TY  - JOUR
AU  - Perović, Svetlana
AU  - Veinović, Gorana
AU  - Antic Stanković, Jelena
PY  - 2018
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/855
AB  - Antimicrobial resistance is a natural biological phenomenon in their struggle for existence and represents a major health care issue, associated with high mortality and morbidity. The first cases of mass emergence of resistant strains were observed in the middle of the 20th century, and since then cases of resistance have been reported all over the world, and in the last two decades even more frequently are reported multiple bacterial resistance. Factors that contribute to the development of bacteria resistance are abuse in the use of antibacterial agents, in humans or livestock, and releases of antibacterial agents into the environment. Moreover, the development of new effective antibiotics is decreasing, contrary to increasing the overall effort for the synthesis of new ones. Identification and reporting of bacterial resistance, as well as monitoring of the use of antibiotics in the outpatient and inpatient setting, today is the obligation of all countries.
PB  - Društvo genetičara Srbije, Beograd
T2  - Genetika-Belgrade
T1  - A review on antibiotic resistance: origin and mechanisms of bacterial resistance as biological phenomenon
EP  - 1135
IS  - 3
SP  - 1123
VL  - 50
DO  - 10.2298/GENSR1803123P
ER  - 

@article{
author = "Perović, Svetlana and Veinović, Gorana and Antic Stanković, Jelena",
year = "2018",
abstract = "Antimicrobial resistance is a natural biological phenomenon in their struggle for existence and represents a major health care issue, associated with high mortality and morbidity. The first cases of mass emergence of resistant strains were observed in the middle of the 20th century, and since then cases of resistance have been reported all over the world, and in the last two decades even more frequently are reported multiple bacterial resistance. Factors that contribute to the development of bacteria resistance are abuse in the use of antibacterial agents, in humans or livestock, and releases of antibacterial agents into the environment. Moreover, the development of new effective antibiotics is decreasing, contrary to increasing the overall effort for the synthesis of new ones. Identification and reporting of bacterial resistance, as well as monitoring of the use of antibiotics in the outpatient and inpatient setting, today is the obligation of all countries.",
publisher = "Društvo genetičara Srbije, Beograd",
journal = "Genetika-Belgrade",
title = "A review on antibiotic resistance: origin and mechanisms of bacterial resistance as biological phenomenon",
pages = "1135-1123",
number = "3",
volume = "50",
doi = "10.2298/GENSR1803123P"
}

Perović, S., Veinović, G.,& Antic Stanković, J.. (2018). A review on antibiotic resistance: origin and mechanisms of bacterial resistance as biological phenomenon. in Genetika-Belgrade
Društvo genetičara Srbije, Beograd., 50(3), 1123-1135.
https://doi.org/10.2298/GENSR1803123P

Perović S, Veinović G, Antic Stanković J. A review on antibiotic resistance: origin and mechanisms of bacterial resistance as biological phenomenon. in Genetika-Belgrade. 2018;50(3):1123-1135.
doi:10.2298/GENSR1803123P .

Perović, Svetlana, Veinović, Gorana, Antic Stanković, Jelena, "A review on antibiotic resistance: origin and mechanisms of bacterial resistance as biological phenomenon" in Genetika-Belgrade, 50, no. 3 (2018):1123-1135,
https://doi.org/10.2298/GENSR1803123P . .

