FooDrugs: a comprehensive food–drug interactions database with text documents and transcriptional data
Аутори
Lacruz-Pleguezuelos, BlancaPiette, Oscar
Garranzo, Marco
Pérez-Serrano, David
Milešević, Jelena
Espinosa-Salinas, Isabel
Ramírez de Molina, Ana
Laguna, Teresa
Carrillo de Santa Pau, Enrique
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Food–drug interactions (FDIs) occur when a food item alters the pharmacokinetics or pharmacodynamics of a drug. FDIs can be clinically relevant, as they can hamper or enhance the therapeutic effects of a drug and impact both their efficacy and their safety. However, knowledge of FDIs in clinical practice is limited. This is partially due to the lack of resources focused on FDIs. Here, we describe FooDrugs, a database that centralizes FDI knowledge retrieved from two different approaches: a natural processing language pipeline that extracts potential FDIs from scientific documents and clinical trials and a molecular similarity approach based on the comparison of gene expression alterations caused by foods and drugs. FooDrugs database stores a total of 3 430 062 potential FDIs, with 1 108 429 retrieved from scientific documents and 2 321 633 inferred from molecular data. This resource aims to provide researchers and clinicians with a centralized repository for potential FDI information t...hat is free and easy to use.
Извор:
Database, 2023, 2023, baad075-Издавач:
- Oxford University Press
Финансирање / пројекти:
- European Union’s Horizon 2020 Research and Innovation programme (H2020-EU.3.2.2.3.—A sustainable and competitive agri-food industry) (Grant Agreement No. 863059)
- Institute of Health Carlos III (project IMPaCT-Data, exp. IMP/00019)
- the European Union, European Regional Development Fund (‘A way to make Europe’); AI4FOOD-CM (Y2020/TCS-6654) project
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Lacruz-Pleguezuelos, Blanca AU - Piette, Oscar AU - Garranzo, Marco AU - Pérez-Serrano, David AU - Milešević, Jelena AU - Espinosa-Salinas, Isabel AU - Ramírez de Molina, Ana AU - Laguna, Teresa AU - Carrillo de Santa Pau, Enrique PY - 2023 UR - http://rimi.imi.bg.ac.rs/handle/123456789/1401 AB - Food–drug interactions (FDIs) occur when a food item alters the pharmacokinetics or pharmacodynamics of a drug. FDIs can be clinically relevant, as they can hamper or enhance the therapeutic effects of a drug and impact both their efficacy and their safety. However, knowledge of FDIs in clinical practice is limited. This is partially due to the lack of resources focused on FDIs. Here, we describe FooDrugs, a database that centralizes FDI knowledge retrieved from two different approaches: a natural processing language pipeline that extracts potential FDIs from scientific documents and clinical trials and a molecular similarity approach based on the comparison of gene expression alterations caused by foods and drugs. FooDrugs database stores a total of 3 430 062 potential FDIs, with 1 108 429 retrieved from scientific documents and 2 321 633 inferred from molecular data. This resource aims to provide researchers and clinicians with a centralized repository for potential FDI information that is free and easy to use. PB - Oxford University Press T2 - Database T1 - FooDrugs: a comprehensive food–drug interactions database with text documents and transcriptional data SP - baad075 VL - 2023 DO - 10.1093/database/baad075 ER -
@article{ author = "Lacruz-Pleguezuelos, Blanca and Piette, Oscar and Garranzo, Marco and Pérez-Serrano, David and Milešević, Jelena and Espinosa-Salinas, Isabel and Ramírez de Molina, Ana and Laguna, Teresa and Carrillo de Santa Pau, Enrique", year = "2023", abstract = "Food–drug interactions (FDIs) occur when a food item alters the pharmacokinetics or pharmacodynamics of a drug. FDIs can be clinically relevant, as they can hamper or enhance the therapeutic effects of a drug and impact both their efficacy and their safety. However, knowledge of FDIs in clinical practice is limited. This is partially due to the lack of resources focused on FDIs. Here, we describe FooDrugs, a database that centralizes FDI knowledge retrieved from two different approaches: a natural processing language pipeline that extracts potential FDIs from scientific documents and clinical trials and a molecular similarity approach based on the comparison of gene expression alterations caused by foods and drugs. FooDrugs database stores a total of 3 430 062 potential FDIs, with 1 108 429 retrieved from scientific documents and 2 321 633 inferred from molecular data. This resource aims to provide researchers and clinicians with a centralized repository for potential FDI information that is free and easy to use.", publisher = "Oxford University Press", journal = "Database", title = "FooDrugs: a comprehensive food–drug interactions database with text documents and transcriptional data", pages = "baad075", volume = "2023", doi = "10.1093/database/baad075" }
Lacruz-Pleguezuelos, B., Piette, O., Garranzo, M., Pérez-Serrano, D., Milešević, J., Espinosa-Salinas, I., Ramírez de Molina, A., Laguna, T.,& Carrillo de Santa Pau, E.. (2023). FooDrugs: a comprehensive food–drug interactions database with text documents and transcriptional data. in Database Oxford University Press., 2023, baad075. https://doi.org/10.1093/database/baad075
Lacruz-Pleguezuelos B, Piette O, Garranzo M, Pérez-Serrano D, Milešević J, Espinosa-Salinas I, Ramírez de Molina A, Laguna T, Carrillo de Santa Pau E. FooDrugs: a comprehensive food–drug interactions database with text documents and transcriptional data. in Database. 2023;2023:baad075. doi:10.1093/database/baad075 .
Lacruz-Pleguezuelos, Blanca, Piette, Oscar, Garranzo, Marco, Pérez-Serrano, David, Milešević, Jelena, Espinosa-Salinas, Isabel, Ramírez de Molina, Ana, Laguna, Teresa, Carrillo de Santa Pau, Enrique, "FooDrugs: a comprehensive food–drug interactions database with text documents and transcriptional data" in Database, 2023 (2023):baad075, https://doi.org/10.1093/database/baad075 . .