Polyunsaturated fatty acids phospholipids profiles in plasma and liver in Wistar rats of different age
Аутори
Popović, TamaraDebeljak-Martačić, Jasmina
Arsić, Aleksandra
Ranković, Slavica
Pokimica, Biljana
Glibetić, Marija
Конференцијски прилог (Објављена верзија)
,
FEBS Balaton
Метаподаци
Приказ свих података о документуАпстракт
The phospholipids class, fatty acids (FAs) composition and cholesterol content in membranes are basic determinants of the physical properties of membranes. They been shown to influence a wide variety of membrane dependent functions such as membrane transport, enzyme activity and receptor function. The FAs profile in tissues partly reflects not only the dietary fat intake, but also the efficiency of FAs metabolism in the body.
We examined overall saturated (SFA), monounsaturated (MUFA) polyunsaturated (PUFA) fatty acids phospholipids profiles in plasma and liver in male Wistar rats of different age (n=10; 3 months and n=10; 22 mouths), as well as overall n-3, n-6 and n-6/n-3 ratio. We determined it by GC cromatography.
Results showed deferent tissue specificity and age specificity also. In young rats plasma phospholipids MUFA were increased (p<0.01), while PUFA and n-6 were decreased (p<0.01)compared to aged rats.In liver phospholipids in young rats overall n-3 were increased (p<0.001...), while overall N-6/n-3 ratio was ssignificantly decreased (p<0.001) compared to aged rats.
Liver as a place of biosynthesis and degradation of FAs seems to have more pronounced changes in its phospholipids profiles in aging.
Извор:
FEBS3+ Meeting "From molecules to living systems", 2018 September 2 – 5, Siofok, Hungary - Final Programme & Book of Abstracts, 2018, P2-02-Издавач:
- FEBS Balaton 2018
Институција/група
Institut za medicinska istraživanjaTY - CONF AU - Popović, Tamara AU - Debeljak-Martačić, Jasmina AU - Arsić, Aleksandra AU - Ranković, Slavica AU - Pokimica, Biljana AU - Glibetić, Marija PY - 2018 UR - http://rimi.imi.bg.ac.rs/handle/123456789/1383 AB - The phospholipids class, fatty acids (FAs) composition and cholesterol content in membranes are basic determinants of the physical properties of membranes. They been shown to influence a wide variety of membrane dependent functions such as membrane transport, enzyme activity and receptor function. The FAs profile in tissues partly reflects not only the dietary fat intake, but also the efficiency of FAs metabolism in the body. We examined overall saturated (SFA), monounsaturated (MUFA) polyunsaturated (PUFA) fatty acids phospholipids profiles in plasma and liver in male Wistar rats of different age (n=10; 3 months and n=10; 22 mouths), as well as overall n-3, n-6 and n-6/n-3 ratio. We determined it by GC cromatography. Results showed deferent tissue specificity and age specificity also. In young rats plasma phospholipids MUFA were increased (p<0.01), while PUFA and n-6 were decreased (p<0.01)compared to aged rats.In liver phospholipids in young rats overall n-3 were increased (p<0.001), while overall N-6/n-3 ratio was ssignificantly decreased (p<0.001) compared to aged rats. Liver as a place of biosynthesis and degradation of FAs seems to have more pronounced changes in its phospholipids profiles in aging. PB - FEBS Balaton 2018 C3 - FEBS3+ Meeting "From molecules to living systems", 2018 September 2 – 5, Siofok, Hungary - Final Programme & Book of Abstracts T1 - Polyunsaturated fatty acids phospholipids profiles in plasma and liver in Wistar rats of different age SP - P2-02 UR - https://hdl.handle.net/21.15107/rcub_rimi_1383 ER -
@conference{ author = "Popović, Tamara and Debeljak-Martačić, Jasmina and Arsić, Aleksandra and Ranković, Slavica and Pokimica, Biljana and Glibetić, Marija", year = "2018", abstract = "The phospholipids class, fatty acids (FAs) composition and cholesterol content in membranes are basic determinants of the physical properties of membranes. They been shown to influence a wide variety of membrane dependent functions such as membrane transport, enzyme activity and receptor function. The FAs profile in tissues partly reflects not only the dietary fat intake, but also the efficiency of FAs metabolism in the body. We examined overall saturated (SFA), monounsaturated (MUFA) polyunsaturated (PUFA) fatty acids phospholipids profiles in plasma and liver in male Wistar rats of different age (n=10; 3 months and n=10; 22 mouths), as well as overall n-3, n-6 and n-6/n-3 ratio. We determined it by GC cromatography. Results showed deferent tissue specificity and age specificity also. In young rats plasma phospholipids MUFA were increased (p<0.01), while PUFA and n-6 were decreased (p<0.01)compared to aged rats.In liver phospholipids in young rats overall n-3 were increased (p<0.001), while overall N-6/n-3 ratio was ssignificantly decreased (p<0.001) compared to aged rats. Liver as a place of biosynthesis and degradation of FAs seems to have more pronounced changes in its phospholipids profiles in aging.", publisher = "FEBS Balaton 2018", journal = "FEBS3+ Meeting "From molecules to living systems", 2018 September 2 – 5, Siofok, Hungary - Final Programme & Book of Abstracts", title = "Polyunsaturated fatty acids phospholipids profiles in plasma and liver in Wistar rats of different age", pages = "P2-02", url = "https://hdl.handle.net/21.15107/rcub_rimi_1383" }
Popović, T., Debeljak-Martačić, J., Arsić, A., Ranković, S., Pokimica, B.,& Glibetić, M.. (2018). Polyunsaturated fatty acids phospholipids profiles in plasma and liver in Wistar rats of different age. in FEBS3+ Meeting "From molecules to living systems", 2018 September 2 – 5, Siofok, Hungary - Final Programme & Book of Abstracts FEBS Balaton 2018., P2-02. https://hdl.handle.net/21.15107/rcub_rimi_1383
Popović T, Debeljak-Martačić J, Arsić A, Ranković S, Pokimica B, Glibetić M. Polyunsaturated fatty acids phospholipids profiles in plasma and liver in Wistar rats of different age. in FEBS3+ Meeting "From molecules to living systems", 2018 September 2 – 5, Siofok, Hungary - Final Programme & Book of Abstracts. 2018;:P2-02. https://hdl.handle.net/21.15107/rcub_rimi_1383 .
Popović, Tamara, Debeljak-Martačić, Jasmina, Arsić, Aleksandra, Ranković, Slavica, Pokimica, Biljana, Glibetić, Marija, "Polyunsaturated fatty acids phospholipids profiles in plasma and liver in Wistar rats of different age" in FEBS3+ Meeting "From molecules to living systems", 2018 September 2 – 5, Siofok, Hungary - Final Programme & Book of Abstracts (2018):P2-02, https://hdl.handle.net/21.15107/rcub_rimi_1383 .