Relationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Relationships between the structural characteristic of curcumin and dimethoxycurcumin and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with the curcumin and dimethoxycurcumin resulted in apoptosis induction and dose-dependent inhibition of cell proliferation. The calculated docking and the DFT method, suggest a structure-activity relationship between the activities of dimethoxycurcumin and curcumin structure and the apoptosis in HepG2 cells
Кључне речи:
curcumins / hepatocarcinomaИзвор:
Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry, 2023, 80, 599, 175-179Издавач:
- Asociacion de Quimicos del Instituto Quimico de Sarria
Институција/група
Institut za medicinska istraživanjaTY - JOUR AU - Ramirez-Tagle, Rodrigo AU - Alvarado-Soto, Leonor AU - Santibanez, Juan F. AU - Echeverria, Cesar PY - 2023 UR - http://rimi.imi.bg.ac.rs/handle/123456789/1361 AB - Relationships between the structural characteristic of curcumin and dimethoxycurcumin and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with the curcumin and dimethoxycurcumin resulted in apoptosis induction and dose-dependent inhibition of cell proliferation. The calculated docking and the DFT method, suggest a structure-activity relationship between the activities of dimethoxycurcumin and curcumin structure and the apoptosis in HepG2 cells PB - Asociacion de Quimicos del Instituto Quimico de Sarria T2 - Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry T2 - Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry T1 - Relationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells EP - 179 IS - 599 SP - 175 VL - 80 DO - 10.55815/417980 ER -
@article{ author = "Ramirez-Tagle, Rodrigo and Alvarado-Soto, Leonor and Santibanez, Juan F. and Echeverria, Cesar", year = "2023", abstract = "Relationships between the structural characteristic of curcumin and dimethoxycurcumin and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with the curcumin and dimethoxycurcumin resulted in apoptosis induction and dose-dependent inhibition of cell proliferation. The calculated docking and the DFT method, suggest a structure-activity relationship between the activities of dimethoxycurcumin and curcumin structure and the apoptosis in HepG2 cells", publisher = "Asociacion de Quimicos del Instituto Quimico de Sarria", journal = "Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry, Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry", title = "Relationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells", pages = "179-175", number = "599", volume = "80", doi = "10.55815/417980" }
Ramirez-Tagle, R., Alvarado-Soto, L., Santibanez, J. F.,& Echeverria, C.. (2023). Relationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells. in Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry Asociacion de Quimicos del Instituto Quimico de Sarria., 80(599), 175-179. https://doi.org/10.55815/417980
Ramirez-Tagle R, Alvarado-Soto L, Santibanez JF, Echeverria C. Relationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells. in Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry. 2023;80(599):175-179. doi:10.55815/417980 .
Ramirez-Tagle, Rodrigo, Alvarado-Soto, Leonor, Santibanez, Juan F., Echeverria, Cesar, "Relationships between the structural characteristic of curcumins that affect cell proliferation of hepatocarcinoma cells" in Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry, 80, no. 599 (2023):175-179, https://doi.org/10.55815/417980 . .