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Prikaz rezultata 11-18 od 18
Effects of IL-17 on functional activity of peripheral blood cells / Efekti IL-17 na funkcionalnu aktivnost ćelija periferne krvi
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2004)
Interleukin-17 (IL-17) is a proinflammatory cytokine produced mainly by activated CD4+ and CD8+ T cells, while its specific receptor is ubiquitously distributed. The inflammatory capacity of IL-17 is based on its ability ...
Regulation of S100As Expression by Inflammatory Cytokines in Chronic Lymphocytic Leukemia
(MDPI, 2022)
The calcium-binding proteins S100A4, S100A8, and S100A9 are upregulated in chronic lymphocytic leukemia (CLL), while the S100A9 promotes NF-κB activity during disease progression. The S100-protein family has been involved ...
The role of dietary polyunsaturated fatty acids in inflammation / Uloga polinezasićenih masnih kiselina u inflamaciji
(Univerzitet u Kragujevcu - Fakultet medicinskih nauka, Kragujevac, 2013)
Low-grade systemic inflammation is at the base of the most chronic non-communicable diseases, which are reaching epidemic proportions worldwide. Key players in the regulation of inflammation are n-6 and n-3 polyunsaturated ...
A prospective, randomized, double-blind, placebo-controlled trial of polyphenols on the outcomes of inflammatory factors and oxidative stress in patients with type 2 diabetes mellitus
(Reviews in Cardiovascular MedicineReviews in Cardiovascular Medicine, 2022)
Type 2 diabetes mellitus (T2DM) is commonly associated with hyperglycemia, dyslipidemia, oxidative stress and inflammation which are well known cardiovascular risk factors. Pomegranate peel polyphenols have a proven ...
Aronia (Aronia melanocarpa) Polyphenols Modulate the Microbial Community in a Simulator of the Human Intestinal Microbial Ecosystem (SHIME) and Decrease Secretion of Proinflammatory Markers in a Caco-2/endothelial Cell Coculture Model
(Wiley, Hoboken, 2018)
Scope Results To explore the mechanisms behind the health effects of Aronia (Aronia melanocarpa), the microbial community modulating and anti-inflammatory effects of Aronia polyphenols are investigated by combining the ...
Polyunsaturated fatty acids in health and disease / Polinezasićene masne kiseline u zdravlju i bolesti
(Srpsko hemijsko društvo, Beograd, 2013)
Polyunsaturated fatty acids (PUFAs) are necessary for overall health. Two PUFAs families, n-6 and n-3 fatty acids, are physiologically and metabolically distinct. The proportion of PUFAs in serum and erythrocyte phospholipids, ...
IL-6 stimulation of DNA replication is JAK1/2 mediated in cross-talk with hyperactivated ERK1/2 signaling
(Wiley, Hoboken, 2019)
Myeloproliferative neoplasms (MPNs) are developing resistance to therapy by JAK1/2 inhibitor ruxolitinib. To explore the mechanism of ruxolitinib's limited effect, we examined the JAK1/2 mediated induction of proliferation ...
Novel Patents Targeting Interleukin-17A; Implications in Cancer and Inflammation
(Bentham Science Publ Ltd, Sharjah, 2018)
Background: IL-17A is a founding member of the IL-17 family that has been implicated in the pathogenesis of inflammatory-associated diseases such as cancer and autoimmune disease. In cancer, IL-17A participates in many key ...