TY  - JOUR
AU  - Besu, Irina
AU  - Srdić-Rajić, Tatjana
AU  - Matić, Ivana Z.
AU  - Janković, Ljiljana
AU  - Besu, Valeri
AU  - Konić-Ristić, Aleksandra
AU  - Juranič, Zorica
PY  - 2017
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/1245
AB  - Despite the numerous benefits of milk constituents for human health a considerable number of the general population follow a milk-restricted diet due to clinically confirmed or self-assessed adverse reactions to cow’s milk consumption. Recurrent aphthous ulcers (RAU) are currently one of the most common oral disorders, with a worldwide distribution and insufficiently defined etiology, which, among other factors, implies the immunological reaction to food proteins. The aim of this study was to determine the immune-reactivity to donkey’s milk proteins in patients with RAU and compare it to the reactivity towards the proteins from cow’s and goat’s milks, in a set of simultaneous experiments. Levels of serum IgA, IgG and IgE antibodies to the same quantity of the examined antigens were determined by enzyme-linked immunosorbent assay. The results indicate that patients with RAU with increased immunity to cow’s milk proteins could consider the use of donkey’s milk as the best protein source.
PB  - Taylor & Francis
T2  - Food and Agricultural Immunology
T1  - The absence of immunoreactivity to donkey’s milk in patients with recurrent aphthous ulcers and immunoreactivity to cow’s milk
EP  - 462
IS  - 3
SP  - 452
VL  - 28
DO  - 10.1080/09540105.2017.1293017
ER  - 

@article{
author = "Besu, Irina and Srdić-Rajić, Tatjana and Matić, Ivana Z. and Janković, Ljiljana and Besu, Valeri and Konić-Ristić, Aleksandra and Juranič, Zorica",
year = "2017",
abstract = "Despite the numerous benefits of milk constituents for human health a considerable number of the general population follow a milk-restricted diet due to clinically confirmed or self-assessed adverse reactions to cow’s milk consumption. Recurrent aphthous ulcers (RAU) are currently one of the most common oral disorders, with a worldwide distribution and insufficiently defined etiology, which, among other factors, implies the immunological reaction to food proteins. The aim of this study was to determine the immune-reactivity to donkey’s milk proteins in patients with RAU and compare it to the reactivity towards the proteins from cow’s and goat’s milks, in a set of simultaneous experiments. Levels of serum IgA, IgG and IgE antibodies to the same quantity of the examined antigens were determined by enzyme-linked immunosorbent assay. The results indicate that patients with RAU with increased immunity to cow’s milk proteins could consider the use of donkey’s milk as the best protein source.",
publisher = "Taylor & Francis",
journal = "Food and Agricultural Immunology",
title = "The absence of immunoreactivity to donkey’s milk in patients with recurrent aphthous ulcers and immunoreactivity to cow’s milk",
pages = "462-452",
number = "3",
volume = "28",
doi = "10.1080/09540105.2017.1293017"
}

Besu, I., Srdić-Rajić, T., Matić, I. Z., Janković, L., Besu, V., Konić-Ristić, A.,& Juranič, Z.. (2017). The absence of immunoreactivity to donkey’s milk in patients with recurrent aphthous ulcers and immunoreactivity to cow’s milk. in Food and Agricultural Immunology
Taylor & Francis., 28(3), 452-462.
https://doi.org/10.1080/09540105.2017.1293017

Besu I, Srdić-Rajić T, Matić IZ, Janković L, Besu V, Konić-Ristić A, Juranič Z. The absence of immunoreactivity to donkey’s milk in patients with recurrent aphthous ulcers and immunoreactivity to cow’s milk. in Food and Agricultural Immunology. 2017;28(3):452-462.
doi:10.1080/09540105.2017.1293017 .

Besu, Irina, Srdić-Rajić, Tatjana, Matić, Ivana Z., Janković, Ljiljana, Besu, Valeri, Konić-Ristić, Aleksandra, Juranič, Zorica, "The absence of immunoreactivity to donkey’s milk in patients with recurrent aphthous ulcers and immunoreactivity to cow’s milk" in Food and Agricultural Immunology, 28, no. 3 (2017):452-462,
https://doi.org/10.1080/09540105.2017.1293017 . .

