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Transforming growth factor-β superfamily, implications in development and differentiation of stem cells
(De Gruyter, 2012)
Transforming growth factor-β (TGF-β) family members, including TGF-βs and bone morphogenetic proteins (BMPs), play important roles in directing the fate of stem cells. In embryonic stem cells, the TGF-β superfamily ...
SKIP Downregulation Increases TGF-β1-Induced Matrix Metalloproteinase-9 Production in Transformed Keratinocytes
(Scientifica, 2012)
Transforming growth factor-beta (TGF-β1) is a potent inductor of matrix metalloproteinase-9 (MMP-9) in transformed cells. Recently, Ski-interacting protein (SKIP) has been described as a regulator of TGF-β1 signal transduction, ...
TGF-β and MMPs: A complex regulatory loop involved in tumor progression
(Matrix Metalloproteinases: Biology, Functions & Clinical Implications, 2012)
Transforming growth factor-β (TGF-β) has a dual and contradictory role in cancer. It is a tumor suppressor at early stages of tumor formation by virtue of its growth inhibitory and pro-apoptotic functions. However, at later ...
JAK-STAT and AKT pathway-coupled genes in erythroid progenitor cells through ontogeny
(BMC, London, 2012)
Background: It has been reported that the phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway regulates erythropoietin (EPO)-induced survival, proliferation, and maturation of early erythroid progenitors. Erythroid ...
Alternating Consecutive Maximum Contraction as a Test of Muscle Function in Athletes Following ACL Reconstruction
(De Gruyter Poland Sp Zoo, Warsaw, 2012)
The novel test based on isometric alternating consecutive maximal contractions performed by two antagonistic muscles has been recently proposed as a test of muscle function in healthy subjects. The aim of this study was ...
The effects of omega 3 fatty acid supplementation on brain tissue oxidative status in aged wistar rats
(Lithographia, Thessaloniki, 2012)
Background: The omega 3 fatty acids play an important role in many physiological processes. Their effect is well documented in neurodegenerative diseases and inflammatory diseases. Also, aging as a biophysiological process ...
Encapsulation of natural antioxidant resveratrol in liposomes
(CEFood 2012 - Proceedings of 6th Central European Congress on Food, 2012)
Liposomes have been shown to be suitable systems for encapsulation and preserving the health-beneficial properties of a wide range of biological active ingredients such as resveratrol (RSV). The aim of this study was to ...
Lower Serum Paraoxonase-1 Activity Is Related to Linoleic and Docosahexanoic Fatty Acids in Type 2 Diabetic Patients
(Elsevier Science Inc, New York, 2012)
Background. Serum paraoxonase-1(PON-1) activity is decreased in clinical conditions associated with low high-density lipoprotein cholesterol (HDL-C), increased lipid peroxidation and low-grade chronic inflammation, as in ...
Comprehension of exhaustive wh-questions of typically developing preschool children
(Institut za pedagoška istraživanja, Beograd, 2012)
Wh-questions are among the most important and the most frequent types of utterance, which presumably reflects the role of questions in everyday life in gathering various types of information. There is a limited body of ...
Significance of pathohistological findings and the expression of Bcl-2 in diagnosis and treatment of oral planocellular carcinoma / Značaj patohistološkog nalaza i ekspresije Bcl-2 za prognozu i lečenje oralnog planocelularnog karcinoma
(Vojnomedicinska akademija - Institut za naučne informacije, Beograd, 2012)
Background/Aim. Numerous studies were aimed to detect and characterize various tumor markers in patients with oral planocellular carcinoma in order to reduce moratlity and mobidity rates of these patients, as well as to ...