2 was lower among infants who died or developed morbidities. Circulating PGE2 and TxB2 concentrations in preterm infants in the first week vary considerably, are relatively unaltered by chorioamnionitis, and are lower in association with mortality and clinical morbidities. Further research on their role in the causation of adverse neonatal outcomes is necessary.", publisher = "Thieme Medical Publ Inc, New York", journal = "American Journal of Perinatology", title = "Chorioamnionitis and Ontogeny of Circulating Prostaglandin and Thromboxane in Preterm Infants", pages = "497-491", number = "8", volume = "25", doi = "10.1055/s-0028-1085068" }
Natarajan, G., Glibetić, M., Thomas, R. L.,& Aranda, J. V.. (2008). Chorioamnionitis and Ontogeny of Circulating Prostaglandin and Thromboxane in Preterm Infants. in American Journal of Perinatology Thieme Medical Publ Inc, New York., 25(8), 491-497. https://doi.org/10.1055/s-0028-1085068
Natarajan G, Glibetić M, Thomas RL, Aranda JV. Chorioamnionitis and Ontogeny of Circulating Prostaglandin and Thromboxane in Preterm Infants. in American Journal of Perinatology. 2008;25(8):491-497. doi:10.1055/s-0028-1085068 .
Natarajan, Girija, Glibetić, Marija, Thomas, Ronald L., Aranda, Jacob V., "Chorioamnionitis and Ontogeny of Circulating Prostaglandin and Thromboxane in Preterm Infants" in American Journal of Perinatology, 25, no. 8 (2008):491-497, https://doi.org/10.1055/s-0028-1085068 . .