TY  - JOUR
AU  - Opsenica, Dejan M.
AU  - Radivojević, Jelena
AU  - Matić, Ivana Z.
AU  - Štajner, Tijana
AU  - Knežević-Usaj, Slavica
AU  - Đurković-Đaković, Olgica
AU  - Šolaja, Bogdan
PY  - 2015
UR  - http://rimi.imi.bg.ac.rs/handle/123456789/639
AB  - New cyclohexylidene 1,2,4,5-tetraoxanes with polar guanidine and urea based groups were synthesized and evaluated for their antimalarial activity against chloroquine resistant and susceptible Plasmodium falciparum strains. The derivatives showed moderate, nM range antimalarial activities and low cytotoxicity. The N-phenylurea derivative 24 exhibited the best resistance indices (RIW2 = 0.44, RITM91C235 = 0.80) and was not toxic against human normal peripheral blood mononuclear cells (IC50  gt  200 mu M). Seven derivatives were tested in vitro against four human cancer cell lines and they demonstrated high selectivity toward leukaemia K562 cells. One compound, derivative 21 with a primary amino group, was the first tetraoxane tested in vivo against Toxoplasma gondii as another apicomplexan parasite. Subcutaneous administration at a dose of 10 mg kg(-1) day(-1) for 8 days allowed the survival of 20 % of infected mice, thus demonstrating the high potential of tetraoxanes for the treatment of apicomplexan parasites.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Tetraoxanes as inhibitors of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii growth and anti-cancer molecules
EP  - +
IS  - 11
SP  - 1339
VL  - 80
DO  - 10.2298/JSC150430063O
ER  - 

@article{
author = "Opsenica, Dejan M. and Radivojević, Jelena and Matić, Ivana Z. and Štajner, Tijana and Knežević-Usaj, Slavica and Đurković-Đaković, Olgica and Šolaja, Bogdan",
year = "2015",
abstract = "New cyclohexylidene 1,2,4,5-tetraoxanes with polar guanidine and urea based groups were synthesized and evaluated for their antimalarial activity against chloroquine resistant and susceptible Plasmodium falciparum strains. The derivatives showed moderate, nM range antimalarial activities and low cytotoxicity. The N-phenylurea derivative 24 exhibited the best resistance indices (RIW2 = 0.44, RITM91C235 = 0.80) and was not toxic against human normal peripheral blood mononuclear cells (IC50  gt  200 mu M). Seven derivatives were tested in vitro against four human cancer cell lines and they demonstrated high selectivity toward leukaemia K562 cells. One compound, derivative 21 with a primary amino group, was the first tetraoxane tested in vivo against Toxoplasma gondii as another apicomplexan parasite. Subcutaneous administration at a dose of 10 mg kg(-1) day(-1) for 8 days allowed the survival of 20 % of infected mice, thus demonstrating the high potential of tetraoxanes for the treatment of apicomplexan parasites.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Tetraoxanes as inhibitors of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii growth and anti-cancer molecules",
pages = "+-1339",
number = "11",
volume = "80",
doi = "10.2298/JSC150430063O"
}

Opsenica, D. M., Radivojević, J., Matić, I. Z., Štajner, T., Knežević-Usaj, S., Đurković-Đaković, O.,& Šolaja, B.. (2015). Tetraoxanes as inhibitors of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii growth and anti-cancer molecules. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 80(11), 1339-+.
https://doi.org/10.2298/JSC150430063O

Opsenica DM, Radivojević J, Matić IZ, Štajner T, Knežević-Usaj S, Đurković-Đaković O, Šolaja B. Tetraoxanes as inhibitors of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii growth and anti-cancer molecules. in Journal of the Serbian Chemical Society. 2015;80(11):1339-+.
doi:10.2298/JSC150430063O .

Opsenica, Dejan M., Radivojević, Jelena, Matić, Ivana Z., Štajner, Tijana, Knežević-Usaj, Slavica, Đurković-Đaković, Olgica, Šolaja, Bogdan, "Tetraoxanes as inhibitors of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii growth and anti-cancer molecules" in Journal of the Serbian Chemical Society, 80, no. 11 (2015):1339-+,
https://doi.org/10.2298/JSC150430063O . .